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[1]刘英娜,冷冬妮,闵 慧.胰腺实性假乳头状瘤临床病理分析[J].医学研究与战创伤救治(原医学研究生学报),2009,11(02):127-130.
　LIU Ying-na,LENG Dong-ni,MIN Hui.Clinicopathological analysis of solid-pseudopapillary tumors of the pancreas[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2009,11(02):127-130.
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胰腺实性假乳头状瘤临床病理分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第11卷
期数:
2009年02期
页码:
127-130
栏目:
出版日期:
2009-03-20

文章信息/Info

Title:
Clinicopathological analysis of solid-pseudopapillary tumors of the pancreas
文章编号:
1672-271X(2009)02-0127-04
作者:
刘英娜; 冷冬妮; 闵 慧
解放军第454医院病理科，江苏南京 210002
Author(s):
LIU Ying-na;  LENG Dong-ni;  MIN Hui
Department of Pathology, the 454th Hospital of PLA, Nanjing 210002, Jiangsu,China
关键词:
胰腺实性假乳头状瘤; 临床病理; 鉴别诊断
Keywords:
Solid-pseudopapillary tumors of the pancreas; Clinicopathology; Differential diagnosis
分类号:
R735.9
DOI:
-
文献标志码:
A
摘要:
目的 研究胰腺实性假乳头状瘤(SPT)病理诊断和鉴别诊断。方法 采用HE和免疫组化(EnVision法)观察13例胰腺实性假乳头状瘤。结果 13例患者中11例为女性，2例为男性，年龄12～65岁，平均32岁，随访8例，手术后均无复发。肿瘤平均直径约7 cm，有包膜。组织学上肿瘤呈实性或假乳头两种排列方式。免疫组化:β-catenin核阳性10例，α1-AT阳性13例，Vimentin阳性13例，CD10阳性10例，PR阳性9例，CKpan阳性2例，Syn阳性1例，CgA阳性1例。结论 SPT是一种较少见的胰腺低度恶性肿瘤，须与胰腺其他多种肿瘤进行鉴别诊断。
Abstract:
Objective To study the pathological diagnosis and differential diagnosis of solid-pseudopapillary tumors of the pancreas (SPT).Methods 13 cases of SPT were investigated with HE staining and EnVision immunostaining.Results 7 patients were young females and 2 were adult males, 12 to 65 years in age (mean 32 years). Eight patients were followed up and none recurred after tumor resection. The tumors were mean diameter 7 cm in size, all encapsulated. Histologically, all cases showed presence of solid sheets or pseudopapillary structure. Immunohistochemically, the tumors were positive for β-catenin (nuclear) (10/13), α1-AT (13/13), Vimentin (13/13), CD10 (10/13), PR (9/13), CKpan (2/13), Syn (1/13) and CgA (1/13).Conclusin The SPT is a rare low-grade malignant tumor of the pancreas.It is important to differentiate SPT from many other tumors of the pancreas.

参考文献/References:

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[8]Martin RC,Klimstra DS,Brennan MF,et al.Solid-pseudopap- illary tumor of the pancreas: a surgical enigma[J].Ann Surg Oncol, 2002,9(1):35-40.
[9]Donatella S,Francesca P,Stefania L.Solid-papillary tumors of the pancreas:histopathology [J].J Pancreas,2006,7(1):131-136.
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备注/Memo:
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更新日期/Last Update: 2013-11-20