[1]沈书凝,徐步捷,郝雷雨,等.PCP信号通路关键因子VANGL在肿瘤细胞迁移和增殖中的作用研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(02):164-168.[doi:10.3969/j.issn.1672-271X.2021.02.012]
　SHEN Shu-ning,XU Bu-jie,HAO Lei-yu,et al.The role of VANGL, a key protein of the planar cell polarity signaling, in the migration and proliferation of cancer cells[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(02):164-168.[doi:10.3969/j.issn.1672-271X.2021.02.012]

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PCP信号通路关键因子VANGL在肿瘤细胞迁移和增殖中的作用研究进展()

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参考文献/References:

[1]Wolff T, Rubin GM. Strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila[J]. Devel Mar,125(6):1149-1159.
[2]Taylor J, Abramova N, Charlton J, et al. Van Gogh: a new Drosophila tissue polarity gene[J]. Genetics,1998,150(1):199-210.
[3]Jessen JR, Solnica-Krezel L. Identification and developmental expression pattern of van gogh-like 1, a second zebrafish strabismus homologue[J]. Gene Expr Patterns, 2004,4(3):339-344.
[4]Torban E, Kor C, Gros P. Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebrates[J].Trends Genet, 2004,20(11):570-577.
[5]Belotti E, Puvirajesinghe TM, Audebert S, et al. Molecular characterisation of endogenous VANGL2/VANGL1 heteromeric protein complexes[J].PLoS One, 2012,7(9):e46213.
[6]Iliescu A, Gravel M, Horth C, et al. Transmembrane topology of mammalian planar cell polarity protein VANGL1[J]. Biochemistry,2011, 50(12):2274-82.
[7]Mentink RA, Rella L, Radaszkiewicz TW, et al. The planar cell polarity protein VANG-1/VANGL negatively regulates WNT/beta-catenin signaling through a DVL dependent mechanism[J]. PLoS Genet, 2018,14(12):e1007840.
[8]Courbard JR, Djiane A, Wu J, et al. The apical/basal-polarity determinant Scribble cooperates with the PCP core factor Stbm/VANG and functions as one of its effectors[J]. Dev Biol, 2009,333(1):67-77.
[9]Iliescu A, Gros P. The intracellular carboxyl terminal domain of VANGL proteins contains plasma membrane targeting signals[J].Protein Sci, 2014,23(4):337-343.
[10]Merte J, Jensen D, Wright K, et al. Sec24b selectively sorts VANGL2 to regulate planar cell polarity during neural tube closure[J]. Nat Cell Biol, 2010,12(1):41-46.
[11]Guo Y, Zanetti G, Schekman R. A novel GTP-binding protein-adaptor protein complex responsible for export of VANGL2 from the trans Golgi network[J]. Elife, 2013,2:e00160.
[12]Treat AC, Wheeler DS, Stolz DB, et al. The PDZ Protein Na+/H+ Exchanger Regulatory Factor-1 (NHERF1) Regulates Planar Cell Polarity and Motile Cilia Organization[J].PLoS One, 2016,11(4):e0153144.
[13]Jessen TN, Jessen JR. VANGL2 protein stability is regulated by integrin alphav and the extracellular matrix[J].Exp Cell Res, 2019,374(1):128-139.
[14]Devenport D. The cell biology of planar cell polarity[J]. J Cell Biol, 2014,207(2):171-179.
[15]Humphries AC, Mlodzik M. From instruction to output: WNT/PCP signaling in development and cancer[J].Curr Opin Cell Biol, 2018,51:110-116.
[16]Luga V, Zhang L, Viloria-Petit AM, et al. Exosomes mediate stromal mobilization of autocrine WNT-PCP signaling in breast cancer cell migration[J]. Cell, 2012,151(7):1542-1556.
[17]Matis M, Russler-Germain DA, Hu Q, et al. Microtubules provide directional information for core PCP function[J]. Elife, 2014,3:e02893.
[18]Kibar Z, Torban E, McDearmid JR, et al. Mutations in VANGL1 associated with neural-tube defects[J]. N Engl J Med, 2007,356(14):1432-1437.
[19]Lei YP, Zhang T, Li H, et al. VANGL2 mutations in human cranial neural-tube defects[J]. N Engl J Med, 2010，362(23):2232-2235.
[20]Lee JH, Park SR, Chay KO, et al. KAI1 COOH-terminal interacting tetraspanin (KITENIN), a member of the tetraspanin family, interacts with KAI1, a tumor metastasis suppressor, and enhances metastasis of cancer[J]. Cancer Res, 2004,64(12):4235-4243.
[21]Lee JK, Bae JA, Sun EG, et al. KITENIN increases invasion and migration of mouse squamous cancer cells and promotes pulmonary metastasis in a mouse squamous tumor model[J]. FEBS Lett, 2009,583(4):711-717.
[22]Bui KC, Barat S, Chen X, et al. Silencing of Kangai 1 C-terminal interacting tetraspanin suppresses progression of cholangiocarcinoma[J]. Exp Cell Res, 2018,364(1):59-67.
[23]Lee KH, Ahn EJ, Oh SJ, et al. KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers[J]. Oncotarget, 2015,6(5):3240-3253.
[24]Oh HH, Park KJ, Kim N, et al. Impact of KITENIN on tumor angiogenesis and lymphangiogenesis in colorectal cancer[J]. Oncol Rep, 2016,35(1):253-260.
[25]Puvirajesinghe TM, Bertucci F, Jain A, et al. Identification of p62/SQSTM1 as a component of non-canonical WNT VANGL2-JNK signalling in breast cancer[J]. Nat Commun, 2016,7:10318.
[26]Hatakeyama J, Wald JH, Printsev I, et al. VANGL1 and VANGL2: planar cell polarity components with a developing role in cancer[J]. Endocr Relat Cancer, 2014,21(5):345-356.
[27]Anastas JN, Biechele TL, Robitaille M, et al. A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression[J]. Oncogene, 2012,31(32):3696-3708.
[28]Cha SW, Tadjuidje E, Wylie C, et al. The roles of maternal VANGL2 and aPKC in Xenopus oocyte and embryo patterning[J]. Development, 2011,138(18):3989-4000.
[29]Hayes MN, McCarthy K, Jin A, et al. VANGL2/RHOA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma[J]. Cell Stem Cell, 2018,22(3):414-427.
[30]Piazzi G, Selgrad M, Garcia M, et al. Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancers[J]. Br J Cancer, 2013,108(8):1750-1756.
[31]Wald JH, Hatakeyama J, Printsev I, et al. Suppression of planar cell polarity signaling and migration in glioblastoma by NRDP1-mediated DVL polyubiquitination[J]. Oncogene, 2017,36(36):5158-5167.

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