|本期目录/Table of Contents|

[1]鲁毅,贾奕扬,段靖,等.环维黄杨星D新型纳米递药系统的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2022,24(5):524-527.[doi:10.3969/j.issn.1672-271X.2022.05.016]
 LU Yi,JIA Yi-yang,DUAN Jing,et al.Recent progress of novel nano-drug delivery system of Cyclovirobuxine D[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2022,24(5):524-527.[doi:10.3969/j.issn.1672-271X.2022.05.016]
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环维黄杨星D新型纳米递药系统的研究进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第24卷
期数:
2022年5期
页码:
524-527
栏目:
综述
出版日期:
2022-11-02

文章信息/Info

Title:
Recent progress of novel nano-drug delivery system of Cyclovirobuxine D
作者:
鲁毅贾奕扬段靖刘梅
作者单位:210002南京,东部战区空军医院药剂科(鲁毅、贾奕扬、段靖、刘梅)
Author(s):
LU Yi JIA Yi-yang DUAN Jing LIU Mei
(Department of Pharmacy, the Air Force Hospital of Eastern Theater Command, Nanjing 210002, Jiangsu, China)
关键词:
环维黄杨星D纳米药物递药系统
Keywords:
Cyclovirobuxine D nanodrug drug delivery systems
分类号:
R28
DOI:
10.3969/j.issn.1672-271X.2022.05.016
文献标志码:
A
摘要:
环维黄杨星D (CVB-D)属于一种孕甾烷类生物碱,在临床上治疗心血管方面的疾病具有良好的疗效,近期也有研究表明其具有抗肿瘤活性。CVB-D水溶性差、生物利用度较低等问题严重限制了其应用范围。因此对CVB-D进行药物制剂学改造,如新型纳米递药系统,改善CVB-D溶解度,提高治疗效果,降低其毒副作用具有重要的意义。近年围绕环维黄杨宁D的纳米递药系统进行了大量研究,文章主要对CVB-D新型纳米递药系统的研究进展进行综述。
Abstract:
Cyclovirobuxine D is the progesterone alkaloids, which has good therapeutic effect in the treatment of cardiovascular diseases, and recent studies have also shown that it has certain anti-tumor activity. However, the application of Cyclovirobuxine D is limited by its poor water solubility and low bioavailability. Therefore, it is of great significance for the treatment of pharmaceutical engineering of Cyclovirobuxine D, such as novel nano-drug delivery system, to improve the solubility and therapeutic effect and reduce its toxicity and side effects. Recently, a large number of studies have been carried out on the nano-drug delivery systems of Cyclovirobuxine D and the research progress of novel nano-drug delivery systems of Cyclovirobuxine D is reviewed in this paper.

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备注/Memo

备注/Memo:
基金项目:南京市药学会基金(2019YX002)
更新日期/Last Update: 2022-11-16