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[1]栾云,许华宁,吴意赟,等.超声造影对提高乳腺肿块系统分类准确性的价值评估[J].医学研究与战创伤救治(原医学研究生学报),2018,20(05):511-514.[doi:10.3969/j.issn.1672-271X.2018.05.014]
　LUAN Yun,XU Hua-ning,WU Yi-yun,et al.Evaluation the role of contrast-enhanced ultrasound in BI-RADS-US[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2018,20(05):511-514.[doi:10.3969/j.issn.1672-271X.2018.05.014]
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超声造影对提高乳腺肿块系统分类准确性的价值评估()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年05期
页码:
511-514
栏目:
临床研究
出版日期:
2018-09-18

文章信息/Info

Title:
Evaluation the role of contrast-enhanced ultrasound in BI-RADS-US
作者:
栾云; 许华宁; 吴意赟; 宋旭光
作者单位：210029南京，南京中医药大学附属医院/江苏省中医院超声医学科（栾云、许华宁、吴意赟、宋旭光）
Author(s):
LUAN Yun;  XU Hua-ning;  WU Yi-yun;  SONG Xu-guang
（Department of Ultrasound, Affiliated Hospital of Nanjing University of Traditional Chinese Medicine / Jiangsu Province Hospital of TCM, Nanjing 210029, Jiangsu, China）
关键词:
乳腺肿块; 超声造影; 微循环; 灌注; 鉴别诊断
Keywords:
breast masses; contrast-enhanced ultrasound; microcirculation; perfusion; differential diagnosis
分类号:
R737.9；R445.1
DOI:
10.3969/j.issn.1672-271X.2018.05.014
文献标志码:
A
摘要:
目的 基于美国放射学会乳腺超声报告与数据系统(BI-RADS-US)评分标准，采用联合超声造影对乳腺肿块进行分类，比较其与单纯常规超声分类的差异；并评价超声造影对乳腺良恶性肿块的鉴别诊断能力。方法 收集247例经病理证实的乳腺肿块，分别采用常规超声和联合超声造影对肿块进行BI-RADS-US分类，采用χ2检验评价两者间差异。参照病理结果 ，采用受试者工作特征曲线，比较两种方法 对乳腺良恶性肿块的鉴别诊断能力。结果 在常规超声基础上增加超声造影检查，对乳腺肿块的分类发生变化，表现为3类和5类病例数增多（3类增加40例、5类增加49例）、4类病例数减少（4a减少76例、4b减少7例、4c减少4例）；常规超声和联合超声造影对乳腺肿块的BI-RADS-US分类差异有统计学意义（P＜0.01）；联合超声造影对良恶性肿块的鉴别诊断能力优于常规超声（曲线下面积分别为0.908 vs 0.722, P＜0.01）。结论 在常规超声对乳腺肿块分类的基础上，联合超声造影技术，能提高对乳腺肿块分类的准确性，提高对良恶性肿块的鉴别诊断能力。
Abstract:
Objective Based on breast imaging reporting and data system for ultrasonography (BI-RADS-US), this study aims to compare the difference of classification for breast masses between ultrasound (US) and combined contrast-enhanced ultrasound (CEUS). To evaluate the efficiency of combined CEUS in differential diagnosis of benign and malignant masses.Methods Total 247 cases of breast masses were enrolled in this approved retrospective study. All masses were classified according to US and combined CEUS respectively, based on BI-RADS-US. Chi square test was used to analyze the difference of classification between US and combined CEUS. The diagnostic efficacy of combined CEUS in terms of sensitivity and specificity were analyzed by receiver operating characteristic (ROC) curve analyses.Results After combined with CEUS characteristics, the changes of BI-RADS-US classification were mainly manifested by an increase in class 3 and class 5 (40 cases in class 3, 49 cases in class 5) and a decrease in class 4 (76 cases in class 4a, 7 cases in class 4b, and 4 cases in class 4c).There was statistical difference in classification for breast masses between US and combined CEUS（P＜0.01）. The area under the curve (AUC) was 0.908 for combined CEUS and 0.722 for US（P＜0.01）.Conclusion On the basis of conventional US BI-RADS-US classification, the combination of CEUS is helpful to improve the evaluation ability of BI-RADS-US classification for breast masses.

参考文献/References:

[1]杜睿,薛玉,张歆, 等. Logistic回归分析在超声造影诊断乳腺浸润性导管癌中的应用价值[J].中国医学计算机成像杂志, 2013,19 (3):270-273.
[2]左文思, 冷晓玲, 马富成. 超声造影对乳腺BI-RADS4B级肿块的诊断价值[J]. 海南医学, 2016, 27 (2):231-235.
[3]杜睿, 薛玉. 超声造影及弹性成像技术在乳腺肿瘤诊断的现状与进展[J]. 医学研究生学报, 2013, 26 (4):435-437.
[4]朱巧英, 周锋盛, 陈俊, 等. 对比增强超声造影对乳腺不典型肿块的诊断价值[J]. 江苏医药, 2014, 40(13):1559-1561.
[5]朱巧英, 周锋盛, 周婉, 等. 灰阶超声造影对乳腺BI-RADS-US4类病灶的应用价值[J]. 中华超声影像学杂志, 2015, 24(10):890-893.
[6]Cao X, Xue J, Zhao B. Potential application value of contrast-enhanced ultrasound in neo-adjuvant chemotherapy of breast cancer [J].Ultrasound Med Biol, 2012, 38(12): 2065-2071.
[7]Ryschich E, Schmidt J, Hammerling OJ, et al. Transformation of the microvascular system during multistage tumorigenesis[J]. Int J Cancer, 2002, 97(6): 719-725.
[8]李颖嘉, 文戈, 杨莉. 超声造影及其定量分析对乳腺癌恶性转化过程中血管生成作用的评价[J]. 中华医学杂志, 2009, 89(9):587-591.
[9]曾锦树, 陈世良, 许翔, 等. 超声造影在乳腺良恶性病灶鉴别诊断中的应用[J]．中国超声医学杂志, 2013, 29(6):500-503.
[10]刘伟宗, 张家庭, 李泉水, 等. 乳腺超声BI-RADS分级诊断联合超声造影对乳腺肿块良恶性的诊断价值[J]．浙江临床医学, 2015, 17(8):1406-1407.
[11]马淑梅, 郑云慧, 才让卓玛，等. 乳腺良恶性肿块的超声造影参数成像特征研究[J]．中国超声医学杂志, 2014, 30(9):778-781.
[12]钱小霞, 司芩, 钱晓莉, 等. 乳腺癌超声造影特征分析[J]. 中华超声影像学杂志, 2012, 21(21): 217-219.
[13]Sorelli PG, Cosgrove DO, Svensson WE, et al. Can contrast-enhanced sonography distinguish benign from malignant breast masses?[J] J Clin Ultrasound, 2010, 38(4): 177-181.
[14]张晓颖, 戴瑞如, 成建萍. 超声造影联合弹性成像技术在乳腺疾病诊断上的应用价值[J]. 川北医学院学报, 2016, 31(2): 161-164.
[15]黄炎, 李俊来, 王知力, 等. 实时剪切波弹性成像定量评价乳腺良恶性病变[J]. 中国医学影像技术, 2011, 27(3): 561-564.
[16]智慧, 肖晓云, 杨海云, 等. 超声弹性成像比值法与评分法在乳腺肿物诊断中的比较[J]. 中华超声影像学杂志, 2010, 19(2): 142-144.
[17]刘彧, 童清平, 连娟, 等. 乳腺癌弹性超声特征与分子生物学指标的相关性研究[J]. 东南国防医药, 2015, 17(2): 116-118.
[18]胡彦, 徐超丽, 杨斌. 超声弹性成像定量参数对乳腺实性肿块的鉴别诊断分析[J]. 医学研究生学报, 2016, 29(8): 836-840.

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更新日期/Last Update: 2018-09-20