|本期目录/Table of Contents|

[1]徐成润 综述,伍伟平 审校.PD-1/PD-L1负性协同刺激通路在乙型病毒性肝炎慢性化中的地位及进展[J].医学研究与战创伤救治(原医学研究生学报),2015,17(05):514-516,523.[doi:10.3969/j.issn.1672-271X.2015.05.021]
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PD-1/PD-L1负性协同刺激通路在乙型病毒性肝炎慢性化中的地位及进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年05期
页码:
514-516,523
栏目:
综述
出版日期:
2015-09-30

文章信息/Info

Title:
-
作者:
徐成润 综述伍伟平 审校
363000 福建漳州,厦门大学附属东南医院感染科
Author(s):
-
关键词:
PD-1/PD-L1通路肝炎乙型慢性
Keywords:
-
分类号:
R512.62
DOI:
10.3969/j.issn.1672-271X.2015.05.021
文献标志码:
A
摘要:
乙型肝炎是影响我国人群健康的主要疾病之一,乙型肝炎病毒(hepatitis B virus,HBV)的慢性感染可导致疾病的进展。现有研究提示细胞程序性死亡因子-1/细胞 程序性死亡因子配体(PD-1/PD-L1)通路可减弱T细胞的免疫功能,从而导致疾病的慢性化及重症化。目前有关PD-1/PD-L1通路在慢性乙型肝炎疾病进展中的作用未有系统的阐述。 本文就PD-1/PD-L1通路与免疫调节在慢性乙型肝炎中的作用进行综述,为临床疾病预后的判断提供参考。
Abstract:
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参考文献/References:

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更新日期/Last Update: 2015-09-20