[1] Nowbar AN,Gitto M,Howard JP,et al.Mortality from IschemicHeart Disease[J].Circ Cardiovasc Qual Outcomes,2019,12(6):e005375.[2] Oikonomou EK,Desai MY,Marwan M,et al.Perivascular Fat At?tenuation Index Stratifies Cardiac Risk Associated with High-Risk Plaques in the CRISP-CT Study[J]. J Am Coll Cardiol,2020,76(6): 755-757.[3] Gao M,Tang M,Ho W,et al.Modulating plaque inflammation viatargeted mRNA nanoparticles for the treatment of atherosclerosis[J].ACS Nano,2023,17(18): 17721-17739.[4] 刘晓滢,江杰,李俊,等.基于CT冠状动脉周围脂肪测量对冠状动脉非钙化斑块风险分层的价值初探[J].放射学实践,2023,38(7): 879-883.[5] 张龙江,乔红艳.冠状动脉CT——从解剖学迈入功能学的新时代[J].医学研究生学报,2019,32(3): 225-229.[6] Yu X,Botezatu S,Tzolos E,et al.Pericoronary adipose tissue CTattenuation in coronary artery plaque inflammation[J]. Heart,2023,109(6): 485-493.[7] AjoolabadyA,PraticoD,VinciguerraM,et al.Inflammaging:Mech?anisms and role in the cardiac and vasculature[J].Trends Endo?crinol Metab,2023,34(6): 373-387.[8] Kinoshita D,Suzuki K,Yuki H,et al.Sex-specific association be?tween perivascular inflammation and plaque vulnerability[J].Circ Cardiovasc Imaging,2024,17(2): e016178.[9] Antonopoulos AS,Sanna F,Sabharwal N,et al.Detecting HumanCoronary Inflammation by Imaging Perivascular Fat[J]. SciTransl Med,2017,9(398): eaal2658.[10] Honold S,Wildauer M,Beyer C,et al.Reciprocal communicationof pericoronary adipose tissue and coronary atherogenesis[J].Eur J Radiol,2021,136: 109531.[11] Corvera S,Solivan-Rivera J,Yang Loureiro Z.Angiogenesis in ad?ipose tissue and obesity[J].Angiogenesis,2022,25(4): 439-453.[12] Marketou M,Lazopoulos G,Kontaraki J,et al.PPAR- γ gene ex?pression in pericoronary adipose tissue: A focus on obesity[J].Hellenic J Cardiol,2023,69: 67-68.[13] 庄微,孔娜娜,刘挺松,等.晚期糖基化终末产物受体在波动性高糖致人冠状动脉内皮细胞凋亡中的作用[J].医学研究与战创伤救治,2024,37(5): 482-487.[14] Goeller M,Achenbach S,Duncker H,et al.Imaging of the Peri?coronary Adipose Tissue(PCAT)Using Cardiac Computed To?mography: Modern Clinical Implications[J].J Thorac Imaging,2021,36(3): 149-161.[15] Hillock-Watling C,Gotlieb AI.The pathobiology of perivascularadipose tissue(PVAT),the fourth layer of the blood vessel wall[J].Cardiovasc Pathol,2022,61: 107459.[16] Xie Y,Jin H,Zeng M,et al.Coronary Artery Plaque Imaging[J].Curr Atheroscler Rep,2017,19(9): 37.[17] Oikonomou EK,Marwan M,Desai MY,et al.Non-invasive detec?tion of coronary inflammation using computed tomography andprediction of residual cardiovascular risk(the CRISP CT study):a post-hoc analysis of prospective outcome data[J]. Lancet,2018,392(10151): 929-939.[18] 周茜洋,唐春香,张龙江,等.残余炎性心血管风险的研究进展[J].医学研究生学报,2020,33(7): 760-764.[19] Kurata A.Deep learning-based CT noise reduction for perivascu?lar adipose tissue evaluation[J].Acad Radiol,2024,31(2): 446-447.[20] Crewe C,An YA,Scherer PE.The ominous triad of adipose tis?sue dysfunction: Inflammation,fibrosis,and impaired angiogene?sis[J].J Clin Invest,2017,127(1): 74-82.[21] Adachi Y,Ueda K,Nomura S,et al.Beiging of perivascular adi?pose tissue regulates its inflammation and vascular remodeling[J].Nat Commun,2022,13(1): 5117.[22] 王芳,夏雨薇,柴象飞,等.影像组学分析流程及临床应用的研究进展[J].中华解剖与临床杂志,2021,26(2): 236-241.[23] Oikonomou EK,Williams MC,Kotanidis CP,et al.A Novel Ma?chine Learning-Derived Radiotranscriptomic Signature of Peri?vascular Fat Improves Cardiac Risk Prediction Using CoronaryCT angiography[J].Eur Heart J,2019,40(43): 3529-3543.[24] Almeida S,Pelter M,Shaikh K,et al.Feasibility of MeasuringPericoronary Fat from Precontrast Scans: Effect of Iodinated Con?trast on Pericoronary Fat Attenuation[J].J Cardiovasc ComputTomogr,2020,14(6): 490-494.[25] Chen XJ,Dang YX,Hu H,et al.Pericoronary Adipose Tissue At?tenuation Assessed by Dual-Layer Spectral Detector ComputedTomography Is a Sensitive Imaging Marker of High-Risk Plaques[J].Quant Imaging Med Surg,2021,11(5): 2093-2103.[26] Ma R,Ties D,van Assen M,et al.Towards reference values ofpericoronary adipose tissue attenuation: Impact of coronary ar?tery and tube voltage in coronary computed tomography angiogra?phy[J].Eur Radiol,2020,30(12): 6838-6846.[27] Kwiecinski J,Tzolos E,Williams MC,et al.Noninvasive Coro?nary Atherosclerotic Plaque Imaging[J].JACC Cardiovasc Imag?ing,2023,16(12): 1608-1622.[28] Tan N,Dey D,Marwick TH,et al.Pericoronary Adipose Tissueas a Marker of Cardiovascular Risk: JACC Review Topic of the Week[J].J Am Coll Cardiol,2023,81(9): 913-923.[29] Giesen A,Mouselimis D,Weichsel L,et al.Pericoronary AdiposeTissue Attenuation Is Associated with Non-Calcified Plaque Bur?den in Patients with Chronic Coronary Syndromes[J].J Cardio?vasc Comput Tomogr,2023,17(6): 384-392.[30] Goeller M,Tamarappoo B,Kwan A,et al.Increased PericoronaryAdipose Tissue Attenuation Is Related To Progression Of Coro?nary Plaque Burden Quantified From Coronary Ct Angiography[J].J Cardiovasc Comput Tomogr,2019,13(1): S34.[31] Yang S,Hoshino M,Koo BK,et al.Relationship of plaque fea?tures at coronary CT to coronary hemodynamics and cardiovascu?lar events[J].Radiology,2022,305(3): 578-587.[32] Chen R,Li X,Jia H,et al.Radiomics analysis of pericoronary ad?ipose tissue from baseline coronary computed tomography angi?ography enables prediction of coronary plaque progression[J].JThorac Imaging,2024,39(6): 359-366.[33] Tzolos E,Williams MC,McElhinney P,et al.Pericoronary adi?pose tissue attenuation,low-attenuation plaque burden and 5-year risk of myocardial infarction[J].JACC Cardiovasc Imaging,2022,15(6): 1078-1088.[34] Araki M,Di Mario C,Guagliumi G,et al.Optical coherence to?mography in coronary atherosclerosis assessment and interven?tion[J].Nat Rev Cardiol,2022,19(10): 684-703.[35] Sugiyama T,Kanaji Y,Hoshino M,et al.Relationship betweenpericoronary adipose tissue attenuation on computed tomographyangiography and coronary plaque characteristics on optical co?herence tomography[J].J Am Coll Cardiol,2020,75(11,Supple?ment 1): 1385.[36] Kim JN,Gomez-Perez L,Zimin VN,et al.Pericoronary AdiposeTissue Radiomics from Coronary Computed Tomography Angiog?raphy Identifies Vulnerable Plaques[J].Bioengineering(Basel),2023,10(3): 360.[37] Zhang X,Cao Z,Xu J,et al.Peri-coronary fat attenuation indexcombined with high-risk plaque characteristics quantified fromcoronary computed tomography angiography for risk stratificationin new-onset chest pain individuals without acute myocardial in?farction[J].PLoS One,2024,19(5): e0304137.[38] Kwiecinski J,Tzolos E,Adamson PD,et al.Coronary 18F-sodiumfluoride uptake predicts outcomes in patients with coronary ar?tery disease[J].J Am Coll Cardiol,2020,75(24): 3061-3074.[39] Kwiecinski J,Tzolos E,Meah MN,et al. Machine learningwith 18F-sodium fluoride PET and quantitative plaque analysison CT angiography for the future risk of myocardial infarction[J].J Nucl Med Off Publ Soc Nucl Med,2022,63(1): 158-165.[40] Kwiecinski J,Dey D,Cadet S,et al.Peri-Coronary Adipose Tis?sue Density Is Associated With 18F-Sodium Fluoride CoronaryUptake in Stable Patients With High-Risk Plaques[J]. JACCCardiovasc Imaging,2019,12(10): 2000-2010.[41] Wang KL,Balmforth C,Meah MN,et al.Coronary atheroscleroticplaque activity and risk of myocardial infarction[J].J Am CollCardiol,2024,83(22): 2135-2144.[42] Chen M,Hao G,Hu S,et al.Lesion-specific pericoronary adiposetissue CT attenuation improves risk prediction of major adversecardiovascular events in coronary artery disease[J].Br J Radiol,2024,97(1153): 258-266.[43] Liu M,Zhen Y,Shang J,et al.The predictive value of lesion-spe?cific pericoronary fat attenuation index for major adverse cardio?vascular events in patients with type 2 diabetes[J].CardiovascDiabetol,2024,23(1): 191.[44] Zou L,Xiao X,Jia Y,et al.Predicting coronary atherosclerosisheart disease with pericoronary adipose tissue attenuation param?eters based on dual-layer spectral detector computed tomogra?phy: A preliminary exploration[J]. Quant Imaging Med Surg,2023,13(5): 2975-2988.[45] Cheng S,Ni J,Deng W,et al.Diagnostic ability of perivascularfat attenuation index in predicting atherosclerotic plaque forma?tion proximal to myocardial bridging of the left anterior descend?ing artery within 3 years[J].Acad Radiol,2023,30(10): 2234-2242.[46] Dawson LP,Lum M,Nerleker N,et al.Coronary AtheroscleroticPlaque Regression: JACC State-of-the-Art Review[J].J Am CollCardiol,2022,79(1): 66-82.[47] Libby P.The Changing Landscape of Atherosclerosis[J].Nature,2021,592(7855): 524-533.[48] Dai X,Yu L,Lu Z,et al.Serial change of perivascular fat attenua?tion index after statin treatment: Insights from a coronary CT an?giography follow-up study[J].Int J Cardiol,2020,319: 144-149.[49] Mátyás BB,Benedek I,Rat N,et al.Assessing the impact of longtermhigh-dose statin treatment on pericoronary inflammationand plaque distribution- a comprehensive coronary CTA followupstudy[J].Int J Mol Sci,2024,25(3): 1700.