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[1]葛明盖,于 倩,张同梅,等.17例白色萎缩临床病理分析并治疗探讨[J].医学研究与战创伤救治(原医学研究生学报),2015,17(02):152-153，193.[doi:10.3969/j.issn.1672-271X.2015.02.012]
　GE Ming-gai,YU Qian,ZHANG Tong-mei,et al.Analysis and treatment of 17 cases of atrophic blanche[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(02):152-153，193.[doi:10.3969/j.issn.1672-271X.2015.02.012]
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17例白色萎缩临床病理分析并治疗探讨()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年02期
页码:
152-153，193
栏目:
出版日期:
2015-04-22

文章信息/Info

Title:
Analysis and treatment of 17 cases of atrophic blanche
作者:
葛明盖; 于 倩; 张同梅; 毕新岭; 顾 军
200433 上海，第二军医大学附属长海医院皮肤科
Author(s):
GE Ming-gai;  YU Qian;  ZHANG Tong-mei;  BI Xin-ling;  GU Jun.
Department of Dermatology， Changhai Hospital， Second Military Medical University， Shanghai 200433， China
关键词:
白色萎缩; 青斑血管病变; 利伐沙班
Keywords:
atrophy blanche;  livedoid vasculopath;  rivaroxaban
分类号:
R758.6
DOI:
10.3969/j.issn.1672-271X.2015.02.012
文献标志码:
A
摘要:
目的 提高对白色萎缩早期诊断能力和发病机制的认识，探讨有效的治疗方法。方法 对第二军医大学附属长海医院2005-2014年诊治的白色萎缩17例的临床资料进行回顾性分析，包括临床、病理及不同的治疗方法与效果。结果多见于青年女性，皮损好发于下肢；15例血管腔内有透明血栓形成(占88.2％)；双嘧达莫及达那唑、利伐沙班治疗效果较好；早期误诊9例(占52.9％)。结论 临床特点及早期的组织病理学检查为诊断本病的依据，医务人员应加强对早期白色萎缩的认识，利伐沙班可能有助于该病的治疗和减少复发。
Abstract:
Objective To analyse clinical and pathological presentation of 17 cases of atrophic blanche and to discuss the result of the treatment.Methods A retrospective analysis of the clinica1 data from 17 patients with this disorder in changhai hospital， data including clinical and pathological presentation and treatment． Results The disease was mostly seen in young women of the lower extremities.15 of 17 patients (88.2％) had thrombus formation in the lumen of blood vessels． The good choice of treatment is use of dipyridamole combined with rivaroxaban and danazol． 9 cases of misdiagnosis of the disease， the rate of early misdiagnosis about 52.9%． Conclusion The diagnosis of this disorder is mainly dependent on clinical features and histopathologic changes.Medical personnel should be alerted to the diagnosis of atrophic blanche.Rivaroxaban may be helpful to treat the disease and reduce its relapse.

参考文献/References:

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更新日期/Last Update: 2015-03-20