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[1]胡雄辉,杨勇,李鑫,等.不同营养评分系统对胃癌根治术预后的预测价值分析[J].医学研究与战创伤救治(原医学研究生学报),2021,23(03):282-286.[doi:10.3969/j.issn.1672-271X.2021.03.013]
　HU Xiong-hui,YANG Yong,LI Xin,et al.Comparison of prognostic value of different nutritional scoring systems in patients with gastric cancer after radical gastrectomy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(03):282-286.[doi:10.3969/j.issn.1672-271X.2021.03.013]
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不同营养评分系统对胃癌根治术预后的预测价值分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年03期
页码:
282-286
栏目:
临床研究
出版日期:
2021-06-20

文章信息/Info

Title:
Comparison of prognostic value of different nutritional scoring systems in patients with gastric cancer after radical gastrectomy
作者:
胡雄辉; 杨勇; 李鑫; 蒲国士; 陈渝; 喻培
作者单位：635000达州，达州市中西医结合医院普通外科（胡雄辉、杨勇、李鑫、蒲国士、陈渝、喻培）
Author(s):
HU Xiong-hui; YANG Yong;  LI Xin; PU Guo-shi; CHEN Yu; YU Pei
（Department of General Surgery，Dazhou Integrated TCM & Western Medicine Hospital，Dazhou 635000，Sichuan，China）
关键词:
预后营养指数; 营养控制状态评分; 那不勒斯预后评分; 预后; 胃癌
Keywords:
prognostic nutritional index; controlling nutritional status; Naples prognostic score; prognosis; gastric cancer
分类号:
R735.2
DOI:
10.3969/j.issn.1672-271X.2021.03.013
文献标志码:
A
摘要:
目的比较预后营养指数（PNI）、营养控制状态评分（CONUT）、那不勒斯预后评分（NPS）在胃癌根治术后短期及长期预后中的预测价值。方法回顾性分析2009年1月至2014年6月在达州市中西医结合医院行胃癌根治术的218例患者临床病理资料，分析PNI、CONUT、NPS与术后并发症的关系，Kaplan-Meier法绘制生存曲线，用Cox比例风险模型进行单因素和多因素分析，计算受试者工作特征曲线（ROC）的曲线下面积，比较每个评分系统的预测能力。结果31例（14.2%）患者发生术后并发症，高CONUT和高NPS与术后严重并发症相关（P＜0.05）。Cox风险比例模型多因素分析发现，只有低PNI是总体生存的危险因素（P=0.031）。计算ROC曲线下面积显示PNI评分系统在胃癌术后5年生存的预测效能方面优于NPS及CONUT。结论CONUT、NPS在胃癌根治术患者术后短期预后预测效能方面优于PNI，对于高NPS和高CONUT患者需详细告知患者术后发生严重并发症风险。PNI在长期预后的预测效能中优于CONUT、NPS，可以在胃癌术后疗效的个体化预测与指导治疗中发挥重要作用。
Abstract:
ObjectiveTo evaluate the effects of three nutritional scoring systems (PNI，CONUT，NPS) on the short-or long-term prognosis of patients with gastric cancer who underwent radical gastrectomy.MethodsThe data of 218 gastric cancer patients who underwent radical gastrectomy at Dazhou integrated TCM&Western Medicine Hospital from January 2009 to June 2014 was retrospectively analyzed. Clinical pathological parameters, PNI, CONUT score, and NPS were collected and compared. We analysis the relationship of PNI, CONUT, NPS and postoperative complications. Survival curves were described by the Kaplan-Meier method. Univariate and multivariate analyses were performed using the Cox proportional hazards model to identify risk factors. The area under the receiver operating characteristic curve (AUC) was calculated to compare the predictive power of each scoring system.ResultsA total of 31 (14.2%) patients developed postoperative complications. High CONUT and high NPS were associated with severe postoperative complications（P＜0.05）. Multivariate analysis showed that only PNI was an independent risk factor for OS（P=0.031）. The area under the ROC curve showed that the prognostic efficiency of PNI was better than NPS and CONUT in 5-year OS.ConclusionCONUT and NPS are risk factors for short-term severe complications after gastric cancer radical gastrectomy. PNI is an independent risk factor that affects long-term survival after surgery, and its predictive efficiency is higher than CONTU and NPS.CONUT and NPS are better than PNI in predicting the short-term prognosis of patients after gastric cancer radical gastrectomy. For patients with high NPS and high CONUT, it is necessary to inform them of the risk of serious complications. PNI is superior to CONUT and NPS in predicting long-termprognosis, and can play an important role in individualized prediction and guiding treatment of postoperative efficacy of gastric cancer.

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更新日期/Last Update: 2021-06-17