|本期目录/Table of Contents|

[1]陆月明,秦玉波,丁小丽.支原体肺炎临床特征的研究[J].医学研究与战创伤救治(原医学研究生学报),2009,11(04):308-309,315.
　LU Yue-ming,QING Yu-bo,DING Xiao-Li.Analysis of clinical characteristics of Mycoplasma pneumonia[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2009,11(04):308-309,315.
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支原体肺炎临床特征的研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第11卷
期数:
2009年04期
页码:
308-309,315
栏目:
出版日期:
2009-07-20

文章信息/Info

Title:
Analysis of clinical characteristics of Mycoplasma pneumonia
文章编号:
1672-271X(2009)04-0308-03
作者:
陆月明1; 秦玉波1; 丁小丽2
1.解放军第455医院呼吸科，上海200052；2.空军上海后勤训练基地门诊部,上海200052
Author(s):
LU Yue-ming;  QING Yu-bo;  DING Xiao-Li
Department of Respiratroy Medicine, the 455th Hopsital of PLA, Shanghai 200052, China
关键词:
肺炎支原体; 肺炎; 临床特征
Keywords:
Mycoplasma pnuemoniae;  Pneumonia;  Clinical feature
分类号:
R375.2
DOI:
-
文献标志码:
A
摘要:
目的观察13例支原体肺炎患者临床特征及胸部影像学改变。 方法对13例因发热住院的患者分别应用逆转录-聚合酶链反应检测咽漱液中常见上呼吸道病原体DNA，应用免疫荧光法检测血清中常见上呼吸道病原体IgM抗体；同时进行胸部X线和CT检查。 结果13例患者肺炎支原体-IgM抗体阳性，临床主要表现为发热和干咳，胸部X线片表现为小片状密度增高影，CT表现为两肺多发或单发性斑片状密度增高影，仅1例呈大片状模糊影。阿齐霉素治疗效果较好。 结论支原体肺炎有一定的传染性，临床症状较重，但体征缺乏特异性，胸部CT扫描较普通X线胸片更易发现病灶，血清IgM抗体检查有助于支原体肺炎的临床诊断。
Abstract:
ObjectiveTo investigate the clinical features and changes of the chest imaging characteristics of patients with Mycoplasma pneumonia. MethodsA prospective study for Mycoplasma pneumoniae infection in 13 patients with high fever was carried out. Throat washing fluid specimen were detected for common respiratory pathogens by reverse transcription polymerase chain reactions. Immunoglobulin M (IgM) to common respiratory pathogens in serum samples were detected by immunofluorescene tests. Chest X-ray and computed tomography for all the patients with fever were studied during hospitalizations. ResultsThe major symptoms of the patients were high fever and dry cough. Serum IgM to Mycoplasma pneumoniae was positive in all patients. The most common imaging presentations were unilateral and (or) bilateral multi-focal or solitary patchy opacities in 13 patients. Pulmonary consolidation was found only in one patient. Azithromycin therapy was effective for all patients. ConclusionThe patients with Mycoplasma pneumonia were contagiousness, their symptoms were severe, but no special physical signs were found. Chest computer tomograhy scan is a more sensitive technique for observation of Mycoplasma pneumonia than chest X-ray examination. Serum IgM test is a useful method for diagnosis of Mycoplasma pnuemoniea infection.

参考文献/References:

[1]陆慰萱. 呼吸系疾病诊断与诊断评析[M]. 上海:上海科学技术出版社, 2004: 172-175.
[2]Kashyap B, Kumar S, Sethi GR, et al. Comparison of PCR, culture & serological tests for the diagnosis of mycoplasma pneumoniae in community-acquired lower respiratory tract infections in children [J]. Indian J Med Res, 2008, 128(2):134-139.
[3]Ngeow YF, Suwanjutha S, Chantarojanasriri T, et al. An Asian study on the prevalence of atypical respiratory pathogens in community-acquired pneumonia [J]. Int J Infect Dis, 2005，9(1):144-153.
[4]刘又宁, 陈民均, 赵铁梅, 等. 中国城市成人社区获得性肺炎665例病原学多中心调查[J]. 中华结核和呼吸杂志, 2006, 29(1): 3-7.
[5]Martínez MA, Ruiz M, Zunino E, et al. Detection of mycoplasma pneumoniae in adult community-acquired pneumonia by PCR and serology [J]. J Med Microbiol, 2008, 57( 12):1491-1495.
[6]Dégrange S, Cazanave C, Charron A, et al. Development of multiple-locus variable-number tandem-repeat analysis for molecular typing of Mycoplasma pneumoniae [J]. J Clin Microbiol, 2009, 47(4): 914-923.
[7]Sung RY, Chan PK, Tsen T, et al. Identification of viral and atypical bacterial pathogens in children hospitalized with acute respiratory infections in Hong Kong by multiplex PCR assays [J]. J Med Virol, 2009,81(1):153-159.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2013-11-20