|本期目录/Table of Contents|

[1]梁紫君,郑娜,张雪儿,等.外泌体与非痴呆型血管性认知障碍的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2021,23(04):401-406.[doi:10.3969/j.issn.1672-271X.2021.04.014]
　LIANG Zi-jun,ZHENG Na,ZHANG Xue-er,et al.Research progress of exosomes and vascular cognitive impairmentno dementia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2021,23(04):401-406.[doi:10.3969/j.issn.1672-271X.2021.04.014]
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外泌体与非痴呆型血管性认知障碍的研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第23卷
期数:
2021年04期
页码:
401-406
栏目:
综述
出版日期:
2021-08-10

文章信息/Info

Title:
Research progress of exosomes and vascular cognitive impairmentno dementia
作者:
梁紫君; 郑娜; 张雪儿; 安红伟
作者单位：530200南宁，广西中医药大学研究生院（梁紫君、张雪儿）；545001 柳州，柳州市中医医院神经内科（郑娜、安红伟）
Author(s):
LIANG Zi-jun1;  ZHENG Na2;  ZHANG Xue-er1 ;  AN Hong-wei2
(1. Graduate School, Guangxi University of Chinese Medicine, Nanning 530200, Guangxi, China; 2. Department of Neurology, Liuzhou Traditional Chinese Medical Hospital, Liuzhou 545001, Guangxi, China)
关键词:
非痴呆型血管性认知障碍; 外泌体; miRNA
Keywords:
vascular cognitive impairment no dementia;  exosome;  miRNA
分类号:
R743
DOI:
10.3969/j.issn.1672-271X.2021.04.014
文献标志码:
A
摘要:
非痴呆型血管性认知障碍（VCIND）是脑血管损伤所致的早期或轻度认知功能障碍，具有隐匿性和可逆性。外泌体能够介导神经血管单元内细胞间通讯和物质传递，特别是在基因表达中重要的调节作用的外泌体miRNA被广泛研究，在VCIND中扮演着重要角色。文章对外泌体在VCIND的发生发展过程的作用机制、诊断及治疗中的研究进展进行综述。
Abstract:
Vascular cognitive impairment no dementia (VCIND) is an early or mild cognitive impairment caused by cerebrovascular injury, which is latent and reversible. Exosomes can mediate intercellular communication and substance transfer within neurovascular units, especially exosomal miRNAs, which play an important regulatory role in gene expression, have been widely studied and play an important role in VCIND. This article reviews the mechanism, diagnosis and treatment of exosomes in the occurrence and development of VCIND.

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备注/Memo

备注/Memo:
基金项目：柳州市科技攻关与新产品试剂项目（2019BJ10611）
更新日期/Last Update: 2021-08-10