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[1]张婷,薛飞,程友.持续性变应性鼻炎药物治疗时间与疗效相关性调查[J].医学研究与战创伤救治(原医学研究生学报),2019,21(01):30-32.[doi:10.3969/j.issn.1672-271X.2019.01.007]
　ZHANG Ting,XUE Fei,CHENG You.Investigation oncorrelation between time and effect of drug therapy for persistent allergic rhinitis[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2019,21(01):30-32.[doi:10.3969/j.issn.1672-271X.2019.01.007]
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持续性变应性鼻炎药物治疗时间与疗效相关性调查()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第21卷
期数:
2019年01期
页码:
30-32
栏目:
临床研究
出版日期:
2019-01-20

文章信息/Info

Title:
Investigation oncorrelation between time and effect of drug therapy for persistent allergic rhinitis
作者:
张婷; 薛飞; 程友
作者单位：210002南京，东部战区总医院耳鼻咽喉-头颈外科（张婷、薛飞、程友）
Author(s):
ZHANG Ting;  XUE Fei;  CHENG You
(Department of Otolaryngology-Head and Neck Surgery,General Hospital of Eastern Theater Command,Nanjing 210002,Jiangsu, China)
关键词:
持续性变应性鼻炎; 治疗时间; 停药; 复发
Keywords:
persistent allergic rhinitis;  treatment time;  drug withdrawal;  relapse
分类号:
R765.21
DOI:
10.3969/j.issn.1672-271X.2019.01.007
文献标志码:
A
摘要:
目的 分析变应性鼻炎患者药物治疗时间长短与疗效的相关性。方法 成功完成97例变应性鼻炎患者电话调查，根据是否合并哮喘分为单纯变应性鼻炎组（61例）和变应性鼻炎伴哮喘组（36例），详细了解其症状及用药现状，建立相应的个人数据库档案，并进行数据统计学分析。结果 变应性鼻炎组在1个月内复发的患者，其平均治疗时间为（4.75±2.77）周，明显短于其他患者（P＜0.05），而停药后在1～3月、3～6个月、6～9个月及9～12个月内复发患者，其治疗时间之间比较差异无统计学意义（P＞0.05）。变应性鼻炎伴哮喘组在1个月内复发的患者，其平均治疗时间为（5.17±2.79）周，也明显短于其他患者（P＜0.05）；而停药后在1～3个月、3～6个月及6～9个月内复发患者，其治疗时间之间比较差异无统计学意义（P＞0.05）。结论 持续变应性鼻炎患者停药后非常容易复发，提示持续性变应性鼻炎患者用药需逐渐减量至“最低维持治疗量”并长期使用。
Abstract:
Objective To analyze the correlation between time and effect of drug therapy in patients with allergic rhinitis.Methods The questionnaire survey of 97 allergic rhinitis patients areas were carried out. The patients were divided into allergic rhinitis group and allergic rhinitis with asthma group according to whether they were combined with asthma. Their clinical situations were investigated in detail and the database was created for statistics.Results Of the Investigation, the average treatment time of patients in allergic rhinitis group who relapse within 1 month were (4.75±2.77) weeks, which were significantly shorter than other patients and the data had significant differences(P<0.05). Patients who relapse within 1-3 months, 3-6 months, 6-9 months and 9-12 months,which treatment time had no significant differences(P>0.05). The average treatment time of patients in allergic rhinitis with asthma group who relapse within 1 month was (5.17±2.79) weeks, which was significantly shorter than other patients and the data had significant differences(P<0.05). Patients who relapse within 1-3 months, 3-6 months, 6-9 months and 9-12months,which treatment time had no significant differences(P>0.05).Conclusion Patients with persistent allergic rhinitis are easy to relapse after drug withdrawal, which showed that drug for patients with persistent allergic rhinitis need reduce the “Minimum maintenance treatment” and maintain for a long time.

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备注/Memo

备注/Memo:
基金项目：中国博士后科学基金（2017M613438）
更新日期/Last Update: 2019-01-20