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[1]陈月凤,陈达丰,钟伟,等.保乳联合前哨淋巴结活检治疗早期乳腺癌[J].医学研究与战创伤救治(原医学研究生学报),2020,22(6):617-621.[doi:10.3969/j.issn.1672-271X.2020.06.013]
　CHEN Yue-feng,CHEN Da-feng,ZHONG Wei,et al.Treatment of early breast cancer with breast-conserving surgery combined with sentinel-lymph-node biopsy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2020,22(6):617-621.[doi:10.3969/j.issn.1672-271X.2020.06.013]
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保乳联合前哨淋巴结活检治疗早期乳腺癌()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第22卷
期数:
2020年6期
页码:
617-621
栏目:
临床研究
出版日期:
2020-11-20

文章信息/Info

Title:
Treatment of early breast cancer with breast-conserving surgery combined with sentinel-lymph-node biopsy
作者:
陈月凤; 陈达丰; 钟伟; 陈华福; 周松
作者单位：363000漳州，厦门大学附属东南医院（解放军联勤保障部队第九○九医院）普通外科（陈月凤、陈达丰、钟伟、陈华福、周松）
Author(s):
CHEN Yue-feng;  CHEN Da-feng;  ZHONG Wei;  CHEN Hua-fu;  ZHOU Song
（Department of General Surgery，Southeast Hospital Affiliated to Xiamen University/the 909th Hospital of the Joint Logistics Support Force，PLA, Zhangzhou 363000, Fujian, China）
关键词:
保乳手术; 前哨淋巴结活检; 乳腺癌改良根治术; 效果观察
Keywords:
breast-conserving surgery;  sentinel-lymph-node biopsy;  modified radical mastectomy;  effect observation
分类号:
R737.9
DOI:
10.3969/j.issn.1672-271X.2020.06.013
文献标志码:
A
摘要:
目的比较保乳联合前哨淋巴结活检术与改良根治术治疗乳腺癌的围手术期及临床相关指标的优劣。方法回顾性分析2013年1月至2019年6月厦门大学附属东南医院术前活检病理确诊的乳腺癌患者临床资料，保乳联合前哨淋巴结活检术50例早期乳腺癌患者为保乳组，同期行乳腺癌改良根治术50例患者为改良根治组。统计2组患者围手术期指标包括手术时间、术中出血量、腋下术后总引流量、腋下引流管拔管时间，随访调查术后半年患侧乳房的美容效果及患侧肩关节功能情况。结果保乳组在手术时间[（155.91±25.96）min]、腋下引流管拔管时间[（5.86±8.18）d]明显短于改良根治组[（167.12±18.51）min、（12.01±10.82）d,P＜0.05]，术中出血量[(46.92±13.66)mL]、术后腋下引流量[(107.69±6.48)mL]均少于改良根治组[(68.87±9.81)mL、(391.27±9.48)mL,P＜0.01]。保乳组患侧乳房均保持较好的乳房外形，优良率达94%。保乳组术后患侧肩关节功能评分较高(P<0.01)。结论保乳联合前哨淋巴结活检手术在围手术期指标、术后患侧乳房的美容效果、肩关节功能等方面均优于乳腺癌改良根治术，符合保乳条件的患者应争取保乳手术。
Abstract:
ObjectiveComparison of the perioperative and clinical indexes between breast conserving combined with sentinel lymph node biopsy and modified radical mastectomy for breast cancer.MethodsA retrospective analysis of 50 breast cancer patients treated with breast-conserving surgery combined with sentinel lymph node biopsy that were made up of the breast-conserving group, and another 50 patients with modified radical mastectomy were selected as the modified radical mastectomy group. By following up two groups of patients, the indexes of perioperative period including operation time, intraoperative blood loss, total drainage volume after axillary operation, and extubation time of subaxillary drainage tube, the beauty effect of the affected breast and the function of shoulder joint were investigated after half a year.ResultsThe operation time [(155.91±25.96) min] and axillary drainage tube extubation time [(5.86±8.18) d] in the breast-conserving group were significantly shorter than those in the modified radical mastectomy group [(167.12±18.51) min, (12.01±10.82) d, P<0.05], the amount of bleeding during operation [(46.92±13.66) mL] and the amount of axillary drainage after operation [(107.69±6.48) mL] were less than those the modified radical mastectomy group [(68.87±9.81) mL, (391.27±9.48) mL, P<0.01]. The affected breast in the breast-conserving group maintained the better breast shape with 94% excellence rate and higher shoulder function score (P<0.01).ConclusionBreast-conserving surgery combined with sentinel lymph node biopsy is better than the control group in the perioperative period, beauty effect of affected breast and shoulder function. It is strongly recommended that patients who meet the requirements of breast preservation surgery should undertake a breast-conserving surgery.

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相似文献/References:

[1]凡庆东,张在鸿,杨日高,等.蓝染料示踪早期乳腺癌前哨淋巴结活检52例临床分析[J].医学研究与战创伤救治(原医学研究生学报),2013,15(03):288.[doi:10.3969/j.issn.1672-271X.2013.03.026]

备注/Memo

备注/Memo:
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更新日期/Last Update: 2020-12-01