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[1]吴建伟,赵 颖,艾书跃,等.PET/CT在探查胃肠道黏液腺癌和印戒细胞癌术后转移中的作用[J].医学研究与战创伤救治(原医学研究生学报),2012,14(02):123-125.
　WU Jian-wei,ZHAO Ying,AI Shu-yue,et al.The role of PET/CT in detecting the metastasis of postoperative gastrointestinal mucinous adenocarcinoma and signet-ring cell carcinoma[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2012,14(02):123-125.
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PET/CT在探查胃肠道黏液腺癌和印戒细胞癌术后转移中的作用()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第14卷
期数:
2012年02期
页码:
123-125
栏目:
出版日期:
2012-03-20

文章信息/Info

Title:
The role of PET/CT in detecting the metastasis of postoperative gastrointestinal mucinous adenocarcinoma and signet-ring cell carcinoma
文章编号:
1672-271X(2012)02-0123-03
作者:
吴建伟; 赵 颖; 艾书跃; 高 红
210002 江苏南京，解放军81医院影像科
Author(s):
WU Jian-wei; ZHAO Ying; AI Shu-yue; GAO Hong.
Imaging Department of 81 Hospital of PLA,Nanjing,Jiangsu 210002,China
关键词:
胃肠道; 黏液腺癌; 印戒细胞癌; 正电子发射断层/计算机断层扫描; 18F-氟代脱氧葡萄糖
Keywords:
gastrointestinal tract;  mucinous adenocarcinoma;  signet-ring cell carcinoma;  PET/CT;  18F-FDG
分类号:
R445
DOI:
-
文献标志码:
A
摘要:
目的 探讨PET/CT在探查胃肠道黏液腺癌和印戒细胞癌术后转移中的作用和限度。方法 对41例胃肠道黏液腺癌和印戒细胞癌术后患者(A组)和51例其他细胞类型的胃肠道癌术后患者(B组)行PET/CT检查。其中36例经再次手术或穿刺等获得病理证实，55例随访6月以上确诊，测量并比较两组转移瘤最大标准摄取值(standard uptake value，SUVmax)，比较PET/CT检查在两组患者中的效用。结果 A组最终确诊31例转移，10例无转移，PET/CT真阳性23例，假阳性1例，真阴性9例，假阴性8例，敏感性和特异性分别为74.2%和90.0%。B组25例阳性，26例阴性，PET/CT检查真阳性为23例，假阳性3例，真阴性为23例，假阴性2例，敏感性和特异性分别为92.0%和88.5%。两组转移瘤SUVmax差异没有统计学意义(P>0.05)。结论 以PET/CT检查胃肠道黏液腺癌和印戒细胞癌术后转移的假阴性高于其他细胞类型的癌，因此结合临床症状和其他检查是十分必要的。
Abstract:
Objective To explore the role and limitation of PET/CT in detecting the postoperative metastasis of gastrointestinal mucinous adenocarcinoma and signet-ring cell carcinoma.Methods PET/CT was performed in 41 patients with gastrointestinal mucinous adenocarcinoma and signet-ring cell carcinoma after operation(A group) and in 51 cases with postoperative gastrointestinal other type cell carcinoma(B group).The final diagnoses were obtained by histopathological verification in 36 cases and by more than 6-months follow-up in 55 patients.The SUVmax of lesions in two groups were measured and the efficiency of PET/CT examination between two groups were compared.Results The final diagnoses in group A included 31 patients with metastases10 patients without metastasis.23 patients with metastasis were confirmed by using PET/CT,one patient was false positive,9 patients were true negative,8 patients were false negative.The sensitivity and specificity of PET/CT were 74.2% and 90.0% respectively.In group B,the metastases were confirmed in 25 cases and no metastasis was in 26 patients.23 cases were confirmed by PET/CT,3 were false positive,23 cases were true negative,2 cases were false negative.The sensitivity and specificity of PET/CT were 92.0% and 88.5% respectively.No statistical differences were found in SUVmax of metastatic lesions between two groups.Conclusion It was necessary to combine the clinical symptoms and other examination in detecting the metastasis of postoperative gastrointestinal mucinous adenocarcinoma and signet-ring cell carcinoma.There is a higher false negative in these patients with examination of PET/CT than in other type cell carcinoma.

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备注/Memo:
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更新日期/Last Update: 2012-03-20