|本期目录/Table of Contents|

[1]吴述良,杨小宁,沈根法,等.小剂量瑞芬太尼在全麻苏醒期的应用[J].医学研究与战创伤救治(原医学研究生学报),2011,13(01):42-44.
　WU Shu-liang,YANG Xiao-ning,SHEN Gen-fa,et al.The administration of low-dose remifentanil during emergence from general anesthesia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(01):42-44.
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小剂量瑞芬太尼在全麻苏醒期的应用()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年01期
页码:
42-44
栏目:
出版日期:
2011-01-20

文章信息/Info

Title:
The administration of low-dose remifentanil during emergence from general anesthesia
文章编号:
1672-271X(2011)01-0042-03
作者:
吴述良; 杨小宁; 沈根法; 陶翠萍
243100 安徽当涂，解放军81医院86临床部麻醉科
Author(s):
WU Shu-liang;  YANG Xiao-ning;  SHEN Gen-fa;  TAO Cui-ping
Department of Anesthesiology, No.86 Hospital of PLA, Anhui province, Dangtu, 243100
关键词:
芬太尼; 全麻; 苏醒期
Keywords:
remifentanil;  general anesthesia;  emergence
分类号:
R614.24
DOI:
-
文献标志码:
A
摘要:
目的 探讨在全麻苏醒期输注小剂量瑞芬太尼对患者呛咳反应、不自主运动、平均动脉压和心率的影响。方法 腹腔镜胆囊切除术49例作为研究对象，随机分为观察组25例，对照组24例。观察组于术毕继续输注瑞芬太尼，输注速度调整为术中平均泵注速度的1/10，对照组术毕停止输注瑞芬太尼。结果 两组研究对象清醒时间、拔管时间比较差异无统计学意义(P>0.05)，对照组患者呛咳的发生率及严重程度、不自主运动的发生率均明显高于观察组(P＜0.05)。对照组患者拔管前2 min、拔管后5 min心率明显快于观察组(P<0.05)。结论 输注小剂量瑞芬太尼可减少全麻苏醒期呛咳反应及不自主运动，而不影响全麻苏醒。
Abstract:
Objective To evaluate the effect of maintaining a low-dose remifentanil infusion during emergence on the incidence of coughing, nonpurposeful movement, and hemodynamic disturbances. Methods 49 adult patients undergoing laparoscopic cholecystectomy were divided into test group (25 cases) and control group (24 cases) randomly. The test group patients were administrated to remifentanil after operation. During the emergence phase, the remifentanil reduced to one tenth of the maintenance rate. The control group had remifentanil discontinued. Results Times to awakening and tracheal extubation were no different between two groups (P>0.05). During emergence, the remifentanil group had a significantly lower incidence and less severe coughing (P<0.05), and a lower incidence of nonpurposeful movement and slower heart rates (P<0.05) compared with the control group. Conclusion Low-dose remifentanil during emergence does not prolong wake-up time but reduces the incidence and severity of coughing from the endotracheal tube.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-01-20