|本期目录/Table of Contents|

[1]牛盈盈,焦明克.脉冲电磁场对组织创伤修复效果的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2022,24(4):418-422.[doi:10.3969/j.issn.1672-271X.2022.04.017]
　NIU Ying-ying,JIAO Ming-ke.Progress of pulsed electromagnetic fields’ effect on tissue wound repair[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(4):418-422.[doi:10.3969/j.issn.1672-271X.2022.04.017]
点击复制

脉冲电磁场对组织创伤修复效果的研究进展()
分享到62.8K

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年4期
页码:
418-422
栏目:
综述
出版日期:
2022-08-30

文章信息/Info

Title:
Progress of pulsed electromagnetic fields’ effect on tissue wound repair
作者:
牛盈盈; 焦明克
作者单位：830000乌鲁木齐,新疆医科大学研究生院(牛盈盈);830000乌鲁木齐,新疆军区总医院医学工程科(焦明克)
Author(s):
NIU Ying-ying1 ;  JIAO Ming-ke2
(1.Xinjiang Medical University, Urumqi 830000, Xinjiang, China; 2. Department of Biomedical Engineering, General Hospital of Xinjiang Military Area Command, Urumqi 830000, Xinjiang, China)
关键词:
脉冲电磁场; 组织修复; 创面愈合; 生物效应; 作用机制
Keywords:
pulsed electromagnetic fields(PEMF);  tissue repair;  wound healing;  biological effect;  mechanism of action
分类号:
R641
DOI:
10.3969/j.issn.1672-271X.2022.04.017
文献标志码:
A
摘要:
大量研究证实脉冲电磁场（PEMF）具有促进组织再生修复的作用，且部分相关结果已应用于临床，效果显著。因此对PEMF生物效应在组织创伤修复方面的研究进展进行较全面的归纳分析具有重要意义。文章主要简述了PEMF在不同类型组织、细胞修复再生方面的应用研究成果，归类分析PEMF的生物效应机制，并对PEMF生物效应在组织细胞修复再生方面的研究提出了较为科学的构思和设想，为拓展PEMF在临床的应用提供了相应的理论依据。
Abstract:
A large number of studies have confirmed that pulsed electromagnetic fields (PEMF) can promote tissue repair, and some related studies have achieved remarkable results with being applied to clinical practice. Therefore, it is important to analyze and summarize the advances of the biological effects of PEMF on tissue wound repair. Initially, the applied research results of PEMF are described in the repair of different tissues. Besides, the mechanism of biological effects of PEMF is analyzed. At last, a scientific conception for the research of PEMF on tissue repair is put forward and provides a possible theoretical basis for expanding the application of PEMF.

参考文献/References:

[1]付小兵. 组织修复与再生的新挑战:实现多种组织在损伤部位的同步修复与再生[J]. 中华烧伤杂志, 2016,32(1):6-10.
[2]Ross CL, Ang DC, Almeida-Porada G. Targeting Mesenchymal Stromal Cells/Pericytes(MSCs) With Pulsed ElectromagneticField(PEMF) Has the Potential to Treat Rheumatoid Arthritis[J]. Front Immunol, 2019,10:266.
[3]Bassett CA, Pawluk RJ, Pilla AA. Augmentation of bone repair by inductively coupled electromagnetic fields[J]. Science, 1974,184(4136):575-577.
[4]Zhang B, Xie Y, Ni Z, et al. Effects and Mechanisms of Exogenous Electromagnetic Field on Bone Cells: A Review[J]. Bioelectromagnetics, 2020,41(4):263-278.
[5]Catalano A, Loddo S, Bellone F, et al. Pulsed electromagnetic fields modulate bone metabolism via RANKL/OPG and Wnt/β-catenin pathways in women with postmenopausal osteoporosis: A pilot study[J]. Bone, 2018,116(23):42-46.
[6]马丽萍, 王剑火, 姜绪防. 碳酸钙维生素D_3及鲑鱼降钙素联合脉冲电磁场治疗老年女性骨质疏松症的临床观察[J]. 东南国防医药, 2013,15(2):154-156.
[7]Streit A, Watson BC, Granata JD, et al. Effect on Clinical Outcome and Growth Factor Synthesis With Adjunctive Use of Pulsed Electromagnetic Fields for Fifth Metatarsal Nonunion Fracture[J]. Foot Ankle Int, 2016,37(9):919-923.
[8]Bagnato GL, Miceli G, Marino N, et al. Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial[J]. Rheumatology, 2016,55(4):755-762.
[9]Martini F, Pellati A, Mazzoni E, et al. Bone Morphogenetic Protein-2 Signaling in the Osteogenic Differentiation of HumanBone Marrow Mesenchymal Stem Cells Induced by Pulsed Electromagnetic Fields[J]. Int J Mol Sci, 2020,21(6):2104.
[10]Suryani L, Too JH, Hassanbhai AM, et al. Effects of Electromagnetic Field on Proliferation, Differentiation, and Mineralization of MC3T3 Cells[J]. Tissue Eng Part C Methods, 2019,25(2):114-125.
[11]Uzun C, Erdal N, Gürgül S, et al. Comparison of the Effects of Pulsed Electromagnetic Field and Extracorporeal Shockwave Therapy in a Rabbit Model of Experimentally Induced Achilles Tendon Injury[J]. Bioelectromagnetics, 2021,42(2):128-145.
[12]Anbarasan S, Baraneedharan U, Paul SF, et al. Low dose short duration pulsed electromagnetic field effects on cultured human chondrocytes: An experimental study[J]. Indian J Orthop, 2016,50(1):87-93.
[13]梁卫, 董国刚, 刘梅, 等. 创伤生肌水凝胶对动物皮肤创伤的愈合作用[J]. 东南国防医药, 2021,23(2):117-121.
[14]Khooshideh M, Latifi RSS, Sheikh M, et al. Pulsed Electromagnetic Fields for Postsurgical Pain Management in Women Undergoing Cesarean Section: A Randomized, Double-Blind, Placebo-controlled Trial[J]. Clin J Pain, 2017,33(2):142-147.
[15]Rohde CH, Taylor EM, Alonso A, et al. Pulsed Electromagnetic Fields Reduce Postoperative Interleukin-1β, Pain, and Inflammation: A Double-Blind, Placebo-Controlled Study in TRAM Flap Breast Reconstruction Patients[J]. Plast Reconstr Surg, 2015,135(5):808-817.
[16]Patruno A, Ferrone A, Costantini E, et al. Extremely low-frequency electromagnetic fields accelerates wound healing modulating MMP-9 and inflammatory cytokines[J]. Cell Prolif, 2018,51(2):e12432.
[17]Harry MCC, Alex KKC, Gabriel YFN, et al. Effects of pulsed electromagnetic field(PEMF) on the tensile biomechanical properties of diabetic wounds at different phases of healing[J]. PLoS One, 2018,13(1):e208475.
[18]霍博, 丁元钧, 蔡婧, 等. 低强度脉冲电磁场加速2型糖尿病表皮软组织创伤愈合实验[J]. 中国医学物理学杂志, 2020,37(7):912-917.
[19]Selvam A, Ulaganathan B, Solomon FP, et al. Low dose short duration pulsed electromagnetic field effects on cultured human chondrocytes: An experimental study[J]. Indian J Orthop, 2016,50(1):87-93.
[20]Jiao M, Lou L, Jiao L, et al. Effects of low-frequency pulsed electromagnetic fields on plateau frostbite healing in rats[J]. Wound Repair Regen, 2016,24(6):1015-1022.
[21]焦明克, 王芳利, 胡劼, 等. 低频脉冲电磁场对大鼠应激性溃疡胃壁血液循环及超微结构的影响[J]. 医疗卫生装备, 2018,39(5):35-38.
[22]Jiao M, Yin H, Hu J, et al. Effects of Low-Frequency Pulsed Electromagnetic Fields on High-Altitude Stress UlcerHealing in Rats[J]. Biomed Res Int, 2019,2019:6354054.
[23]陈清云, 林频容, 谢雨濛, 等. 表面肌电技术指导下督脉电针治疗脑卒中下肢痉挛的临床价值[J]. 东南国防医药, 2020,22(5):477-480.
[24]NaRi S, Sung-Ho L, Kyung WJ, et al. Low-frequency pulsed electromagnetic field pretreated bone marrow-derived mesenchymal stem cells promote the regeneration of crush-injured rat mental nerve[J]. Neural Regen Res, 2018,13(1):145-153.
[25]张理乾, 徐春归, 李子煜, 等. 低频脉冲电磁场促进周围神经损伤模型大鼠延迟修复后神经功能的恢复[J]. 中国组织工程研究, 2019,23(11):1711-1716.
[26]Li Z, Yao F, Cheng L, et al. Low frequency pulsed electromagnetic field promotes the recovery of neurological function after spinal cord injury in rats[J]. J Orthop Res, 2019,37(2):449-456.
[27]Wu S, Yu Q, Lai A, et al. Pulsed electromagnetic field induces Ca2+-dependent osteoblastogenesis in C3H10T1/2 mesenchymal cells through the Wnt-Ca2+/Wnt-β-catenin signaling pathway[J]. Biochem Biophys Res Commun, 2018,503(2):715-721.
[28]邵佳乐, 李志忠, 周建, 等. 低频脉冲电磁场通过IGF-1R/NO信号通路促进大鼠颅骨成骨细胞成熟及矿化[J]. 浙江大学学报(医学版), 2019,48(2):158-164.
[29]Pall ML. Electromagnetic field activation of voltage-gated calcium channels: role in therapeutic effects[J]. Electromagn Biol Med, 2014,33(4):251.
[30]Wang Y, Pu X, Shi W, et al. Pulsed electromagnetic fields promote bone formation by activating the sAC-cAMP-PKA-CREB signaling pathway[J]. J Cell Physiol, 2019,234(3):2807-2821.
[31]Bagheri L, Pellati A, Rizzo P, et al. Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields[J]. J Tissue Eng Regen Med, 2018,12(2):304-315.
[32]Peng L, Fu C, Liang Z, et al. Pulsed Electromagnetic Fields Increase Angiogenesis and Improve Cardiac Function After Myocardial Ischemia in Mice[J]. Circ J, 2020,84(2):186-193.
[33]Vincenzi F, Pasquini S, Setti S, et al. Pulsed Electromagnetic Fields Stimulate HIF-1α-Independent VEGF Release in 1321N1 Human Astrocytes Protecting Neuron-Like SH-SY5Y Cells from Oxygen-Glucose Deprivation[J]. Int J Mol Sci, 2020,21(21):8053.
[34]Erica C, Bruna S, Chiara DA, et al. Human Gingival Fibroblasts Exposed to Extremely Low-Frequency Electromagnetic Fields: In Vitro Model of Wound-Healing Improvement[J]. Int J Mol Sci, 2019,20(9):2108.
[35]Vinhas A, Rodrigues MT, Gonalves AI, et al. Pulsed Electromagnetic Field Modulates Tendon Cells Response in IL-1β-Conditioned Environment[J]. J Orthop Res, 2020,38(1):160-172.
[36]Alessandra C, Perucca OC, Vincenzi F, et al. A2A adenosine receptors are involved in the reparative response of tendon cells to pulsed electromagnetic fields[J]. PLoS One, 2020,15(9):e239807.
[37]Thomas AW, Kevin MV. Macrophages in Tissue Repair, Regeneration, and Fibrosis[J]. Immunity, 2016,44(3):450-462.
[38]Adriana V, Ana FA, Ana IG, et al. Magnetic Stimulation Drives Macrophage Polarization in Cell to-Cell Communication with IL-1β Primed Tendon Cells[J]. Int J Mol Sci, 2020,21(15):5441.

相似文献/References:

[1]马丽萍,王剑火,姜绪防,等.碳酸钙维生素D_3及鲑鱼降钙素联合脉冲电磁场治疗老年女性骨质疏松症的临床观察[J].医学研究与战创伤救治(原医学研究生学报),2013,15(02):154.
　.Health-center of Fuzhou Tenth Cadres Sanatorium of Fujian Povincial Military District,Fuzhou,Fujian 000,et al.MA Li-ping 1,WANG Jian-huo 2,JIANG Xu-fang 3[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2013,15(4):154.
[2]张少波,温春虹,何杰综述,等.巨噬细胞极化分型与创伤修复的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2018,20(04):390.[doi:10.3969/j.issn.1672-271X.2018.04.014]

备注/Memo

备注/Memo:
-
更新日期/Last Update: 2022-09-06