[1]吴金飞,陈传琳,曾素琴,等.脑梗死危险因素及生化特征分析[J].医学研究与战创伤救治(原医学研究生学报),2014,16(03):270-272.[doi:10.3969/j.issn.1672-271X.2014.03.014]
　WU Jin-fei,CHEN Chuan-lin,ZENG Su-qin,et al.Risk factors and biochemical indicators of cerebral infarction[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2014,16(03):270-272.[doi:10.3969/j.issn.1672-271X.2014.03.014]
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脑梗死危险因素及生化特征分析()

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第16卷
期数:
2014年03期
页码:
270-272
栏目:
出版日期:
2014-05-20

文章信息/Info

Title:
Risk factors and biochemical indicators of cerebral infarction
作者:
吴金飞; 陈传琳; 曾素琴; 熊 宁
335000 江西鹰潭，解放军184医院心脑血管科
Author(s):
WU Jin-fei; CHEN Chuan-lin; ZENG Su-qin; XIONG Ning.
Cardiovascular and Cerebrovascular Department，184 Hospital of PLA，Yingtan,Jiangxi 335000，China
关键词:
脑梗死; 危险因素; 生化特征
Keywords:
cerebral infarction;  risk factors;  biochemical indicator
分类号:
R681
DOI:
10.3969/j.issn.1672-271X.2014.03.014
文献标志码:
A
摘要:
目的 探讨脑梗死发病的危险因素及生化指标特征。方法 采用回顾性调查方法，将调查对象分为脑梗死组(165例)与对照组(66例)，通过Logistic回归分析、t检验方法对数据进行处理。结果 单因素Logistic回归分析中，年龄、吸烟史、高血压史、糖尿病史与脑梗死发病密切相关(P<0.05)；组间比较t检验分析中，急性期脑梗死组白细胞计数高于非急性期组对照组(P<0.05)，脑梗死患者中性粒细胞百分比、C反应蛋白、转脂蛋白a、总胆固醇、低密度脂蛋白胆固醇、血糖均高于对照组(P<0.05)。结论 血脂、血糖、血压异常增高及吸烟是导致发病的确切危险因素，脑梗死病变初期伴明显的炎性反应，倡导健康的饮食、生活习惯及对血压、血糖、血脂的管理有助于预防脑梗死的发病，脑梗死发病初期需积极抑制炎性反应。
Abstract:
Objective To explore risk factors,biochemical indicators of cerebral infarction.Methods A retrospective analysis including 165 patients with cerebral infarction divided into acute group and non-acute group and 66 control subjects were carried out.The descriptive statistics,t test were used in the study of biochemical indicators of cerebral infarction,logistic regression analysis were used in the study for comparing the risk factors.Results According to the results of single-factor logistic regression analysis,sex,age,smoking history,hypertension history,diabetes were closely correlated with the occurrence of cerebral infarction (P<0.05).According to the results of t test,the WBC of patients with cerebral infarction in acute group was significant higher than WBC of patients in non-acute group and control group (P<0.05).The percentage of GRAN,and levels of CRP,LPA,TC,LDL-C and GLU of patients with cerebral infarction were significant higher than that of patients in the control group (P<0.05).Conclusion Abnormal blood lipids,increased blood glucose level,increased blood pressure and the smoking were confirmed risk factors of cerebral infarction,the inflammatory reaction during initial stage of cerebral infarction,reasonable diet,healthy life style as well as the good management of the underlying disease were significant measures for prevention of cerebral infarction.On the early stage of cerebral infarction should inhibit the inflammatory reaction.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2014-05-20