|本期目录/Table of Contents|

[1]燕朝均,于凤旭,廖斌.血清尿酸与风湿性心脏病患者心房颤动的关系[J].医学研究与战创伤救治(原医学研究生学报),2017,19(03):293-297.[doi:10.3969/j.issn.1672-271X.2017.03.018]
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血清尿酸与风湿性心脏病患者心房颤动的关系()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第19卷
期数:
2017年03期
页码:
293-297
栏目:
出版日期:
2017-05-20

文章信息/Info

Title:
-
作者:
燕朝均于凤旭廖斌
作者单位:646000泸州,西南医科大学附属医院胸心外科
Author(s):
-
关键词:
血清尿酸风湿性心脏病心房颤动
Keywords:
-
分类号:
R605;R453
DOI:
10.3969/j.issn.1672-271X.2017.03.018
文献标志码:
B
摘要:
目的 通过分析风湿性心脏病(风心病)合并心房颤动(房颤)患者的血清尿酸水平(尿酸),探讨血清尿酸水平与风湿性心脏病患者心房颤动的关系。方法 回顾性分析334例住院的风湿性心脏病患者,根据有无房颤分为风心病房颤组(240例)、风心病窦性心律组(94例),比较2组的一般资料、临床资料、心脏彩超数据。结果 风心病伴房颤组的血清尿酸、肌酐、尿素、左心房内径(LAD)均明显高于风心病窦性心律组(P<0.05),白蛋白、高密度脂蛋白胆固醇、总胆固醇、性别比例、左心室射血分数(LVEF)均明显低于风心病窦性心律组(P<0.05)。逐步logistic回归分析矫正了尿酸、肌酐、尿素、LAD、性别比例、白蛋白、高密度脂蛋白胆固醇、总胆固醇及LVEF的影响后,尿酸(OR:1.008;95%CI:1.004~1.012;P<0.001)、肌酐(OR:1.038;95%CI:1.008~1.070;P=0.012)、左心房内径(OR:1.040;95%CI:1.006~1.075;P=0.019)、左心室射血分数(OR:0.952;95%CI:0.909~0.998;P=0.040 )与风心病患者房颤的发生显著相关。结论 血清尿酸水平升高是风湿性心脏病患者心房颤动发生的高危险因素,重视早期控制尿酸水平,对预防心房重塑及房颤的发生和发展有一定的临床指导作用。
Abstract:
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参考文献/References:

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备注/Memo

备注/Memo:
基金项目:四川省科技厅项目(Z14018)
更新日期/Last Update: 2017-05-20