|本期目录/Table of Contents|

[1]舒荣文,顾佳云,孔庆军.枸橼酸铋雷尼替丁为基础治疗萎缩性胃炎患者Hp的疗效观察[J].医学研究与战创伤救治(原医学研究生学报),2013,15(01):27-29.
　SHU Rong-wen,GU Jia-yun,KONG Qing-jun..Observation of curative effect of ranitidine bismuth citrate based triple therapies for eradication of Helicobacter pylori infection in chronic atrophic gastritis patients[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2013,15(01):27-29.
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枸橼酸铋雷尼替丁为基础治疗萎缩性胃炎患者Hp的疗效观察()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第15卷
期数:
2013年01期
页码:
27-29
栏目:
出版日期:
2013-01-20

文章信息/Info

Title:
Observation of curative effect of ranitidine bismuth citrate based triple therapies for eradication of Helicobacter pylori infection in chronic atrophic gastritis patients
文章编号:
1672-271X(2013)01-0027-03
作者:
舒荣文; 顾佳云; 孔庆军
210024 江苏南京，南京军区南京总医院干部保健科
Author(s):
SHU Rong-wen; GU Jia-yun; KONG Qing-jun.
Department of Healthcare for Senior Officers,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu 210002,China
关键词:
枸橼酸铋雷尼替丁; 三联疗法; 幽门螺杆菌; 萎缩性胃炎
Keywords:
ran ranitidine bismuth citrate; triple therapies; helicobacter pylori(Hp); atrophic gastritis
分类号:
R573.32
DOI:
-
文献标志码:
A
摘要:
目的 应用枸橼酸铋雷尼替丁(RBC)与克拉霉素+阿莫西林三联7d疗法根除幽门螺杆菌(Hp)，评估以RBC为基础的三联方案的疗效。方法 萎缩性胃炎120例随机分为R组和O组，每组60例，R组为RBC 350 mg+克拉霉素0．5 g+阿莫西林1 g，2次/d，口服；O组为奥美拉唑(OME) 20 mg+克拉霉素0.5 g+阿莫西林1 g，2次/d，口服，疗程均为7 d。停药28 d后检查14C尿素呼气试验，如阴性表示根除成功，观察两组Hp阴转率。结果 两组Hp阴转率分别为83.02%和71.15%，差异无统计学意义(P>0.05)。结论 R组根除萎缩性胃炎患者Hp感染，其Hp阴转率与O组相当。
Abstract:
Objective To compare the eradication rates in helicobacter pylori(Hp) infection of two triple therapies.Methods One hundred and twenty patients with chronic atrophic gastritis were randomized into two groups.Group R was given with ranitidine bismuth citrate(RBC) 350 mg bid plus clarithromycin 0.5 g bid and amoxicillin 1.0 g bid pofor one week.Group O was treated with omeprazole 20 mg bid plus clarithromycin 0.5 g bid and amoxicillin 1.0 g bid pofor one week.Rapid urease test was repeated one month after anti-HP therapy.Results The eradiation rates of group Rand group O were 83.02% and 71.15%,respectively.No significant difference was found between two groups (P>0.05).Conclusion The regimen of triple therapy with RBC is good as regimen with OME for the clinical eradication of Hp infection.

参考文献/References:

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更新日期/Last Update: 2013-01-20