|本期目录/Table of Contents|

[1]陈艺,贾柯瑶,邓蓉,等.战创伤止血材料的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2022,24(4):397-402.[doi:10.3969/j.issn.1672-271X.2022.04.013]
 CHEN Yi,JIA Ke-yao,DENG Rong,et al.Advances in the study of the hemostatic materials for war trauma[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(4):397-402.[doi:10.3969/j.issn.1672-271X.2022.04.013]
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战创伤止血材料的研究进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年4期
页码:
397-402
栏目:
综述
出版日期:
2022-08-30

文章信息/Info

Title:
Advances in the study of the hemostatic materials for war trauma
作者:
陈艺贾柯瑶邓蓉程飚
作者单位:510010广州,南部战区总医院干部病房一科(陈艺);510515广州,南方医科大学临床医学系(贾柯瑶);510010广州,南部战区总医院健康医学科(邓蓉),烧伤整形科(程飚)
Author(s):
CHEN Yi1 JIA Ke-yao2 DENG Rong3 CHENG Biao4
(1. The First Cadre Ward, Southern Theatre Gerneral Hospital, Guangzhou 510010, Guangdong, China; 2.Clinical Medicine Department of Southern Medical University, Guangzhou 510515, Guangdong, China; 3. Health Medicine Ward, 4.Burn and Plastic Surgery Ward,
关键词:
战场和院前出血控制止血材料材料成分止血机制
Keywords:
battlefield and prehospital bleeding control hemorrhage materials material composition hemostatic mechanisms
分类号:
R826.1
DOI:
10.3969/j.issn.1672-271X.2022.04.013
文献标志码:
A
摘要:
失血是战创伤导致死亡的主要因素。战场上,受伤后能够快速有效止血对于挽救伤者生命至关重要。国内外军队已获准在战场上使用或有潜力用于院前环境中进行出血控制的止血材料,根据不同材料的成分差异所致的生化特性和止血机制的不同,各有优缺点,未来出血控制研究趋于材料微粒子纳米化、功能复合化的高智能更精准的发展方向。文章主要就止血材料在战创伤救治方面的应用进行综述,从而为战场和院前环境止血材料开发设计提供支持。
Abstract:
Blood loss is the main cause of leading cause of death from combat trauma.On the battlefield, rapid and effective hemostasis after an injury is essential to rescue the life of the wounded.The hemostatic materials that have been approved for use in the battlefield or have the potential to be used in pre-hospital environment for bleeding control,Each has its advantages and disadvantages of various materials according to the biochemical characteristics and hemostatic mechanisms caused by the differences in composition of different materials. Future hemorrhage control research tends to be the development direction of high intelligence and more accurate development of material particle nanoparticles and functional compositing.This article reviews the application of hemostatic materials in the treatment of war trauma, thus supporting the development and design of hemostatic materials in the battlefield and pre-hospital environment.

参考文献/References:

[1]Eastridge BJ, Mabry RL, Seguin P, et al. Death on the battlefield(2001-2011): implications for the future of combat casualty care[J]. J Trauma Acute Care Surg, 2012,73(6 Suppl 5):S431-S437.
[2]Sims K, Montgomery HR, Dituro P, et al. Management of External Hemorrhage in Tactical Combat Casualty Care: The Adjunctive Use of XStat Compressed Hemostatic Sponges: TCCC Guidelines Change 15-03[J]. J Spec Oper Med, 2016,16(1):19-28.
[3]Hickman DA, Pawlowski CL, Sekhon U, et al. Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding[J]. Adv Mater, 2018,30(4): 10.
[4]谈澄康. CS/PVA-海藻酸盐复合止血敷料的制备及性能研究[D]. 东华大学, 2020:81.
[5]Zimnitsky DS, Yurkshtovich TL, Bychkovsky P M. Multilayer adsorption of amino acids on oxidized cellulose[J]. J Colloid Interface Sci, 2005,285(2):502-508.
[6]钟善传,王丽,周斌,等.冻干血浆在平战时的应用与研究进展[J].东南国防医药,2022,24(3):310-314.
[7]Chapman MP, Moore EE, Moore HB, et al. Plasma-first resuscitation to treat haemorrhagic shock in urban areas - Authors’ reply[J]. Lancet, 2020,395(10224):562-563.
[8]Glassberg E, Nadler R, Gendler S, et al. Freeze-dried plasma at the point of injury: from concept to doctrine[J]. Shock, 2013,40(6):444-450.
[9]Shlaifer A, Siman-Tov M, Radomislensky I, et al. Prehospital administration of freeze-dried plasma, is it the solution for trauma casualties?[J] J Trauma Acute Care Surg, 2017,83(4):675-682.
[10]Garrigue D, Godier A, Glacet A, et al. French lyophilized plasma versus fresh frozen plasma for the initial management of trauma-induced coagulopathy: a randomized open-label trial[J]. J Thromb Haemost, 2018,16(3):481-489.
[11]Levy JH, Szlam F, Tanaka K A, et al. Fibrinogen and hemostasis: a primary hemostatic target for the management of acquired bleeding[J]. Anesth Analg, 2012,114(2):261-274.
[12]Innerhofer P, Fries D, Mittermayr M, et al. Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma(RETIC): a single-centre, parallel-group, open-label, randomised trial[J]. Lancet Haematol, 2017,4(6):e258-e271.
[13]Sanders S, Tien H, Callum J, et al. Fibrinogen Concentrate in the Special Operations Forces Environment[J]. Mil Med, 2018,183(1-2):e45-e50.
[14]Kheirabadi BS, Acheson EM, Deguzman R, et al. The potential utility of fibrin sealant dressing in repair of vascular injury inswine[J]. J Trauma, 2007,62(1):94-103.
[15]Chan V, Sarkari M, Sunderland R, et al. Platelets loaded with liposome-encapsulated thrombin have increased coagulability[J]. J Thromb Haemost, 2018,16(6):1226-1235.
[16]Lashof-Sullivan M, Shoffstall A, Lavik E. Intravenous hemostats: challenges in translation to patients[J]. Nanoscale, 2013,5(22):10719-10728.
[17]Modery-Pawlowski CL, Tian LL, Ravikumar M, et al. In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct[J]. Biomaterials, 2013,34(12):3031-3041.
[18]Lashof-Sullivan M, Holland M, Groynom R, et al. Hemostatic Nanoparticles Improve Survival Following Blunt Trauma Even after 1 Week Incubation at 50( degrees )C[J]. ACS Biomater Sci Eng, 2016,2(3):385-392.
[19]Lashof-Sullivan MM, Shoffstall E, Atkins KT, et al. Intravenously administered nanoparticles increase survival following blast trauma[J]. Proc Natl Acad Sci U S A, 2014,111(28):10293-10298.
[20]Peralta MR, Chowdary P. The use of new procoagulants in blunt and penetrating trauma[J]. Curr Opin Anaesthesiol, 2019,32(2):200-205.
[21]Spotnitz WD. Fibrin Sealant: The Only Approved Hemostat, Sealant, and Adhesive-a Laboratory and Clinical Perspective[J]. ISRN Surg, 2014,2014:203943.
[22]Butler FJ, Holcomb JB, Giebner SD, et al. Tactical combat casualty care 2007: evolving concepts and battlefield experience[J]. Mil Med, 2007,172(11 Suppl):1-19.
[23]Gegel B, Burgert J, Gasko J, et al. The effects of QuikClot Combat Gauze and movement on hemorrhage control in a porcine model[J]. Mil Med, 2012,177(12):1543-1547.
[24]Bennett BL, Littlejohn L. Review of new topical hemostatic dressings for combat casualty care[J]. Mil Med, 2014,179(5):497-514.
[25]Peng HT, Grodecki R, Rizoli S, et al. A comparative study of tissue factor and kaolin on blood coagulation assays using rotational thromboelastometry and thromboelastography[J]. Blood Coagul Fibrinolysis, 2016,27(1):31-41.
[26]张宜, 张梦, 刘学会,等. 美军高岭土止血材料的研究进展[J]. 华南国防医学杂志,2014, 28(12): 1275-1277.
[27]Ran Y, Hadad E, Daher S, et al. QuikClot Combat Gauze use for hemorrhage control in military trauma: January 2009 Israel Defense Force experience in the Gaza Strip--a preliminary report of 14 cases[J]. Prehosp Disaster Med, 2010,25(6):584-588.
[28]Brown MA, Daya MR, Worley JA. Experience with chitosan dressings in a civilian EMS system[J]. J Emerg Med, 2009,37(1):1-7.
[29]Sohn VY, Eckert MJ, Martin MJ, et al. Efficacy of three topical hemostatic agents applied by medics in a lethal groin injury model[J]. J Surg Res, 2009,154(2):258-261.
[30]Te GR, van Grunsven PM, Heutz WM, et al. Prehospital use of hemostatic dressings in emergency medical services in the Netherlands: A prospective study of 66 cases[J]. Injury, 2016,47(5):1007-1011.
[31]Valeri CR, Vournakis JN. mRDH bandage for surgery and trauma: data summary and comparative review[J]. J Trauma, 2011,71(2 Suppl 1):S162-S166.
[32]Casey BJ, Behrens AM, Hess JR, et al. FVII dependent coagulation activation in citrated plasma by polymer hydrogels[J]. Biomacromolecules, 2010,11(12):3248-3255.
[33]Hsu BB, Conway W, Tschabrunn CM, et al. Clotting Mimicry from Robust Hemostatic Bandages Based on Self-Assembling Peptides[J]. ACS Nano, 2015,9(9):9394-9406.
[34]Lin WC, Tseng CH, Yang MC. In-vitro hemocompatibility evaluation of a thermoplastic polyurethane membrane with surface-immobilized water-soluble chitosan and heparin[J]. Macromol Biosci, 2005,5(10):1013-1021.
[35]Sambasivan CN, Cho SD, Zink KA, et al. A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine[J]. Am J Surg, 2009,197(5):576-580.
[36]Englehart MS, Cho SD, Tieu BH, et al. A novel highly porous silica and chitosan-based hemostatic dressing is superior to HemCon and gauze sponges[J]. J Trauma, 2008,65(4):884-892.
[37]Chan LW, White NJ, Pun SH. A Fibrin Cross-linking Polymer Enhances Clot Formation Similar to Factor Concentrates and Tranexamic Acid in an in vitro Model of Coagulopathy[J]. ACS Biomater Sci Eng, 2016,2(3):403-408.
[38]Lamm RJ, Lim EB, Weigandt KM, et al. Peptide valency plays an important role in the activity of a synthetic fibrin-crosslinking polymer[J]. Biomaterials, 2017,132:96-104.
[39]史跃,朱卉琪,张琦,等.创伤急救止血贴的研制及应用研究[J].东南国防医药,2019,21(2):219-221.
[40]张平, 肖南, 张治纲,等. 战创伤止血敷料的现状及展望[J]. 创伤外科杂志,2009, 11(4):378-380.
[41]Peng X, Xia X, Xu X, et al. Ultrafast self-gelling powder mediates robust wet adhesion to promote healing of gastrointestinal perforations[J]. Sci Adv, 2021,7(23).
[42]笪虎,焦峰,陈顺宝,等.新型弹力加压敷料在门急诊出血性损伤救治中的应用[J].东南国防医药,2015,17(3):266-268.
[43]董永喜, 刘星星, 董莉,等. 白及多糖对血热出血模型大鼠的止血作用及机制研究[J]. 中国药房,2016, 27(31):4347-4350.
[44]赵菲菲, 杨馨, 徐丹,等. 白及非多糖组分的止血作用及其机制的初步研究[J]. 中国药理学通报,2016, 32(8):1121-1126.
[45]刘星星, 董莉, 张晓红,等. 止血生物效价用于白及品质评价的研究[J]. 中国中药杂志,2014, 39(19):3764-3767.

相似文献/References:

[1]史跃,朱卉琪,张琦,等.创伤急救止血贴的研制及应用研究[J].医学研究与战创伤救治(原医学研究生学报),2019,21(02):219.[doi:10.3969/j.issn.1672-271X.2019.02.027]

备注/Memo

备注/Memo:
基金项目:军队后勤科研项目(CLB21C025);军事医学创新工程专项(18CXZ029)
更新日期/Last Update: 2022-09-06