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[1]李增,肖杰,龙浩,等.基于MRI分析黄韧带横截面积与神经根沉降征的相关性[J].医学研究与战创伤救治(原医学研究生学报),2019,21(5):478-481.[doi:10.3969/j.issn.1672-271X.2019.05.007]
　LI Zeng,XIAO Jie,LONG Hao,et al.Correlation between ligamentum flavum area and nerve root sedimentation sign based on MRI analysis[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2019,21(5):478-481.[doi:10.3969/j.issn.1672-271X.2019.05.007]
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基于MRI分析黄韧带横截面积与神经根沉降征的相关性()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第21卷
期数:
2019年5期
页码:
478-481
栏目:
临床研究
出版日期:
2019-09-06

文章信息/Info

Title:
Correlation between ligamentum flavum area and nerve root sedimentation sign based on MRI analysis
文章编号:
1672-271X（2019）05-0478-04
作者:
李增; 肖杰; 龙浩; 古娟
作者单位：550002 贵阳，贵阳中医学院研究生院（李增、古娟）；550002 贵阳，贵阳市第四人民医院脊柱外科（肖杰、龙浩）
Author(s):
LI Zeng1;  XIAO Jie2;  LONG Hao2;  GU Juan1
(Graduate School of Guiyang College of Traditional Chinese Medicine, Guiyang 550002, Guizhou, China)
关键词:
中央型腰椎管狭窄症;  神经根沉降征;  黄韧带面积;  硬膜囊横截面积;  有效矢状径
Keywords:
Lumbar central spinal stenosis;  nerve root sedimentation sign;  ligamentum flavum area;  cross-sectionalarea;  effective sagittal diameter
分类号:
R681.5
DOI:
10.3969/j.issn.1672-271X.2019.05.007
文献标志码:
A
摘要:
目的 分析黄韧带面积（LFA）与中央型腰椎管狭窄症中神经根沉降征（NRS）的相关性。 方法 回顾性分析2016年9月至2018年6月贵阳市第四人医院脊柱外科收治并且明确诊断为中央型腰椎管狭窄症患者90例的临床资料，MRI明确为单节段（L4/5）狭窄，至少一个扫描层面的硬膜囊横截面积(CSA)≤100 mm2。根据NRS分为阳性组和阴性组。通过surgimap测量L4/5节段LFA、CSA和最小椎管有效矢状径(ESD)。采用受试者工作特征曲线(ROC-curve)分析LFA和NRS相关性。 结果 NRS阳性患者47例，阴性患者43例。NRS阳性组LFA为（140.69±8.79）mm2，NRS阴性组LFA为（119.30±11.94）mm2。2组的年龄、LFA、CSA、ESD差异均具有统计学意义（P<0.01）。ROC曲线分析显示LFA作为NRS阳性的预测因子的最佳临界点为130.63 mm2，敏感性为93.6％，特异性为86.0％，AUC为0.940（95％CI：0.890～0.989，P<0.01）。 结论 NRS阳性的发生与LFA有关，LFA可作为评估腰椎管狭窄节段硬膜囊变窄程度的一个定量指标。
Abstract:
Objective To analysis the correlation between the ligamentum flavum area (LFA) and the nerve root sedimentation sign (NRS) in lumbar central spinal stenosis （LCSS）. Methods The clinical data of 90 patients with LCSS who were admitted to orthopedics in the Guiyang Fourth People Hospital from September 2016 to June 2018 were retrospectively analyzed. The single segment stenosis (L4/5) was clearly diagnosed on MRI. At least one scan layer of the dural sac cross-sectional area (CSA) ≤100 mm2.The patients were divided into positive group and negative group according to NRS. LFA,CSA,and effective sagittal diameter (ESD) of L4/5 segmental were measured by surgimap. The correlation between LFA and NRS by Receiver Operating Characteristic Curve (ROC-curve). Results There were 47 cases of NRS positive and 43 cases of NRS negative. The average LFA of the NRS positive group was （140.69±8.79）mm2, and the average LFA of the NRS negative group was （119.30±11.94）mm2. The age, CSA, ESD and LFA of NRS positive group and NRS negative group were statistically significant (P<0.01). ROC-curve analysis showed that the best cut-off point for the LFA was 130.63 mm2, with 93.6％ sensitivity,86.0％ specificity, and area under the curve (AUC) of 0.940（95％CI：0.890-0.989，P<0.01）. Conclusion The occurrence of NRS positive is related to LFA. LFA can be used as a quantitative indicator to assess the degree of narrowing of the dural sac in lumbar spinal stenosis.

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备注/Memo

备注/Memo:
收稿日期：2018-11-05
更新日期/Last Update: 2019-09-06