|本期目录/Table of Contents|

[1]孙青青,周爱萍.持续被动运动对兔膝关节损伤后侧副韧带内弹性蛋白表达的影响[J].医学研究与战创伤救治(原医学研究生学报),2015,17(05):487-489.[doi:10.3969/j.issn.1672-271X.2015.05.012]
　SUN Qing-qing,ZHOU Ai-ping..Continuous passive motion had an influence on elastic protein expression in deputy ligament after rabbits knee injury[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(05):487-489.[doi:10.3969/j.issn.1672-271X.2015.05.012]
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持续被动运动对兔膝关节损伤后侧副韧带内弹性蛋白表达的影响()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年05期
页码:
487-489
栏目:
出版日期:
2015-09-30

文章信息/Info

Title:
Continuous passive motion had an influence on elastic protein expression in deputy ligament after rabbits knee injury
作者:
孙青青1; 周爱萍2
1.233030 安徽蚌埠，蚌埠医学院研究生部2013级研究生（解放军82医院）； 2.223001 江苏淮安，解放军82医院医疗质量控制科
Author(s):
SUN Qing-qing1;  ZHOU Ai-ping2.
1.Bengbu Medical University， Beng’bu， Anhui 233030， China； 2.Department of Medical Quality Control， 82 Hospital of PLA ， Huai’an， Jiangsu 223001， China
关键词:
兔; 持续被动运动; 膝关节损伤; 弹性蛋白; 蛋白印迹
Keywords:
rabbit;  continuous passive motion;  knee injury;  elastin;  western blotting
分类号:
R3；R686.5
DOI:
10.3969/j.issn.1672-271X.2015.05.012
文献标志码:
A
摘要:
目的 观察持续被动运动（continuous passive motion，CPM）对兔膝关节损伤后侧副韧带内弹性蛋白的影响。方法 选取15只新西兰雄性大白兔造膝关节软骨全层 缺损模型，术后按运动方式不同，随机分成3组即制动组、自由活动组，CPM组。6周后提取韧带采用蛋白免疫印迹法（western blotting）进行弹性蛋白的检测。结果 制动组的膝 关节出现不同程度的僵硬，功能出现障碍；三组弹性蛋白的表达量分别是制动组（0.84±0.25）、自由活动组（2.91±0.34）、CPM组（2.04±0.69）。自由活动组侧副韧带内弹性 蛋白的表达高于制动组和CPM组，CPM组侧副韧带内弹性蛋白的表达高于制动组，差异均有统计学意义（P＜0.01）。结论 CPM和自由活动均可有效防止关节损伤后导致的韧带挛缩 及关节僵硬，而自由活动效果更好。
Abstract:
Objective Observe the influence of elastin in the deputy ligament of rabbit whose knee joint were injury after continuous passive motion. Methods 15 male New Zealand rabbits were used to establish the model of knee joint cartilage full-thickness defect. Then according to different way of movement， all animals were randomly divided into 3 groups： brake group， free activity group， CPM group. Ligaments were extracted and the elastin was test by western blot. Results All rabbits knee joint appeared stiffness in different degrees and functional bottleneck. The elastin expression of three groups are as follows： brake group (0.84±0.25)， free activity group (2.91±0.34)， CPM group (2.04±0.69). Elastin expression of the deputy ligament in free activity group was higher than the brake group and CPM group (P＜0.01). Elastin expression of the deputy ligament in CPM group was higher than the brake group (P＜0.01). Conclusion CPM and free activities could effectively prevent ligament contracture and stiffness of joint which is caused by joint damage， while free activities is better.

参考文献/References:

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备注/Memo

备注/Memo:
蚌埠医学院研究生科技创新立项课题（Byycx1420）
更新日期/Last Update: 2015-09-20