|本期目录/Table of Contents|

[1]周 源,汪 栋,张传生,等.肺癌患者术前病理诊断的临床意义[J].医学研究与战创伤救治(原医学研究生学报),2008,10(02):97.
　ZHOU Yuan,WANG Dong,ZHANG Chuan-sheng,et al.Clinical significance of preoperatively pathological diagnosis of lung cancer[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2008,10(02):97.
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肺癌患者术前病理诊断的临床意义()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第10卷
期数:
2008年02期
页码:
97
栏目:
出版日期:
2008-03-20

文章信息/Info

Title:
Clinical significance of preoperatively pathological diagnosis of lung cancer
文章编号:
1672-271X(2008)02-0097-03
作者:
周 源; 汪 栋; 张传生; 韩开宝; 叶玉坤
解放军第81医院全军肿瘤中心胸心外科，江苏南京 210002
Author(s):
ZHOU Yuan; WANG Dong; ZHANG Chuan-sheng;  HAN Kai-bao;  YE Yu-kun
Department of Cardiothoracic Surgery, the 81th Hospital of PLA, Nanjing 210002,Jiangsu,China
关键词:
外科; 肺癌; 术前; 病理诊断
Keywords:
Lung caner;  Surgery;  Pathological diagnosis
分类号:
R734.2
DOI:
-
文献标志码:
A
摘要:
目的 探讨外科治疗肺癌患者术前明确病理诊断的临床意义。方法 回顾性分析2000年1月~2005年1月本科治疗585例肺癌的临床及病理资料。结果 经术前病理检查确诊肺癌529例，占外科治疗肺癌患者的90.4%(529/585)；其中诊断小细胞肺癌62例，均给予2周期术前新辅助化疗，有效率82.3 %(51/62)，4例达到组织学完全缓解(6.5%)。36例局部晚期非小细胞肺癌给予1~2周期新辅助化疗，有效率55.6 %(20/36)。结论 肺癌术前病理诊断是分期综合治疗的前提；明确病理诊断为局限期小细胞肺癌和局部晚期非小细胞肺癌是术前新辅助化疗的根本依据。
Abstract:
Objective To evaluate the clinical significance of preoperatively pathological diagnosis in the surgical management of lung cancer.Methods The clinical and pathological data of 585 patients with primary lung cancer from Jan,2000 to Jan,2005 were analyzed retrospectively.Results 529 cases were pathologically diagnosed before operation, which counted for 90.4% (529/585) of total patients surgically treated for the primary lung cancer. Neoadjuvant chemotherapy (NAC) for two cycles was given to 62 patients who were diagnosed as small cell lung cancer (SCLC) before operation, in which effective rate was 82.3% (51/62) and 4 patients histologically completely relieved (6.5%). One or two cycles of neoadjuvant chemotherapy were given to 36 patients with local advanced non-small cell lung cancer (NSCLC), in which effective rate was 55.6% (20/36).Conclusion Preoperative pathological diagnosis is necessary for the staging and comprehensive treatment of lung cancer. Preoperative Neoadjuvant chemotherapy for localized SCLC and advanced local NSCLC is based on definitely pathological diagnosis.

参考文献/References:

[1]董先伟,乔友林,李连弟,等.中国癌症控制策略研究报告[J].中国肿瘤,2002, 11(5):250-260.
[2]吴一龙,张明和,廖美琳,等.肺癌的诊断和分期临床指引[J].中国肺癌杂志,2003,6(5):330-333.
[3]Hoffmann H.Resected non-small-cell lung cancer stage Ⅰ/Ⅱ:indication for adjuvant/neoadjuvant therapy[J]. Lung Cancer, 2004, 45 (Suppl 2):S91-S97.
[4]Nakamura H, Kato Y, Kato H. Outcome of surgery for small cell lung cancer - response to induction chemotherapy predicts survival[J]. Thorac Cardiovasc Surg, 2004, 52(4):206-210.
[5]Rosell R, Felip E. Role of multimodality treatment for lung cancer[J]. Semin Surg Oncol, 2000, 18(2):143-151.
[6]周清华,刘伦旭,李 潞,等.术前新辅助化疗加外科手术治疗Ⅲ期非小细胞肺癌的随机对照临床研究[J].中国肺癌杂志,2001, 4(4):251-256.
[7]Junker K. Therapy-induced morphological changes in lung cancer[J]. Pathologe, 2004, 25(6):475-480.
[8]黄国俊,张德超,毛友生,等.肺癌的临床分期与外科病理TNM分期比较[J].中华肿瘤杂志,2005, 27(9):551-553.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-11-22