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[1]陈兴东,万婷婷,李 茜,等.地佐辛与曲马多治疗剖宫产术中寒战的对比研究[J].医学研究与战创伤救治(原医学研究生学报),2013,15(03):249-251.[doi:10.3969/j.issn.1672-271X.2013.03.014]
　CHEN Xing-dong,WAN Ting-ting,LI Qian,et al.Comparison of dezocineand tramadol on shivering during cesaearn section surgery under combined-spinal epidural anaesthesia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2013,15(03):249-251.[doi:10.3969/j.issn.1672-271X.2013.03.014]
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地佐辛与曲马多治疗剖宫产术中寒战的对比研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第15卷
期数:
2013年03期
页码:
249-251
栏目:
出版日期:
2013-03-30

文章信息/Info

Title:
Comparison of dezocineand tramadol on shivering during cesaearn section surgery under combined-spinal epidural anaesthesia
作者:
陈兴东1; 万婷婷2; 李 茜1; 段满林2; 李伟彦2
1.211131 江苏南京,南京军区南京总医院疗养区; 2.210002 江苏南京,南京军区南京总医院麻醉科
Author(s):
CHEN Xing-dong1; WAN Ting-ting2; LI Qian1; DUAN Man-lin2; LI Wei-yan2
1.Sanitarial District,2.Department of Anesthesiology,Nanjing General Hospital of Nanjing Military Command,Nanjing,Jiangsu 210002,China
关键词:
地佐辛; 曲马多; 剖宫产; 寒战; 腰硬联合麻醉
Keywords:
dezocine;  tranmdol;  shivering;  cesaearn section;  combined-spinal epidural anaesthesia
分类号:
R713.14
DOI:
10.3969/j.issn.1672-271X.2013.03.014
文献标志码:
A
摘要:
目的 比较地佐辛与曲马多在治疗剖宫产术中寒战的效果。方法 选择在腰硬联合麻醉后发生寒战的剖宫产手术患者60例,随机分为地佐辛组(D组,0.1 mg/kg)、曲马多组(T组,1 mg/kg),每组30例,均在胎儿娩出后,用生理盐水分别稀释药物至10 ml静脉注入,比较两组治疗寒战的疗效、术中镇静情况及不良反应,并监测平均动脉压(MAP)、脉搏氧饱和度(SpO2)变化。结果 两组患者术中生命体征平稳,两组治疗寒战疗效比较差异无统计学意义(P>0.05); D组Ramsay评分≥3分者15例(50%),T组Ramsay评分≥3分者3例(10%),两者比较差异有统计学意义(P<0.01)。D组无恶心呕吐发生,T组有13例(43%),两组比较差异有统计学意义(P<0.01)。结论 地佐辛治疗产妇腰硬联合麻醉后镇静评分和恶心、呕吐发生优于曲马多 。
Abstract:
Objective To compare the effects of dezocineand tramadol on shivering during cesaearn section surgery under combined-spinal epidural anaesthesia.Methods In this prospective and randomized study,sixty patients who shivered during cesaearn section surgery under combined-spinal epidural anaesthesia(CSEA)were randomly divided into two groups:group D was treated with dezocine(0.1 mg/kg,iv,n=30),group T was treated with tramadol(1mg/kg,iv,n=30).The drug should be given all by venousinjection after childbirth and diluted to 10 milliliter with 0.9%NaCl.The therapeutic effects and adverse effects were observed.Ramsay sedation score,mean arterial pressure(MAP),saturation of pulse oxygen(SpO2)were recorded.Results There was no significant difference between the two groups with respect to MAP,SpO2,or intensity of shivering after treatment.The number of patients whose ramsay sedation score≥3 were different between the two groups(15 VS 3,P<0.01).There was no vomiting in group D while 13 cases in group T(P<0.01).Conclusion Dezocine is better than tranmdol when treating shivering in cesaearn section under combined spinal epidural anaesthesia with few adverse effects such as nausea and vomiting.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-05-20