|本期目录/Table of Contents|

[1]戴少彬,赖燕云,黄琪玲,等.罗哌卡因蛛网膜下腔阻滞对超高龄髋关节患者术后认知功能的影响[J].医学研究与战创伤救治(原医学研究生学报),2017,19(06):633-635.[doi:10.3969/j.issn.1672-271X.2017.06.018]
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罗哌卡因蛛网膜下腔阻滞对超高龄髋关节患者术后认知功能的影响()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第19卷
期数:
2017年06期
页码:
633-635
栏目:
出版日期:
2017-11-23

文章信息/Info

Title:
-
作者:
戴少彬赖燕云黄琪玲郑惠云查本俊
作者单位:362000泉州,解放军第180医院,1.骨科,2.麻醉科
Author(s):
-
关键词:
罗哌卡因蛛网膜下腔阻滞高龄患者认知功能
Keywords:
-
分类号:
R614.4+1
DOI:
10.3969/j.issn.1672-271X.2017.06.018
文献标志码:
B
摘要:
目的评价等容积不同浓度罗哌卡因蛛网膜下腔阻滞对超高龄髋关节患者术后认知功能的影响。方法选择解放军第180医院骨科2015年1月至2017年2月ASA分级Ⅱ或Ⅲ级,年龄≥80岁的髋关节手术患者100例。采用随机数字表法将其分为2组:0.5%罗哌卡因蛛网膜下腔阻滞组(A组,n=50)和0.33%罗哌卡因蛛网膜下腔阻滞组(B组,n=50),分别给予0.5%和0.33%盐酸罗哌卡因注射液2mL,给药速度均为10~15 s/mL。记录患者术中和术后相关情况,并记录术前、术后24h、术后48h、术后72h时VAS评分、认知功能评分和血浆S100β淀粉样蛋白浓度。结果A组低血压发生率明显高于B组(P<0.05);B组MMSE评分和S100β淀粉样蛋白浓度在术后24h、术后48h均明显高于A组(P<0.05),但术前、术后72h组间比较差异均无统计学意义(P>0.05);A组在术后24h、术后48h MMSE评分和S100β淀粉样蛋白浓度均明显低于术前(P<0.05),而术后72h与术前比较差异均无统计学意义(P>0.05),B组在术后24h MMSE评分和S100β淀粉样蛋白浓度均明显低于术前(P<0.05),而术后48h、术后72h与术前比较差异均无统计学意义(P>0.05)。结论在超高龄髋部手术患者中,应用0.5%罗哌卡因2 mL较0.33%罗哌卡因2mL进行蛛网膜下腔阻滞术后认知功能障碍发生率高。
Abstract:
-

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备注/Memo

备注/Memo:
基金项目:泉州市科技计划项目(2014Z73)
更新日期/Last Update: 2017-11-20