|本期目录/Table of Contents|

[1]李爱梅,郭万华,贾鹏,等.肝癌肝移植术后18F-FDG PET/CT显像特点和预后判断[J].医学研究与战创伤救治(原医学研究生学报),2010,12(05):393-396.
　LI Ai-mei,GUO Wan-hua,JIA Peng,et al.Imaging of 18F-FDG PET/CT and its value in prediction of prognosis in patients with hepatocellular carcinoma after transplantation[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2010,12(05):393-396.
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肝癌肝移植术后18F-FDG PET/CT显像特点和预后判断()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第12卷
期数:
2010年05期
页码:
393-396
栏目:
出版日期:
2010-09-20

文章信息/Info

Title:
Imaging of 18F-FDG PET/CT and its value in prediction of prognosis in patients with hepatocellular carcinoma after transplantation
文章编号:
1672-271X(2010)05-0393-04
作者:
李爱梅; 郭万华; 贾鹏; 申景涛; 张颖
210008 江苏南京，南京大学医学院附属鼓楼医院核医学科
Author(s):
LI Ai-mei; GUO Wan-hua; JIA Peng; SHEN Jing-tao;  ZHANG Ying.
Nuclear Medcine Department of Nanjing Drum Tower Hospital, Nanjing，Jiangsu 210008，China
关键词:
PET/CT; 肝癌; 肝移植; 评估
Keywords:
PET/CT;  hepatocellular carcinoma;  liver transplantation;  assessment
分类号:
R657.3；R814.42
DOI:
-
文献标志码:
A
摘要:
目的 分析肝癌肝移植患者术后18F-FDG(18 氟标记的脱氧葡萄糖)PET/CT的显像特点和预后判断。 方法 回顾分析2006年以来15例已行肝移植的肝癌患者的临床病历资料和18F-FDG PET/CT的影像学资料及随访结果，用Kaplan-Meier方法计算其生存率，COX回归进行预后因素分析。结果 ①15例肝移植患者PET/CT显像中，9例提示肿瘤复发和远处转移，6例为阴性显像。②15例显像分为阳性组(n=9)和阴性组(n=6),中位生存时间为分别为18个月和67个月。③Log-rank单因素分析预后因素年龄、最大标准摄取值(SUVmax)和甲胎蛋白(AFP)水平是影响预后的独立因素。结论 18F-FDG PET/CT对肝癌肝移植患者的全面评估及预后判断具有较好的应用价值。
Abstract:
Objective To analyze 18F-FDG PET/CT imaging of postransplatation and predict prognosis in patients with hepatocellular carcinoma.Methods Clinical data, 18F-FDG PET/CT imaging picture and follow up results of 15 patients who underwent liver transplantation after 2006 were retrospectively analyzed.The cumulative survival was calculated by Kaplan-Meier method.The COX multivariate regression was applied for prognostic factors analysis.Results In 15 patients, tumor recurrence and distant metastases were detected in 9 cases and not detected in 6 cases.The median time of survival was 18 months and 67 months in positive and negative groups.Log-rank analysis showed that the age,SUVmax and alpha protein (AFP) were independent factors for prognosis.Conclusion 18F-FDG PET/CT plays an important role in assessment of postransplatation and prediction of prognosis in patients with hepatocellular cancer.

参考文献/References:

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备注/Memo

备注/Memo:
南京市医学重点科技发展项目(ZKX09019)
更新日期/Last Update: 2010-09-20