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[1]余志阳,郑大东,杭太香,等.Narcotrend监测技术在无痛结肠镜检查中的应用[J].医学研究与战创伤救治(原医学研究生学报),2013,15(03):221-223.[doi:10.3969/j.issn.1672-271X.2013.03.005]
　YU Zhi-yang,ZHENG Da-dong,HANG Tai-xiang,et al.Clinical study on narcotrend monitoring used for no pain-anesthesia during colonoscopy in patient[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2013,15(03):221-223.[doi:10.3969/j.issn.1672-271X.2013.03.005]
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Narcotrend监测技术在无痛结肠镜检查中的应用()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第15卷
期数:
2013年03期
页码:
221-223
栏目:
出版日期:
2013-03-30

文章信息/Info

Title:
Clinical study on narcotrend monitoring used for no pain-anesthesia during colonoscopy in patient
作者:
余志阳1; 郑大东2; 杭太香1; 徐苗苗1; 李伟彦1; 潘士勇2; 诸葛海鸿1; 朱四海1
210002 江苏南京,南京军区南京总医院,1.麻醉科,2.干部保健科
Author(s):
YU Zhi-yang1; ZHENG Da-dong2; HANG Tai-xiang1; XU Miao-miao1; LI Wei-yan1; PAN Shi-yong2; ZHU-GE Hai-hong1; ZHU Si-hai1
1.Department of Anesthesiology,2.Department of Ranking Health Protection,Nanjing General Hospital of Nanjing Military Command,Nanjing 210002,Jiangsu,China
关键词:
麻醉脑电意识深度监测系统; 结肠镜; 丙泊酚; 麻醉深度
Keywords:
Narcotrend;  colonoscopy;  propofol;  depth of anesthesia
分类号:
R614.2
DOI:
10.3969/j.issn.1672-271X.2013.03.005
文献标志码:
A
摘要:
目的 探讨在无痛结肠镜检查中使用Narcotrend麻醉脑电意识深度监测系统监测丙泊酚全凭静脉麻醉时麻醉深度,评估丙泊酚应用的有效性、安全性,确立无痛结肠镜检查时恰当的Narcotrend数值(NI)范围以指导临床。方法 无痛结肠镜检查150例,根据NI值随丙泊酚输入剂量的变化分为3组,每组50例。A组NI=35～45,B组NI=46～56,C组NI=57～67。记录检查过程中生命体征、呛咳体动反应、反流误吸、结肠镜检查时间、苏醒时间、丙泊酚用量。结果 丙泊酚用量A组明显高于B组和C组(P<0.01); A组苏醒时间高于B组和C组(P<0.05); B组检查过程中发生不良反应仅为8%,低于A组(24%)和C组(16%)(P<0.05)。结论 Narcotrend可以指导监测无痛结肠镜检查的麻醉深度,NI值在46～56具有较高的安全性及有效性。
Abstract:
Objective To investigate the depth of anesthesia of propofol monitored by using narcotrend in no pain-anesthesia during colonoscopy,assessing its clinical safety,efficacy in order to establish the appropriate range of Narcotrend index(NI)in a painless colonoscopy,and serve as a clinical guidance.Methods One hundred fifty patients undergoing painless colonoscopy were enrolled.All patients were randomly divided into three groups according to NI with different dose of propofol infusion,there were fifty patients in each groups(Group A:NI =35-45,Group B NI=46-56,Group C NI=57-67).Record the vital signs,adverse reactions including cough,body movement,regurgitation,aspiration,and the operation time.The recovery time and the dose of propofol were also recorded.Results The patients in Group A had the longest time to wake up and consumed the largest dose of propofol(P<0.01).With all the three groups,adverse reactions in Group B were only 8%,and were lower than that in Group A(24%)and Group C(16%)(P<0.05).Conclusion Narcotrend can predict the depth of anesthesia in no pain-anesthesia during colonoscopy,with NI between 46 and 56 have more safety and efficacy.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目: 南京军区面上课题(12MA091)
更新日期/Last Update: 2013-05-20