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[1]卢海波,朱 丽,钟 晶,等.纵隔神经内分泌癌的影像学表现[J].医学研究与战创伤救治(原医学研究生学报),2015,17(03):253.[doi:10.3969/j.issn.1672-271X.2015.03.009]
　LU Hai-bo,ZHU Li,ZHONG Jing,et al.Imaging features of mediastinal neuroendocrine carcinoma[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(03):253.[doi:10.3969/j.issn.1672-271X.2015.03.009]
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纵隔神经内分泌癌的影像学表现()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年03期
页码:
253
栏目:
出版日期:
2015-05-20

文章信息/Info

Title:
Imaging features of mediastinal neuroendocrine carcinoma
作者:
卢海波1; 朱 丽2; 钟 晶1; 吴建伟1
1.210002 江苏南京，解放军81医院影像科；2.212001 江苏镇江，江苏大学附属医院影像科
Author(s):
LU Hai-bo1;  ZHU Li2;  ZHONG Jing1;  WU Jian-wei1.
1.Department of Imaging， 81 Hospital of PLA， Nanjing， Jiangsu 210002， China； 2.Department of Imaging， the Affiliated Hospital of Jiangsu University， Zhenjiang， Jiangsu 212001， China
关键词:
神经内分泌癌; X-线计算机断层; 磁共振成像; 正电子发射断层/X-线计算机断层
Keywords:
neuroendocrine carcinoma;  X-ray computed tomography;  magnetic resonance imaging;  positron emission tomography/computed tomography
分类号:
R734.5
DOI:
10.3969/j.issn.1672-271X.2015.03.009
文献标志码:
A
摘要:
目的 分析纵隔神经内分泌癌的影像学特点及临床应用。方法 回顾性分析经病理证实的5例纵隔神经内分泌癌的CT、MRI以及PET/CT征象，以便对肿瘤临床分期以及制定治疗方案提供信息。结果 5例纵隔神经内分泌癌分别位于前纵隔2例、中纵隔2例、后纵隔1例。其中4例呈浸润性生长、包绕周围血管，1例位于隆突下呈膨胀性生长；4例CT检查呈中度强化。1例在MRI上呈不均匀性较长T1较长T2信号，3例行18F-PET-CT检查，最大摄取值中位数（SUVmax）为9.2（6.7～28.5）。本组5个病例全部发生远处转移，肿瘤分期均为Ⅳ期，并接受放化疗。结论 纵隔神经内分泌癌呈浸润性生长、不均匀软组织密度或信号、中度对比增强、易转移、糖代谢明显增高等特点，影像检查有利于肿瘤分期和制订治疗方案。
Abstract:
Objective To analyze the imaging characteristics of mediastinal neuroendocrine carcinoma and their clinical application. Methods In 5 patients， the imaging findings of mediastinal neuroendocrine carcinoma confirmed by pathology on CT， MR and PET/CT were analyzed retrospectively to perform the clinical staging and determine the therapeutic plans. Results Of total 5 cases of mediastinal neuroendocrine carcinoma， 2 were located in anterior mediastinum， 2 in middle mediastinum and 1 in posterior mediastinum. The lesions presented infiltrative growth wrapping around the blood vessel in 4 cases and expansive growth at the subcarinal in 1 patients. The lesions showed moderate enhancement on contrast CT in 4 cases and heterogeneous long T1 and long T2 signal on MRI in 1 case. The media of maximal standard uptake value (SUVmax) was 9.2(6.7-28.5) on 18F-FDG PET/CT. In all 5 cases， the metastases were found that were defined as stage Ⅳ and chemoradiation were performed. Conclusion Mediastinal neuroendocrine carcinoma presented infiltrative growth， heterogeneous density or signal intensity， moderate enhancement， easy metastasis， and higher glycometabolism， which was in favour of neoplasm staging and determination of treatment protocol.

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更新日期/Last Update: 2015-05-20