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[1]许衍超,魏武,杨刚,等.清石汤在输尿管软镜碎石术后应用的临床意义[J].医学研究与战创伤救治(原医学研究生学报),2023,25(3):272-275.[doi:10.3969/j.issn.1672-271X.2023.03.010]
　XU Yanchao,WEI Wu,YANG Gang,et al.The clinical significance of Qingshi soup after flexible ureteroscopic lithotripsy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2023,25(3):272-275.[doi:10.3969/j.issn.1672-271X.2023.03.010]
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清石汤在输尿管软镜碎石术后应用的临床意义()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第25卷
期数:
2023年3期
页码:
272-275
栏目:
临床研究
出版日期:
2023-08-01

文章信息/Info

Title:
The clinical significance of Qingshi soup after flexible ureteroscopic lithotripsy
作者:
许衍超; 魏武; 杨刚; 王安喜
作者单位：210022南京，南京市中医院泌尿外科（许衍超、魏武、杨刚、王安喜）
Author(s):
XU Yanchao; WEI Wu; YANG Gang; WANG Anxi
（Department of Urology，Nanjing Hospital of Chinese Medicine，Nanjing 210022，Jiangsu，China)
关键词:
输尿管软镜碎石术; 输尿管支架管; 清石汤; 气滞血瘀型
Keywords:
ureteroscopic lithotripsy;  ureteral stents tube;  Qingshi soup;  Qi stagnation and blood stasis syndrome type
分类号:
R699.4
DOI:
10.3969/j.issn.1672-271X.2023.03.010
文献标志码:
A
摘要:
目的观察清石汤对输尿管软镜碎石术后留置输尿管支架管所导致的肉眼血尿与腰背部不适感等治疗效果，并初步探讨其作用机制。方法回顾性分析南京市中医院泌尿外科2020年6月1日至2021年9月30日收治的肾结石住院患者90例，根据治疗方法不同分为清石汤组和对照组，每组各45例。2 组患者均接受输尿管软镜碎石术，术后均留置输尿管支架管，术后3 d出院，对照组予以坦索罗辛治疗，清石汤组予清石汤治疗。出院后1～4周每周复查尿常规，出院后2周复查腹部平片（KUB），复诊时详细询问肉眼血尿及腰背部不适感等症状。统计2组患者治疗后的病情变化，评价2组患者治疗4周后疗效和安全性。结果清石汤组尿常规白细胞及红细胞计数明显低于对照组，差异有统计学意义（F组间=8.856，P＜0.01；F组间=167.822，P＜0.001）；随着治疗时间的延长，2组的计数均逐渐下降（F时间=429.685，P＜0.001；F时间=453.494，P＜0.001）；2组计数随着治疗时间延长下降幅度不同，清石汤组尿常规白细胞和红细胞计数下降幅度更大（F交互=6.684，P＜0.001；F交互=19.677，P＜0.001）；治疗2周后复查KUB，清石汤组残石率23.0%，对照组残石率35.6%（P＜0.05）。清石汤组在出院后2周，肉眼血尿、腰背部不适感均完全消失，对照组在出院4周后尚有肉眼血尿患者和腰背部不适感患者。结论清石汤对输尿管软镜碎石术后留置输尿管支架管所导致的泌尿系感染、肉眼血尿及腰背部不适感疗效确切，可以有效改善患者临床症状，同时可提高患者的术后残石排出率。
Abstract:
ObjectiveThis study was aimed to observe the effect of Qingshi soup on the gross hematuria and low back discomfort caused by indwelling ureteral stent tube after flexible ureteroscopic lithotripsy，and to preliminarily explore its mechanism.MethodsA retrospective analysis of 90 hospitalized patients with kidney stones admitted to the Department of Urology of Nanjing Hospital of Chinese Medicine from June 1, 2020 to September 30, 2021 was performed. According to the treatment methods, all cases were divided into the experimental group and the control group, 45 cases each group. All patients were underwent flexible ureteroscopic lithotripsy，and all of them were indwelled with ureteral stents after surgery，and were discharged from the hospital 3 days after surgery. The control group was treated with tamsulosin，and the experimental group was treated with Qingshi soup. Routine urine test was reviewed every week for 1 to 4 weeks after discharge，KUB was re-examined 2 weeks after discharge. The symptoms such as gross hematuria，low back discomfort and other symptoms were asked in detail during the follow-up consultation. The changes in the condition of the two groups after treatment were observed，and the efficacy and safety of the two groups after 4 weeks of treatment were evaluated.ResultsThe white blood cell and red blood cell counts of urine in the experimental group were significantly lower than those of the control group (Fgroup=8.856，P<0.01; Fgroup=167.822，P<0.001); with the extension of treatment time，the counts of both groups gradually decreased (Ftime=429.685，P<0.001; Ftime=453.494，P<0.001). The two groups counts decreased differently with extension of treatment time，the white blood cell and red blood cell counts of the experimental group decreased more significantly (Finteraction=6.684，P<0.001; Finteraction=19.677，P<0.001). After 2 weeks of treatment，KUB was found to be 23.0% positive for residual stones of experimental group. The KUB positive rate of residual stones in the control group was 35.6%. In the experimental group，2 weeks later from discharge，the discomfort of gross hematuria and low back completely disappeared. The patients of control group still had discomfort of gross hematuria and low back after 4 weeks after discharge.ConclusionThe effect of Qingshi soup on urinary infection，gross hematuria and low back discomfort caused by indwelling ureteral stent tube after flexible ureteroscopic lithotripsy is exact，which can effectively improve the clinical symptoms of patients and the rate of stone discharge after surgery.

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备注/Memo

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更新日期/Last Update: 2023-08-24