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[1]金 玲,富丹萍,金 晶.高血压患者颈动脉粥样硬化与血清C-肽、唾液酸的关系[J].医学研究与战创伤救治(原医学研究生学报),2011,13(01):34-36.
 JIN Ling,FU Dan-ping,JIN Jing.The relation between carotid atherosclerosis and serum C-peptide and sialic acid in hypertensive patients[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(01):34-36.
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高血压患者颈动脉粥样硬化与血清C-肽、唾液酸的关系()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年01期
页码:
34-36
栏目:
出版日期:
2011-01-20

文章信息/Info

Title:
The relation between carotid atherosclerosis and serum C-peptide and sialic acid in hypertensive patients
文章编号:
1672-271X(2011)01-0034-03
作者:
金 玲富丹萍金 晶
310002 浙江杭州,南京军区杭州疗养院海勤疗养区特诊科
Author(s):
JIN LingFU Dan-pingJIN Jing
Naval Convalescent Zone, Hangzhou Sanatorium of Nanjing Military Command,Hangzhou,Zhejiang 310002,China
关键词:
高血压病颈动脉粥样硬化 C-肽唾液酸
Keywords:
hypertension carotid atherosclerosis C-peptide sialic acid
分类号:
R544.11
DOI:
-
文献标志码:
A
摘要:
目的 探讨原发性高血压(EH)患者颈动脉粥样硬化(CAS)与C-肽、唾液酸的关系。方法 收集50例EH伴CAS患者和43例EH不伴CAS患者的人体学指标、既往史、实验室检测和骨密度检查数据,进行统计学分析。结果 EH伴CAS组与EH不伴CAS组比较, C-肽、唾液酸、胰岛素、C反应蛋白、血尿酸、年龄、舒张压、脉压差、吸烟、冠心病和骨质疏松发生率等因素差异有统计学意义(P<0.05),多因素分析显示,年龄、吸烟(少量)、唾液酸和C-肽是CAS的独立危险因素。结论 EH患者C-肽、唾液酸等指标与CAS关系密切,并参与了CAS的发生发展。
Abstract:
Objective To investigate the relation between carotid atherosclerosis (CAS) in essential hypertension (EH) patients and C-peptide and sialic acid. Methods The main anthropometry index, past medical history, the data of laboratory detection and bone mineral density from 50 EH cases with CAS and 43 EH cases without CAS were collected and analyzed statistically. Results There were significant difference in C-peptide, SA, INS, CRP, UA, age, DBP, PP, smoking, coronary heart disease and the prevalence of osteoporosis between the group of 50 EH cases with CAS and 43 EH without CAS cases (P<0.05). The age, smoking, SA and C-peptide were the independent risk factors after multivariate analysis. Conclusion There is a close relationship between carotid atherosclerosis of hypertensive patients and serum C-peptide, sialic acid. These factors are involved in the development of CAS.

参考文献/References:

[1]周永昌,郭万学.超声医学[M].4版.北京:科学技术文献出版社,2002:802.
[2]刘忠厚,杨定焯,朱汉民,等.中国人原发性骨质疏松症诊断标准(试行)[J].中国骨质疏松杂志,1999,5(3):1-2.
[3]唐海江,张曙云.颈动脉超声检查动脉硬化的临床价值[J].东南国防医药,2008,10(5):331-332.
[4]李桂芹,杨金奎,李明珠.不同病程中C-肽与2型糖尿病微血管病变的相关性[J].中国微循环,2009,13(1):38-41.
[5]朱 梅,吴 国.原发性高血压和冠心病患者胰岛素和C-肽的临床观察[J].放射免疫学杂志,2006,19(5):359-361.
[6] Mantique C,Lastra G,Whaley-Comnell A, et al.Hypertension and the cardiometabolic syndrome[J].Clin Hypertens(Greenwich),2005,7(8):471.
[7]Gracheva EV, Samovilova NN, Golovanova NK,et al.Sialytransferase activity of human plasma and aortic intima is enhanced in atherosclerosis[J].Biochim Biophys Acta,2002,1586(1):123-128.
[8]Tertov VV,Nikonova EY,Nifantev NE,et al.Human plasma trans-sialidase donor and acceptor specificity[J].Biochemistry(Mose),2002,67(8):908-913.
[9]王育珊,张艳杰,张 东,等.急性心肌梗死患者血清唾液酸水平变化及意义[J].中华急诊医学杂志,2004,13(6):410-411.
[10] Linda WH,Hsueh WC,Rainwater DL,et al.Family history of type2 diatetes is associated with increased carotid artery intima medial thickness in Mexican anlerfoans[J].Diabetes Care,2007,99(1):99-102.
[11]薛 冰,李清贤,孙景芝.老年冠心病患者100例血清hs-CRP、IL-6、和IL-18的检测及临床意义[J].中国老年学杂志,2010,4(30):997-998.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-01-20