|本期目录/Table of Contents|

[1]罗娟,韩克,汤晓秋,等.不同术式治疗早孕期剖宫产术后子宫瘢痕妊娠各分型的效果分析[J].医学研究与战创伤救治(原医学研究生学报),2018,20(06):586-591.[doi:10.3969/j.issn.1672-271X.2018.06.006]
 LUO Juan,HAN Ke,TANG Xiao-qiu,et al.Compare to the difference of different surgical treatments in curing the early cesarean scars pregnancy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2018,20(06):586-591.[doi:10.3969/j.issn.1672-271X.2018.06.006]
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不同术式治疗早孕期剖宫产术后子宫瘢痕妊娠各分型的效果分析()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年06期
页码:
586-591
栏目:
临床研究
出版日期:
2018-11-20

文章信息/Info

Title:
Compare to the difference of different surgical treatments in curing the early cesarean scars pregnancy
作者:
罗娟韩克汤晓秋周怀君
作者单位:210008南京,南京大学医学院附属鼓楼医院妇产科(罗娟、韩克、汤晓秋、周怀君)
Author(s):
LUO Juan HAN Ke TANG Xiao-qiu ZHOU Huai-jun
(Department of Obstetrics and Gynecology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu,China)
关键词:
剖宫产术后子宫瘢痕妊娠瘢痕妊娠分型手术治疗
Keywords:
cesarean scars pregnancy classification surgical treatment
分类号:
R714.22
DOI:
10.3969/j.issn.1672-271X.2018.06.006
文献标志码:
A
摘要:
目的 探讨早孕期剖宫产术后子宫瘢痕妊娠(CSP)各临床分型的手术治疗效果。方法 选择2013年1月至2018年2月确诊为CSP的患者183例为观察对象,并将其分为Ⅰ型组55例、Ⅱ型组77例、Ⅲ型组26例、包块型组25例。对各分型中行腹腔镜或B超监视下清宫术、腹腔镜或B超监视下清宫术+水囊填塞术、腹腔镜下清除胚胎联合清宫术+子宫瘢痕切除修补术及子宫动脉介入栓塞术后清宫术4种手术方式的治疗效果进行分析,比较各手术治疗CSP的手术时间、术中出血量、住院时间、术后阴道流血时间、术后月经来潮时间以及术后血β-HCG降至正常时间。结果 腹腔镜或B超监视下清宫术、腹腔镜或B超监视下清宫术+水囊填塞治疗Ⅰ型、Ⅱ型、Ⅲ型及包块型CSP的术中出血量呈上升趋势;而腹腔镜下清除胚胎联合清宫术+子宫瘢痕切除修补术及子宫动脉介入栓塞术后清宫术治疗各型CSP的术中出血量无明显差异。上述4种手术方式在治疗Ⅰ型、Ⅱ型CSP的手术时间、住院时间、术后阴道流血时间、术后月经来潮时间以及术后血β-HCG降至正常时间比较差异无统计学意义(P>0.05);而腹腔镜下清除胚胎联合清宫术+子宫瘢痕切除修补术治疗Ⅲ型、包块型CSP患者,术后阴道流血时间、术后月经来潮时间、术后血β-HCG降至正常时间均短于上述其他3种手术方法 (P<0.05)。结论 孕早期CSP的手术治疗方案可根据临床分型选择合理的有效治疗措施,腹腔镜或B超监视下清宫术适用于Ⅰ型、Ⅱ型CSP患者;腹腔镜下清除胚胎联合清宫术+子宫瘢痕切除修补术更适用于Ⅲ型、包块型CSP患者。
Abstract:
Objective Cesarean scars pregnancy (CSP) may seriously threaten the reproductive health. In this essay, we investigated the difference of different surgical treatments in curing the early CSP.Methods One hundred and eighty-three patients diagnosed with CSP during January 2013 to February 2018 were analyzed, which divided into type Ⅰ group(55 cases), type Ⅱ group(77 cases), type Ⅲ group(26 cases), and mass type group(25 cases). We evaluated the effect of suction curettage under surveillance of laparoscopy or ultrasound, suction curettage under surveillance of laparoscopy or ultrasound + water pocket application, suction curettage after uterine artery embolization and combination of embryos clearing under laparoscopic and suction curettage + uterine scar resection and repair in all clinical types of CSP. The operation time, intraoperative blood loss, hospital stays, postoperative vaginal bleeding time, postoperative menstrual time and the returning normal time of blood β-HCG were analyzed to evaluate the outcomes of different surgical treatments.Results The amount of bleeding was on the rise during the operation among suction curettage under surveillance of laparoscopy or ultrasound, suction curettage under surveillance of laparoscopy or ultrasound + water pocket application curing type Ⅰ, type Ⅱ, type Ⅲ and mass type. The amount of bleeding among suction curettage after uterine artery embolization and combination of embryos clearing under laparoscopic and suction curettage + uterine scar resection and repair in all clinical types of CSP was shown nonsignificant difference. There was also no difference of the operation time, intraoperative blood loss, hospital stays, postoperative vaginal bleeding time, postoperative menstrual time and the returning normal time of blood β-HCG among the four kinds of surgical ways in the treatment of type Ⅰ or Ⅱ CSP (P>0.05). It was recommended to perform the combination of embryos clearing under laparoscopic and suction curettage + uterine scar resection and repair in curing type Ⅲ or mass cesarean scars pregnancy, including shortening the postoperative vaginal bleeding time, menstruation recovery time and the restoration time of blood β-HCG (P<0.05).Conclusion Appropriate ways should be chosen to treat early CSP based on the clinical classifications. According to our study, suction curettage under surveillance of laparoscopy or ultrasound can be used for type Ⅰ, type Ⅱ CSP. The combination of embryos clearing under laparoscopic and suction curettage + uterine scar resection and repair can be used for type Ⅲ and mass type.

参考文献/References:

[1]中华医学会妇产科学分会计划生育学组.剖宫产术后子宫瘢痕妊娠诊治专家共识(2016)[J].中华妇产科杂志,2016,51(8):568-569.
[2]Elson CJ,Salim R,Potdar N,et al.Diagnosis and management of ectopic pregnancy[J]. BJOG, 2016, 123(13):e15-e55.
[3]谢幸,苟文丽.妇产科学[M].8版.北京:人民卫生出版社,2013:58.
[4]Vial Y,Petignat P,Hohlfeld P.Pregnancy in a cesarean scar [J].Ultrasound Obstet Gynecol, 2000, 16(7):592-593.
[5]Cheng LY,Wang CB,Chu LC,et al.Outcomes of primary surgical evacuation during the first trimester in different types of implantation in women with cesarean scar pregnancy[J]. Fert Steril,2014,102(5):1085-1090.
[6]Peng P,Gui T,Liu X,et al.Comparative efficacy and safety of local and systemic methotrexate injection in cesarean scar pregnancy[J].Ther Clin Risk Manag, 2015,11:137-142.
[7]Timor-Tritsch IE,Monteagudo A,Cali G,et al.Cesarean scar pregnancy and early placenta accreta share common histology[J].Ultrasound Obstet Gynecol,2014,43(5):383-395.
[8]Hellerstein S,Feldman S,Duan T. Survey of obstetric care and cesarean delivery rates in Shanghai, China[J].Birth,2016,43(4):193-199.
[9]Xiong X,Yan P,Gao C,et al.The value of contrast-enhanced ultrasound in the diagnosis of cesarean scar pregnancy[J]. Biomed Res Int, 2016:4762785. doi:10.1155/2016/4762785.
[10]刘真真,戴晴,王铭,等. 包块型剖宫产瘢痕妊娠临床及超声特征分析[J].中国医学影像技术, 2013, 29(7):1006-1010.
[11]杨斌,肖梅,陈赛英,等.子宫瘢痕妊娠的影像学特征及临床治疗[J].东南国防医药,2017,19(6):595-599.
[12]Li C,Li C,Feng D,et al. Transcatheter arterial chemoembolization versus systemic methotrexate for the management of cesarean scar pregnancy[J].Int J Gynaecol Obstet,2011,113(4):178-182.
[13]Nawroth F, Foth D, Wilhelm L,et al. Conservative treatment of ectopic in a cesarean section scar with methotrexate: a case report[J]. Eur J Obstet Gynecol Reprod Biol,2001,99(2):135-137.
[14]Huang L,Li Y,Chen Z,et al.An application of uterine artery chemoembolization in treating cesarean scar pregnancy[J].Int J Clin Exp Med,2015,8(2):2570-2577.
[15]Lan W,Hu D,Li Z,et al.Bilateral uterine artery chemoembolization combined with dilation and curettage for treatment of cesarean scar pregnancy: A method for preserving the uterus[J].J Obstet Gynaecol Res,2013,39(6):1153-1158.
[16]Berkane N,Moutafoff-Borie C.Impact of previous ut-eri-neartery embolization on fertility [J].Curr Opin Obstet Gynecol, 2010,22(4):242-247.
[17]Arthur R,Kachura J,Liu G, et al.Laparoscopic myomectomy versus uterine artery embolization: long-term impact on markers of ovarian reserve[J].J Obstet Gynaecol Can,2014,36(3):240-247.

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更新日期/Last Update: 2018-11-20