|本期目录/Table of Contents|

[1]周建丽,吴巧珍.OSAHS合并2型糖尿病肾病的相关机制研究进展[J].医学研究与战创伤救治(原医学研究生学报),2023,25(1):85-89.[doi:10.3969/j.issn.1672-271X.2023.01.017]
 ZHOU Jianli,WU Qiaozhen.Advances of the mechanisms associated with obstructive sleep apnea hypopnea syndrome with type 2 diabetic nephropathy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2023,25(1):85-89.[doi:10.3969/j.issn.1672-271X.2023.01.017]
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OSAHS合并2型糖尿病肾病的相关机制研究进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第25卷
期数:
2023年1期
页码:
85-89
栏目:
综述
出版日期:
2023-05-10

文章信息/Info

Title:
Advances of the mechanisms associated with obstructive sleep apnea hypopnea syndrome with type 2 diabetic nephropathy
作者:
周建丽吴巧珍
作者单位:226000南通,南通大学医学院(周建丽);215000苏州,苏州大学附属苏州九院(苏州市第九人民医院)呼吸与危重症医学科(吴巧珍)
Author(s):
ZHOU Jianli1 WU Qiaozhen2
(1. Medical College of Nantong University, Nantong 226000, Jiangsu, China;2.Department of Respiratory and Critical Care Medicine,Soochow Ninth Hospital Affiliated to Suzhou University, Soochow Ninth People′s Hospital, Soochow 215000, Jiangsu, China)
关键词:
阻塞性睡眠呼吸暂停低通气综合征2型糖尿病糖尿病肾脏疾病相关机制
Keywords:
obstructive sleep apnea hypopnea syndrometype 2 diabetesdiabetic kidney diseasethe relevant mechanism
分类号:
R563.8R587.1
DOI:
10.3969/j.issn.1672-271X.2023.01.017
文献标志码:
A
摘要:
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是2型糖尿病(T2DM)公认的危险因素。T2DM合并多种血管并发症,糖尿病肾病是其中较为严重且多见的一种,糖尿病肾病患者往往合并阻塞性睡眠呼吸暂停,两者之间存在强相关性。文章主要就OSAHS与2型糖尿病肾损伤的相关机制研究进行综述。
Abstract:
Obstructive sleep apneahypopnea syndrome (OSAHS) is a recognized risk factor for type 2 diabetes (T2DM). T2DM can be associated with a variety of vascular complications, of which diabetic kidney disease is one of the more serious and common ones. Patients with diabetic nephropathy tend to have obstructive sleep apnea, which have strong correlations. This review mainly summarizes the research progress on the correlation between OSA and renal injury in patients with type 2 diabetes.

参考文献/References:

[1]Rundo JV. Obstructive sleep apnea basics[J]. Cleve Clin J Med, 2019,86(9 Suppl 1):2-9.
[2]苏小凤,刘霖,仲琳,等.中国阻塞性睡眠呼吸暂停综合征患病率的Meta分析[J]. 中国循证医学杂志, 2021,21(10):1187-1194.
[3]Benjafield AV, Ayas NT, Eastwood PR, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis[J]. Lancet Respir Med, 2019,7(8):687-698.
[4]American Diabetes Association.2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021[J]. Diabetes Care, 2021,44(Suppl 1):S15-S33.
[5]Rayego-Mateos S, Morgado-Pascual JL, Opazo-Ríos L, et al. Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy[J]. Int J Mol Sci, 2020,21(11):3798.
[6]Al Mawed S, Unruh M. Diabetic kidney disease and obstructive sleep apnea: a new frontier?[J] Curr Opin Pulm Med, 2016,22(1):80-88.
[7]Lin C, Lurie RC, Lyons OD. Sleep Apnea and Chronic Kidney Disease: A State-of-the-Art Review[J]. Chest, 2020,157(3):673-685.
[8]Zamarrón E, Jaureguizar A, García-Sánchez A, et al. Obstructive sleep apnea is associated with impaired renal function in patients with [J]. Sci Rep, 2021,11(1):5675.
[9]Nishimura A, Kasai T, Kikuno S, et al. Effect of Sleep-Disordered Breathing on Albuminuria in 273 Patients With Type 2 Diabetes[J]. J Clin Sleep Med, 2018,14(3):401-407.
[10]Siwasaranond N, Nimitphong H, Manodpitipong A, et al. The Relationship between Diabetes-Related Complications and Obstructive Sleep Apnea in Type 2 Diabetes[J]. J Diabetes Res, 2018,2018:9269170.
[11]Zamarrón E, Jaureguizar A, García-Sánchez A, et al. Obstructive sleep apnea is associated with impaired renal function in patients with diabetic kidney disease[J]. Sci Rep, 2021,11(1):5675.
[12]Xue P, Covassin N, Ran X, et al. Association of parameters of nocturnal hypoxemia with diabetic microvascular [J]. Diabetes Res Clin Pract, 2020,170:108484.
[13]Nishimura A, Kasai T, Matsumura K, et al. Obstructive sleep apnea during rapid eye movement sleep in patients with diabetic [J]. J Clin Sleep Med, 2021,17(3):453-460.
[14]Abuyassin B, Badran M, Ayas N T, et al. Intermittent hypoxia causes histological kidney damage and increases growth factor expression in a mouse model of obstructive sleep apnea[J]. PLoS One, 2018,13(2):e192084.
[15]Strausz S, Havulinna AS, Tuomi T, et al. Obstructive sleep apnoea and the risk for coronary heart disease and type 2 diabetes: a longitudinal population-based study in Finland[J]. BMJ Open, 2018,8(10):e22752.
[16]Lin Y, Chang Y, Yang S, et al. Update of pathophysiology and management of diabetic kidney disease[J]. J Formos Med Assoc, 2018,117(8):662-675.
[17]Wu X, Pan Z, Liu W, et al. The Discovery, Validation, and Function of Hypoxia-Related Gene Biomarkers for Obstructive Sleep Apnea[J]. Front Med (Lausanne), 2022,9:813459.
[18]Jha JC, Banal C, Chow BSM, et al. Diabetes and Kidney Disease: Role of Oxidative Stress[J]. Antioxid Redox Signal, 2016,25(12):657-684.
[19]Pérez-Torres I, Soto ME, Manzano-Pech L, et al. Oxidative Stress in Plasma from Patients with Marfan Syndrome Is Modulated by Deodorized Garlic Preliminary Findings[J]. Oxid Med Cell Longev, 2022,2022:5492127.
[20]Cannavò L, Perrone S, Viola V, et al. Oxidative Stress and Respiratory Diseases in Preterm Newborns[J]. Int J Mol Sci, 2021,22(22).
[21]Charlton A, Garzarella J, Jandeleit-Dahm KAM, et al. Oxidative Stress and Inflammation in Renal and Cardiovascular Complications of Diabetes[J]. Biology (Basel), 2020,10(1):18.
[22]Maniaci A, Iannella G, Cocuzza S, et al. Oxidative Stress and Inflammation Biomarker Expression in Obstructive Sleep Apnea Patients[J]. J Clin Med, 2021,10(2).
[23]Bhatt SP, Guleria R, Kabra SK. Metabolic alterations and systemic inflammation in overweight/obese children with obstructive sleep apnea[J]. PLoS One, 2021,16(6):e252353.
[24]Chen P, Chiu W, Hsu P, et al. Pathophysiological implications of hypoxia in human diseases[J]. J Biomed Sci, 2020,27(1):63.
[25]Quercioli A, Mach F, Montecucco F. Inflammation accelerates atherosclerotic processes in obstructive sleep apnea syndrome (OSAS)[J]. Sleep Breath, 2010,14(3):261-269.
[26]Elmarakby AA, Sullivan JC. Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy[J]. Cardiovasc Ther, 2012,30(1):49-59.
[27]Dinh QN, Drummond GR, Sobey CG, et al. Roles of inflammation, oxidative stress, and vascular dysfunction in hypertension[J]. Biomed Res Int, 2014,2014:406960.
[28]Cheng H, Harris RC. Renal endothelial dysfunction in diabetic nephropathy[J]. Cardiovasc Hematol Disord Drug Targets, 2014,14(1):22-33.
[29]Yu W, Wang X, Ni Y, et al. Association of OSAHS Hypoxia Indicators with Early Renal Injury and Serum Fibroblast Growth Factor 21 in Obese Type 2 Diabetic Patients[J]. Diabetes Ther, 2019,10(4):1357-1368.
[30]Voulgaris A, Bonsignore MR, Schiza S, et al. Is kidney a new organ target in patients with obstructive sleep apnea? Research priorities in a rapidly evolving field[J]. Sleep Med, 2021,86:56-67.
[31]Jin Z,Wei Y. Meta-analysis of effects of obstructive sleep apnea on the renin-angiotensin-aldosterone system[J]. J Geriatr Cardiol, 2016,13(4):333-343.
[32]Patel DM, Bose M, Cooper ME. Glucose and Blood Pressure-Dependent Pathways-The Progression of Diabetic Kidney Disease[J]. Int J Mol Sci, 2020,21(6).
[33]Ruggenenti P, Cravedi P, Remuzzi G. The RAAS in the pathogenesis and treatment of diabetic nephropathy[J]. Nat Rev Nephrol, 2010,6(6):319-330.
[34]Rimke AN, Ahmed SB, Turin TC, et al. Effect of CPAP therapy on kidney function in patients with obstructive sleep apnoea and chronic kidney disease: a protocol for a randomised controlled clinical trial[Z]. BMJ Open,2019, 9(3):e024632.
[35]Kennedy C, Ryan SA, Kane T, et al. The impact of change of renal replacement therapy modality on sleep quality in patients with end-stage renal disease: a systematic review and meta-analysis[J]. J Nephrol, 2018,31(1):61-70.
[36]Beecroft J, Duffin J, Pierratos A, et al. Enhanced chemo-responsiveness in patients with sleep apnoea and end-stage renal disease[J]. Eur Respir J, 2006,28(1):151-158.
[37]Harmon RR, De Lima JJG, Drager LF, et al. Obstructive sleep apnea is associated with interdialytic weight gain and increased long-term cardiovascular events in hemodialysis patients[J].Sleep Breath,2018,22(3):721-728.
[38]Lin C,Perger E, Lyons OD. Obstructive sleep apnea and chronic kidney disease[J]. Curr Opin Pulm Med, 2018,24(6):549-554.
[39]Jhamb M, Ran X, Abdalla H, et al. Association of Sleep Apnea with Mortality in Patients with Advanced Kidney Disease[J]. Clin J Am Soc Nephrol, 2020,15(2):182-190.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2023-04-19