|本期目录/Table of Contents|

[1]吴正奇,张志镒,范志宁,等.胃经口内镜下肌切开术干预近端胃切除术后胃食管反流病临床疗效分析[J].医学研究与战创伤救治(原医学研究生学报),2021,23(03):253-256.[doi:10.3969/j.issn.1672-271X.2021.03.007]
　WU Zheng-qi,ZHANG Zhi-yi,FAN Zhi-ning,et al.Clinical analysis of G-POEM intervention for gastroesophageal reflux disease after proximal gastrectomy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(03):253-256.[doi:10.3969/j.issn.1672-271X.2021.03.007]
点击复制

胃经口内镜下肌切开术干预近端胃切除术后胃食管反流病临床疗效分析()
分享到62.8K

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年03期
页码:
253-256
栏目:
临床研究
出版日期:
2021-06-20

文章信息/Info

Title:
Clinical analysis of G-POEM intervention for gastroesophageal reflux disease after proximal gastrectomy
作者:
吴正奇; 张志镒; 范志宁; 卢林芝; 李世华; 赵光源; 张文鸿; 秦天燕
作者单位：733000武威,甘肃省武威肿瘤医院消化科（吴正奇、张志镒、卢林芝、李世华、赵光源、张文鸿、秦天燕）; 210029南京，江苏省人民医院内镜中心（范志宁）
Author(s):
WU Zheng-qi;  ZHANG Zhi-yi;  FAN Zhi-ning ; LU Lin-zhi;  LI Shi-hua;  ZHAO Guan-yuan;  ZHANG Wen-hong;  QIN Tian-yan
(1.Department of Digestive, Wuwei Cancer Hospital, Wuwei 733000, Gansu, China；2.Endoscopy Center, Jiangsu Provincial People’s Hospital, Nanjing 210029, Jiangsu, China)
关键词:
胃经口内镜下肌切开术; 近端胃切除术; 胃瘫; 胃食管反流病; Gerd Q量表
Keywords:
gastric per-oral endoscopic myotomy;  proximal gastrectomy;  gastroplegia; gastroesophageal reflux disease;  Gerd Q scale
分类号:
R655.4
DOI:
10.3969/j.issn.1672-271X.2021.03.007
文献标志码:
A
摘要:
目的通过对胃经口内镜下肌切开术（G-POEM）术程的详细描述和分析研究，探讨G-POEM干预近端胃切除术后胃食管反流病的疗效和价值。方法回顾性分析2018年5月-2019年12月在甘肃省武威肿瘤医院接受G-POEM手术治疗的25例近端胃切除术后胃食管反流患者的临床资料，收集术前及术后临床症状、Gerd Q量表评分、手术并发症、术后短期临床效果等数据资料，评估手术治疗后的疗效及安全性。结果25例患者均顺利完成G-POEM手术治疗，术后随访，患者病情均显著改善，反流症状控制良好，术前与术后不同时间段的Gerd Q量表评分差异有统计学意义（F=72.201，P<0.05），Gerd Q评分及胃镜检查提示治疗有效，患者在术后1年内无并发症出现。结论G-POEM是一种安全可行、创伤小且有效的治疗近端胃切除术后引起的胃食管反流病的手术，在未来更多的临床研究中有望进一步评估该手术的安全性和疗效等。
Abstract:
ObjectiveTo discuss the efficacy and clinical value of G-poem in patients with postoperative gastroesophageal reflux disease after proximal gastrectomy through a detailed description and analysis of the procedure of gastric per-oral endoscopic myotomy (G-POEM).MethodsThe clinical data of 25 patients with gastroesophageal reflux after proximal gastrectomy who underwent G-POEM surgery at Wuwei Cancer Hospital in Gansu Province from May 2018 to December 2019 were retrospectively analyzed, and their preoperative and postoperative data were collected. Clinical symptoms, Gerd Q score, surgical complications, short-term postoperative clinical results and other data are used to evaluate the efficacy and safety of surgical treatment.ResultsAll 25 patients successfully completed the G-POEM surgical treatment. Follow-up after the operation showed that the patient’s condition was significantly improved, and the reflux symptoms were well controlled. There was a statistically significant difference in the Gerd Q scale scores between preoperative and postoperative periods (F=72.201, P<0.05), Gerd Q score and gastroscopy showed that the treatment was effective, and the patient had no complications within a year after surgery.ConclusionG-poem is a feasible and effective method for postoperative gastroesophageal reflux disease after proximal gastrectomy. It is anticipated that the safety and efficacy of this operation will be further evaluated in more clinical studies in the future.

参考文献/References:

[1]所剑,李伟.近端胃切除术后胃食管反流防治[J].中国实用外科杂志,2017,37(4):351-355.
[2]刘林波,胥润,龚土平，等.管状胃吻合预防近端胃切除术后反流性食管炎的临床研究[J].西部医学,2016,28(12):1669-1672.
[3]方建明,张惠忠,黄建新，等.管状胃吻合预防近端胃切除术后反流性食管炎的临床研究[J]. 中华全科医学,2015,13(6):1030-1031.
[4]陈嘉伟,范志宁.抗反流手术在治疗胃食管反流疾病中的应用[J].医学研究生学报,2019,32(6):580-585.
[5]姚玉婷,尤彬彬,何飞等.咽喉反流性疾病临床诊疗探讨及心理评估[J].东南国防医药,2019,21(04):414-416.
[6]Abhinav K,Sunil D, Mekaroonkamol P, et al.Fluoroscopic gastric peroral endoscopic pyloromyotomy (G-POEM) in patients with a failed gastric electrical stimulator[J]. Gastroenterol Rep,2018,6(2)：122-126.
[7]Li L,Spandorfer R,Qu C, et al.Gastric per-oral endoscopic myotomy for refractory gastroparesis: a detailed description of the procedure, our experience, and review of the literature[J].Surg Endosc,2018,32(8)：3421-3431.
[8]赵伟,张其良,邓全军，等.Gerd Q量表联合24h食管PH监测诊断NERD的临床价值[J].武警后勤学院学报(医学版),2017,26(7):614-616.
[9]王兴坤.消化内科门诊胃食管反流病的临床分析[J].世界最新医学信息文摘,2019,19(21):64-65.
[10]李松霏,李文波,范飞飞，等.难治性胃食管反流病的治疗进展[J].胃肠病学,2017,22(7):439-442.
[11]李广华,叶锦宁,王昭，等.术后胃瘫的治疗进展[J].消化肿瘤杂志,2018,10(3):134-139.
[12]牟丹,苏庆革,于岩波，等.内镜下肌切开术在上消化道动力性疾病中的应用[J].腹腔镜外科杂志,2018,23(6):471-473.
[13]Mekaroonkamol P, Dacha S, Wang L, et al.Gastric Peroral Endoscopic Pyloromyotomy Reduces Symptoms, Increases Quality of Life, and Reduces Health Care Use For Patients With Gastroparesis[J]. Clin Gastroenterol Hepatol,2019,17(1):82-89.
[14]Xu J, Chen T, Elkholy S, et al.Gastric Peroral Endoscopic Myotomy (G-POEM) as a Treatment for Refractory Gastroparesis: Long-Term Outcomes[J]. Can J Gastroenterol Hepatol, 2018. doi: 10.1155/2018/6409698.
[15]Malik Z, Kataria R,Modayil R, et al.Gastric Per Oral Endoscopic Myotomy (G-POEM) for the Treatment of Refractory Gastroparesis: Early Experience[J].Dig Dis Sci，2018,63(9):2405-2412.
[16]何成海,应笑,高晨，等.经口内镜下幽门肌切开术治疗胃轻瘫二例[J].中华消化杂志,2019,39(11):786-788.

相似文献/References:

备注/Memo

备注/Memo:
基金项目：国家重点研发计划（2017YFC0908302）
更新日期/Last Update: 2021-06-17