|本期目录/Table of Contents|

[1]戴卉,张暐,缪小红,等.中性粒细胞/淋巴细胞比值联合营养风险筛查对老年肌少症患者的诊断价值[J].医学研究与战创伤救治(原医学研究生学报),2023,25(3):242-246.[doi:10.3969/j.issn.1672-271X.2023.03.004]
　DAI Hui,ZHANG Wei,MIAO Xiaohong,et al.The diagnostic value of neutrophil/lymphocyte ratio combined with nutritional risk screening in senile patients with sarcopenia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2023,25(3):242-246.[doi:10.3969/j.issn.1672-271X.2023.03.004]
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中性粒细胞/淋巴细胞比值联合营养风险筛查对老年肌少症患者的诊断价值()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第25卷
期数:
2023年3期
页码:
242-246
栏目:
临床研究
出版日期:
2023-08-01

文章信息/Info

Title:
The diagnostic value of neutrophil/lymphocyte ratio combined with nutritional risk screening in senile patients with sarcopenia
作者:
戴卉; 张暐; 缪小红; 黄莹; 陈茜; 滕士超
作者单位：210029南京，南京中医药大学附属医院（江苏省中医院）老年医学科（戴卉、张暐、缪小红、黄莹、陈茜、滕士超）
Author(s):
DAI Hui;  ZHANG Wei;  MIAO Xiaohong;  HUANG Ying;  CHEN Qian;  TENG Shichao
(Department of Geriatric Medicine, Affillated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine, Nanjing 210029, Jiangsu, China )
关键词:
老年患者; 肌少症; 中性粒细胞/淋巴细胞比值; 影响因素
Keywords:
elderly patients;  sarcopenia;  neutrophil-to-lymphocyte ratio;  factors affecting
分类号:
R592
DOI:
10.3969/j.issn.1672-271X.2023.03.004
文献标志码:
A
摘要:
目的探究中性粒细胞/淋巴细胞比值（NLR）及营养风险筛查（NRS2002）对老年患者肌少症的诊断价值。方法回顾性分析江苏省中医院老年病科收治的160例老年住院患者的临床资料，依据是否为肌少症分为肌少症组75例和非肌少症组85例。收集患者临床资料，采用单因素、多因素非条件性Logistic回归分析肌少症发生的影响因素，绘制受试者工作特征（ROC）曲线分析其诊断价值，分析肌少症患者NLR水平与NRS2002评分的相关性。结果单因素分析显示，肌少症组与非肌少症组年龄、NRS2002评分、握力、步速、骨骼肌质量指数(ASMI)、血清白蛋白（Alb）、血红蛋白（Hb）及NLR比较，差异有统计学意义（P＜0.05）；多因素非条件性Logistic回归分析显示，年龄（95%CI：1.036~1.126）、NRS2002（95%CI：1.043~2.093）和NLR（95%CI：1.006~1.373）是老年患者发生肌少症的影响因素；NLR联合NRS2002对患者发生肌少症预测的ROC曲线下面积（AUC）为0.730，敏感度为0.835，特异度为0.533；肌少症患者NLR水平与NRS2002评分呈正相关（r=0.439，P＜0.001）。结论NLR水平及NRS2002评分是老年患者发生肌少症的影响因素，NLR联合NRS2002对老年患者发生肌少症具有一定预测价值。
Abstract:
ObjectiveTo investigate the diagnostic value of neutrophil-to-lymphocyte ratio (NLR) and nutritional risk screening (NRS2002) on the elderly patients with sarcopenia.Methods160 elderly inpatients admitted to the Geriatrics Department of Jiangsu Hospital of Traditional Chinese Medicine were selected and their clinical data were collected. According to the diagnostic criteria of sarcopenia, they were divided into sarcopenia group (75 cases) and non-sarcopenia group (85 cases). Univariate and multivariate unconditional logistic regression were used to analyze the factors affecting the occurrence of sarcopenia. Receiver operating characteristic (ROC) curve was used to analyze its diagnostic value. The correlation between the level of NLR and the score of NRS2002 in sarcopenia patients was analyzed.ResultsUnivariate analysis showed that there were significant differences between age, NRS2002 scores, grip strength, pace, ASMI, Alb, Hb and NLR between the sarcopenia group and the non-sarcopenia group (P<0.05). Multivariate unconditional Logistic regression analysis showed that age (95%CI：1.036-1.126), NRS2002 (95% CI：1.043-2.093) and NLR (95%CI：1.006-1.373) were the influencing factors for the occurrence of sarcopenia in elderly patients. The area under the curve (AUC), sensitivity and specificity of NLR combined with NRS2002 for sarcopenia were 0.730, 0.835 and 0.533. The level of NLR in sarcopenia patients was positively correlated with the score of NRS2002 (r=0.439, P＜0.001).ConclusionThe level of NLR and NRS2002 score are influencing factors for the occurrence of sarcopenia in elderly patients, and the combination of NLR and NRS2002 have certain predictive value for the occurrence of sarcopenia in elderly patients.

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备注/Memo

备注/Memo:
基金项目：江苏省卫生健康委科研课题项目（BJ20020）
更新日期/Last Update: 2023-08-24