|本期目录/Table of Contents|

[1]曹昌魁,曹丽萍,顾旭东,等.早期行肠内营养在重症胰腺炎治疗中的作用[J].医学研究与战创伤救治(原医学研究生学报),2016,18(06):569-571.[doi:10.3969/j.issn.1672-271X.2016.06.003]
 CAO Chang-kui,CAO Li-ping,GU Xu-dong,et al.Study of early enteral nutrition therapy in patients with acute severe pancreatitis[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(06):569-571.[doi:10.3969/j.issn.1672-271X.2016.06.003]
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早期行肠内营养在重症胰腺炎治疗中的作用()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第18卷
期数:
2016年06期
页码:
569-571
栏目:
出版日期:
2016-11-20

文章信息/Info

Title:
Study of early enteral nutrition therapy in patients with acute severe pancreatitis
作者:
曹昌魁曹丽萍顾旭东聂时南
210002江苏南京,南京军区南京总医院(南京大学医学院附属金陵医院)急救医学科
Author(s):
CAO Chang-kui CAO Li-ping GU Xu-dong NIE Shi-nan.
Department of Emergency Medicine, Nanjing General Hospital of Nanjing Military Command, PLA/Jingling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China
关键词:
肠内营养重症胰腺炎APACHEⅡ评分
Keywords:
enteral nutrition severe pancreatitis APACHEⅡ score
分类号:
R576
DOI:
10.3969/j.issn.1672-271X.2016.06.003
文献标志码:
A
摘要:
目的 探讨早期行肠内营养在重症胰腺炎治疗中的作用。方法 收集2013年1月-2015年2月在南京军区南京总医院急救医学科收治的58例重症胰腺炎患者病例资料,按照随机数字表法随机分成采 用早期肠内营养治疗组(观察组)和采用常规治疗组(对照组)各29例。比较两组患者治疗前和治疗后3周时的APACHEⅡ评分、前清蛋白与血清清蛋白的差异。结果 两组患者治疗前APACHEⅡ评分均值差 异无统计学意义(P>0.05),观察组重症胰腺炎患者治疗后3周时APACHEⅡ评分结果明显低于对照组[(1.7±0.4)分vs.(3.0±0.9)分](P<0.05);观察组治疗后3周时前清蛋白含量均值为(263.5± 11.4)mg/L,明显高于对照组患者含量水平(200.9±15.8)mg/L(P<0.05),与此同时,两组重症胰腺炎患者治疗后3周时血清清蛋白含量水平差异具有统计学意义[(34.1±2.5)g/L vs.(31.5±3.0 )g/L](P<0.05)。结论 早期行肠内营养对于改善重症胰腺炎患者的病情具有重要的临床意义。
Abstract:
Objective To investigate the effect of early enteral nutrition therapy in acute severe pancreatitis patients. Methods Data of acute severe pancreatitis patients treated in Emergency Medicine Department of Nanjing General Hospital of Nanjing Military Command from January 2013 to February 2015 were collected. A total of 58 cases were randomly divided into the early enteral nutrition in treatment group (observation group) and the conventional treatment group (control group) according to randomized digital table. The APACHEⅡ scores, serum albumin and pre-albumin between before and after treatment for 3 weeks of two groups of patients were compared. Results There was no significant difference on APACHEⅡ scoring average between the two groups before treatment (P>0.05). APACHEⅡ scores of the observation group three weeks after treatment were obviously lower than the control group [(1.7±0.4) vs. (3.0±0.9)] (P<0.05); The average of pre-albumin in the observation group was(263.5±11.4)mg/L, and the values was significantly higher than those in the control group(200.9±15.8)mg/L. Meanwhile, three weeks after treatment, albumin of the two groups was statistically significant [(34.1± 2.5)g/L vs. (31.5±3.0)g/L] (P<0.05). Conclusion Early enteral nutrition is important for improving the condition of patients with severe pancreatitis.

参考文献/References:

[1]Mounzor R, Langmead CJ, Wu B, et al. Comparison of existing clinicalscoring system to predict persistent organ failure in patient with acute pancreatitis [J].Gastroenterology,2012,142:1476-148.
[2]Li JN, Lai YM, Qian JM, et al. Trends in etiologies of chronic pancreatitis within 20 years: analysis of 636 cases[J]. Chin Med J (Engl), 2011,124(21):3556-3559.
[3]Zhao ZC, Zheng SS, Cheng WL,et al.Suppressing progress of pancreatitis through selective inhibition of NF-κB activation by using NAC[J]. J Zhejiang Univ Sci,2004,5 (4):477-482.
[4]Mohseni Salehi Monfared SS, Vahidi H, Abdolghaffari AH,et al. Antioxidant therapy in the management of acute, chronic and post-ERCP pancreatitis: A systematic review[J]. World J Gastroenterol,2009,15(36):4481-4490.
[5]Niu XK, Das SK, Bhetuwal A,et al. Value of diffusion-weighted imaging in distinguishing pancreatic carcinoma from mass-forming chronic pancreatitis: a meta-analysis[J]. Chin Med J (Engl),2014,127(19):3477-3482.
[6]陈健,王磊,李炳庆,等.肠内营养支持治疗对急性重症胰腺炎肠黏膜屏障功能及细菌移位的影响[J].中国老年学杂志,2014,34(12):3325-3326.
[7]雷荣兰,唐伟,高明焕,等.重症胰腺炎患者肠内营养的护理[J].护士进修杂志,2014,29(4):383-384.
[8]李云莉,张秦,管群,等.26例妊娠合并急性胰腺炎患者的诊治[J].医学研究生学报,2012,25(5):496-498.
[9]高晓燕.空肠内营养与全胃肠外营养对重症急性胰腺炎患者临床疗效及免疫功能的影响[J].中国全科医学,2013,16(29):3486-3487.
[10]黄迎春,张婷婷,李幼生,等.肠内外联合营养支持在放射性肠炎治疗中的效果观察[J].医学研究生学报,2013,26(8):810-812.
[11]王晨光,傅芬兰,刘巧云,等.全胃切除术后早期肠内外营养的临床研究[J].东南国防医药,2013,15(1):30-32.
[12]马克强,高春江,汪志强,等.早期经口进食进行肠内营养在治疗急性重症胰腺炎中的作用[J].重庆医学,2015,44(7):965-967.
[13]张吉香.鼻肠管在急性重症胰腺炎肠内营养中的应用及护理[J].护士进修杂志,2014,29(10):950-951.

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备注/Memo

备注/Memo:
全军后勤面上项目(CNJ14L002);南京军区重点课题(12Z32)
更新日期/Last Update: 2016-11-20