|本期目录/Table of Contents|

[1]成军,孙长贵,戴玉柱,等.驻浙部队HBV感染情况及低浓度HBsAg 流行病学调查[J].医学研究与战创伤救治(原医学研究生学报),2009,11(04):298-301.
　CHENG Jun,SUN Cang-gui,DAI Yu-zhu,et al.HBV infection status and epidemiological investigation of low-level HBsAg in soldiers of PLA stationed in Zhejiang[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2009,11(04):298-301.
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驻浙部队HBV感染情况及低浓度HBsAg 流行病学调查()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第11卷
期数:
2009年04期
页码:
298-301
栏目:
出版日期:
2009-07-20

文章信息/Info

Title:
HBV infection status and epidemiological investigation of low-level HBsAg in soldiers of PLA stationed in Zhejiang
文章编号:
1672-271X(2009)04-0298-04
作者:
成军1; 孙长贵1; 戴玉柱1; 张伟强2; 孙关忠1; 李晓军3
1.解放军第117医院临床实验中心，浙江杭州310013；2.解放军第117医院野战血站，浙江杭州310013；3.南京军区南京总医院，江苏南京210002
Author(s):
CHENG Jun1;  SUN Cang-gui 1;  DAI Yu-zhu1;  ZHANG Wei-qiang 2;  SUN Guan-zhong 1;  LI Xiao-jun 3
1.Clinical Experimental Center, the 117th Hospital of PLA, Hangzhou 310013, Zhejiang, China;2.Field Armies’Blood Station, the 117th Hospital of PLA, Hangzhou 310013, Zhejiang, China;3.General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu, China
关键词:
乙型肝炎病毒标志物; HBV感染; 乙型肝炎表面抗原; 乙型肝炎病毒核酸
Keywords:
Markers of hepatitis B virus;  HBV infection;  HBsAg;  HBV DNA
分类号:
R446.6
DOI:
-
文献标志码:
A
摘要:
目的 了解驻浙部队乙型肝炎病毒(HBV)感染及低浓度HBsAg流行情况。方法 分层整群抽样6 203名驻浙部队战士和随机抽样2 386名部队干部并采用酶联免疫吸附试验(ELISA)、微粒子酶免疫法(MEIA)、实时荧光聚合酶链反应(PCR)对其血清标本的乙型肝炎病毒标志物(HBV M)、乙型肝炎病毒核酸(HBV DNA)和低浓度HBsAg流行情况进行检测评价。结果 部队战士HBsAg、HBV DNA阳性检出率和HBV DNA对数值分别为0.44%(27/6 203)、44.4%(12/27) 和6.79±1.44，与部队干部HBsAg阳性检出率1.72%(41/2 386)、HBV DNA阳性检出率78.0%(32/41) 和HBV DNA对数值(8.25±1.62)之间的差异具有统计学意义(χ2=36.12, P<0.01;χ2=8.05,P<0.01;t =2.74,P<0.01)；在高、低浓度HBsAg组之间部队战士和干部的HBsAg阳性百分比、HBV DNA对数均值均存在统计学差异(P<0.01~0.05)。结论 部队HBV感染处于低感染、低流行状态，低浓度HBsAg在部队战士中比例较高，应提高征兵体检工作中HBsAg检测质量和同时检测HBV M五项指标；对部队干部的HBV感染应加强监测和防治工作。
Abstract:
ObjectiveTo understand the HBV infection status and epidemiological status of low-level HBsAg in soldiers of PLA stationed in Zhejiang. MethodsA total of 6203 soldiers and 2386 cadres of PLA stationed in Zhejiang were selected in our study by stratified cluster sampling and random sampling, respectively. Serum markers of hepatitis B virus (HBV M), HBV DNA and low-level HBsAg were detected and evaluated by enzyme-linked immunosorbent assay (ELISA), microparticle enzyme immunoassay (MEIA), real-time fluorescence polymerase chain reaction (PCR). ResultsThe positive detection rate of HBsAg，the positive rate of HBV DNA and the logarithmic mean value of HBV DNA were 0.44%(27/6 203), 44.4%(12/27) and 6.79±1.44 in 6203 soldiers, respectively, which were significantly different from 1.72%(41/2 386),78.0%(32/41) and 8.25±1.62 in 2 386 cadres (χ2=36.12, P<0.01;χ2=8.05,P<0.01;t =2.74,P<0.1). There were all statistically significant differences in the positive percentage of HBsAg and the logarithmic mean value of HBV DNA between high- and low-level HBsAg group (P<0.01~0.05). ConclusionsThe HBV infection and epidemiological rate of HBV in soldiers of PLA were low, and the positive rate of low-level HBsAg was much higher in soldiers, so the HBsAg detection quality must be improved in health examination of conscription. The five indexes of HBV markers should be detected, simultaneously. Monitoring, prevention and treatment in routine work must be strengthened to control HBV infection in cadres.

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备注/Memo

备注/Memo:
南京军区医药卫生基金课题(02MB018)
更新日期/Last Update: 2013-11-20