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[1]王苏,郭华,赵颖,等.Omega-3多不饱和脂肪酸对颈胸腹三切口食管癌切除术后炎症反应的影响研究[J].医学研究与战创伤救治(原医学研究生学报),2016,18(05):501-504.[doi:10.3969/j.issn.1672-271X.2016.05.016]
　WANG Su,GUO Hua,ZHAO Ying,et al.The effect of ω-3 fish oil fatty emulsion on inflammatory reaction indicators in cervico-right thoracic-abdominal triple incision (McKeown surgery) esophageal carcinoma resection[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(05):501-504.[doi:10.3969/j.issn.1672-271X.2016.05.016]
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Omega-3多不饱和脂肪酸对颈胸腹三切口食管癌切除术后炎症反应的影响研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第18卷
期数:
2016年05期
页码:
501-504
栏目:
出版日期:
2016-09-20

文章信息/Info

Title:
The effect of ω-3 fish oil fatty emulsion on inflammatory reaction indicators in cervico-right thoracic-abdominal triple incision (McKeown surgery) esophageal carcinoma resection
作者:
王苏1; 郭华2; 赵颖3; 樊睿杰2; 董兵1
1.100017北京，解放军305医院胸心外科;2.332000江西九江，解放军171医院胸心外科;3.518020广东深圳，深圳市人民医院外科重症监护室
Author(s):
WANG Su1;  GUO Hua2;  ZHAO Ying3;  FAN Rui-jie2;  DONG Bing1
1. Department of Cardiothoracic Surgery,305 Hospital of PLA, Beijing 100017，China;2. Department of Cardiothoracic Surgery,171 Hospital of PLA, Jiujiang, Jiangxi 332000，China;3. Surgical Intensive Care Unit of Shenzhen People’s Hospital, Shenzhen, Guangdon
关键词:
食管癌; Omega-3多不饱和脂肪酸; 白细胞介素-6
Keywords:
esophageal carcinoma;  ω-3 fish oil fatty emulsion;  IL-6
分类号:
R453.9
DOI:
10.3969/j.issn.1672-271X.2016.05.016
文献标志码:
A
摘要:
目的 明确Omega-3多不饱和脂肪酸对颈胸腹三切口食管癌术后炎症反应的影响。方法 将44例颈胸腹三切口食管癌手术患者随机分为干预组(21例)和对照组(23例)。术后肠内营养支持方案对照组给予中长链脂肪乳剂, 干预组加用Omega-3鱼油脂肪乳剂, 其他治疗措施相同。观察患者术后一般情况，检测C-反应蛋白(CRP)、白细胞总数（WBC）、APACHE Ⅱ评分及血浆白细胞介素-6(IL-6)浓度水平。结果 两组患者在术中术后一般情况、WBC、CRP及APACHE Ⅱ评分上差异均无统计学意义(P＞0.05)。Omega-3多不饱和脂肪酸组患者在术后第2天及第3天IL-6低于对照组，差异有统计学意义（P＜0.05)。结论 在颈胸腹三切口食管癌手术中, Omega-3多不饱和脂肪酸能够有效降低颈胸腹三切口食管癌术后IL-6水平。
Abstract:
Objective To evaluate the impact of ω-3 fish oil fatty emulsion on inflammatory reaction indicators in cervico-right thoracic-abdominal triple incision (McKeown surgery) esophageal carcinoma resection. Methods A total of 44 patients who undergo McKeown surgery were randomly assigned to two groups：the FO group (n=21) and the control group (n=23). In the first 3 days after operation, the control group was given MCT/LCT liquid emulsion. The patients in FO group was administered ω-3 fish oil fatty emulsion additionally. The general status, CRP, WBC, APACHE II and IL-6 were detected and analysed. Results It showed no significant difference between the general status, CRP, WBC, APACHE II(P>0.05).The plasma IL-6 concentration was significantly lower in the trial group than the control group on D2 and D3(P<0.05). Conclusion ω-3 fish oil fatty emulsion can significantly reduce the concentration of IL-6 in McKeown surgery.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2016-12-09