[1]雷月,朱烨,李娟,等.MRI联合鳞状细胞癌抗原在宫颈鳞状细胞癌淋巴结转移的诊断价值[J].医学研究与战创伤救治(原医学研究生学报),2019,21(5):524-526.[doi:10.3969/j.issn.1672-271X.2019.05.017]
点击复制
MRI联合鳞状细胞癌抗原在宫颈鳞状细胞癌淋巴结转移的诊断价值(
)
)《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]
- 卷:
- 第21卷
- 期数:
- 2019年5期
- 页码:
- 524-526
- 栏目:
- 出版日期:
- 2019-09-06
文章信息/Info
- Title:
- -
- 文章编号:
- 1672-271X（2019）05-0524-03
- Keywords:
- -
- 分类号:
- R711.74
- 文献标志码:
- B
- 摘要:
- 目的 探讨MRI联合鳞状细胞癌抗原(SCC-Ag)在宫颈鳞状细胞癌淋巴结转移的诊断价值。 方法 回顾性分析南京医科大学附属南京妇产医院2017年1月至2019年2月收治的宫颈鳞状细胞癌患者163例的临床资料，与病理学诊断对照，评价MRI、SCC-Ag及两者联合诊断淋巴结转移的临床价值。 结果 163例患者中MRI提示31例发生淋巴结转移，与术后病理证实的37例相比，单独使用MRI评估盆腔淋巴结转移的敏感度为64.86%，特异度为94.44%，血清SCC-Ag预测淋巴结转移的最佳临界值为4.55 ng/mL，MRI与SCC-Ag联合诊断盆腔淋巴结转移的敏感度为86.49%，特异度为88.89%。 结论 单独使用MRI对无淋巴结转移的患者具有一定的预测价值，但诊断盆腔淋巴结转移敏感度不高，SCC-Ag可辅助MRI联合诊断提高盆腔淋巴结阳性患者的检出率。
- Abstract:
- -
参考文献/References:
1 石彩歌, 顾芸, 耿建祥, 等. 宫颈鳞癌及腺癌组织HPV感染型别分布的对比研究[J]. 医学研究生学报, 2018, 31(8):840-843.
2 TorreLA, BrayF, SiegelRL, et al. Global cancer statisctics[J]. CA Cancer J Clin, 2015, 65(2):100.
3 NeerjaB, DaisukeA, DayaNS, et al. Cancer of the cervix uteri[J]. Int J Gynecol Obstet, 2018, 143(Suppl2): 22-36.
4 TsunodaAT, MarinitzS, SoaresNJ, et al.Incidence of histologically proven pelvic and para-alrtic lymph node metastases and rate of upstaging in patients with locally advanced cervical cancer: results of a prospective randomized trial[J]. Oncology, 2017, 92(4): 213-220.
5 夏程程, 石红.宫颈癌淋巴结转移及宫旁浸润诊断研究进展[J]. 中国实用妇科与产科杂志, 2017, 33(5): 534-538.
6 王微, 齐军.血清鳞状细胞癌抗原对宫颈鳞癌淋巴结转移的预测价值[J]. 标记免疫分析与临床, 2018, 25(1): 1-4.
7 WangW, JiaHL, HuangJM, et al. Indentification of biomarkers for lymph node metastasis in early-stage cervical cancer by tissue-based proteomics[J]. Br J Cancer, 2014, 110(7): 1748-1758.
8 AlcazarJL, ArribasS, MinguezJA, et al. The role of ultrasound of uterine cervical[J]. Obstet Gynaecol India, 2014, 64(5):311-316.
9 TestaAC, Prof, LeggeAD, et al.Imaging techniques for the evaluaiton of cervical cancer[J]. Best Pract Res Clin Obstet Gynaecol, 2014, 28(5): 741-758.
10 SalvaticiM, AchilarreM, SandriMT, et al.Squamous cell carc inoma antigen(SCC-Ag) during follow-up of cervical cancer patients:Role in the early diagnosis ofrecurrence[J]. Gynecologic Oncology, 2016, 142(1): 115.
11 JeongBK, ChoiDH, HuhSJ, et al.The role of squamous cell carcinoma antigen as a prognostic and predictive factoer in carcinoma of uterine cervix[J]. Radiat Oncol, 2011, 29(3): 191-198.
12 冯淑瑜, 张彦娜, 刘建刚. 宫颈癌淋巴结转移的高危因素及预后分析[J]. 癌症, 2005, 24(10): 1261-1266.
13 李英, 刘坤, 杨瀚. 血清SCC-Ag、CK19水平变化与宫颈癌患者淋巴结转移的关联性分析[J]. 实验与检验医学, 2018, 36(6): 950-952.
14 GadducciA, TanaR, CosioS, et al. The serum assay of tumour makers in prognostic evaluation, treatment monitoring and follow-up of patients with cervical cancer:a review of the literature[J]. Crit Rev Oncol Hematol, 2008, 66(1): 10-20.
15 LiX, ZhouJ, HuangK, et al. The predictive value of serum squamous cell carcinoma antigen in patients with cervical cancer who receive neoadjuvant chemotherapy followed by radical surgery: a single-institute study[J]. PLoS One, 2015, 10(4): 1-12.
相似文献/References:
[1]江 源,翁 侨,韩 克,等.MRI对于子宫内膜癌腹膜后淋巴结转移的诊断价值[J].医学研究与战创伤救治(原医学研究生学报),2013,15(04):399.[doi:10.3969/j.issn.1672-271X.2013.04.027]
[2]吴 曼,骆文香,崔向华,等.结肠癌宫颈转移1例[J].医学研究与战创伤救治(原医学研究生学报),2012,14(01):26.
[3]陶一蕾,邱玲琍,王 冰.早期巨块型宫颈癌术前放化疗的临床研究[J].医学研究与战创伤救治(原医学研究生学报),2010,12(04):344.
[4]朱皓皞,于晓红,杜丽英,等.宫颈癌中激活蛋白1通路的活化及临床意义[J].医学研究与战创伤救治(原医学研究生学报),2014,16(02):128.[doi:10.3969/j.issn.1672-271X.2014.02.005]
ZHU Hao-hao,YU Xiao-hong,DU Li-ying,et al.Clinical significance of AP-1 pathway alterations in cervical carcinoma[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2014,16(5):128.[doi:10.3969/j.issn.1672-271X.2014.02.005]
[5]张 飞,朱湘玉,杨瑞宁.液基涂片细胞学检查联合高危型HPV检测在宫颈病变诊断中的价值[J].医学研究与战创伤救治(原医学研究生学报),2016,18(01):28.[doi:10.3969/j.issn.1672-271X.2016.01.008]
ZHANG Fei,ZHU Xiang-yu,YANG Rui-ning..The value of diagnosing cervical lesions by Thinprep cytologic test (TCT) combined with high-risk type HPV DNA testing[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(5):28.[doi:10.3969/j.issn.1672-271X.2016.01.008]
[6]丁 虹,唐雯静,庞燕芬,等.马齿苋多糖对宫颈癌细胞恶性生物学行为抑制作用的实验研究[J].医学研究与战创伤救治(原医学研究生学报),2016,18(01):38.[doi:10.3969/j.issn.1672-271X.2016.01.011]
DING Hong,TANG Wen-jing,PANG Yan-fen,et al.Animal study on the inhibition effect of Portulaca oleracea polysaccharide on malignant behavior of cervical cancer cells[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(5):38.[doi:10.3969/j.issn.1672-271X.2016.01.011]
[7]范佳杨,梁婷,刘康,等.糖酵解关键酶在宫颈癌Warburg效应中的作用研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(02):175.[doi:10.3969/j.issn.1672-271X.2021.02.014]
FAN Jia-yang,LIANG Ting,LIU Kang,et al.Research progression of the infection of glycolytic enzymein the Warburg effect in cervical cancer[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(5):175.[doi:10.3969/j.issn.1672-271X.2021.02.014]
[8]胡丽花,赵嫦娥,宋成文.增敏化疗对宫颈癌同步放疗患者生存质量和免疫功能的影响研究[J].医学研究与战创伤救治(原医学研究生学报),2021,23(6):588.[doi:10.3969/j.issn.1672-271X.2021.06.006]
HU Li-hua,ZHAO Chang-e,SONG Cheng-wen.Study on the effect of sensitization chemotherapy on the quality of life and immune function of patients with cervical cancer receiving concurrent radiotherapy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(5):588.[doi:10.3969/j.issn.1672-271X.2021.06.006]
[9]王霁,唐媛媛,华羽晨,等.便携式膀胱扫描仪在宫颈癌患者CT模拟定位及调强放疗中的精准应用[J].医学研究与战创伤救治(原医学研究生学报),2022,24(1):83.[doi:10.3969/j.issn.1672-271X.2022.01.019]
备注/Memo
- 备注/Memo:
- 收稿日期：2019-04-01
常用功能
统计/Statistics
- 摘要浏览/Viewed688
- 全文下载/Downloads336
- 评论/Comments
