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[1]邵 洁,陈邦元,李 雯,等.早期肠内营养对休克后患者炎性反应的疗效研究[J].医学研究与战创伤救治(原医学研究生学报),2011,13(03):226-227.
　SHAO Jie,CHEN Bang-yuan,LI Wen,et al.Study of the effects of early enteral nutrition on the inflammatory response after shock[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(03):226-227.
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早期肠内营养对休克后患者炎性反应的疗效研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年03期
页码:
226-227
栏目:
出版日期:
2011-05-20

文章信息/Info

Title:
Study of the effects of early enteral nutrition on the inflammatory response after shock
文章编号:
1672-271X(2011)03-0226-02
作者:
邵 洁1; 陈邦元1; 李 雯2; 刘 峰1
1．212001 江苏镇江，解放军359医院检验科；2．212003 江苏镇江，江苏省军区镇江军分区第三干休所
Author(s):
SHAO Jie1; CHEN Bang-yuan1; LI Wen2; LIU Feng1.
1. Department of Clinical Laboratory, 359 Hospital of PLA, Zhenjiang, Jiangsu 212001，China; 2. Zhenjiang Military Subarea No.3 Retired Cadre Unit of Jiangsu Provincial Military District，Zhenjiang，Jiangsu 212003, China
关键词:
休克; 早期肠内营养; 内毒素; 肿瘤坏死因子-α; 全身炎性反应综合征
Keywords:
shock;  early enteral nutrition;  endotoxin;  tumor necrosis fator-α(TNF-α);  systemic inflammatory response syndrome
分类号:
R541.64
DOI:
-
文献标志码:
A
摘要:
目的 研究早期肠内营养(EN)对休克患者内毒素及肿瘤坏死因子-α(TNF-α)的作用及全身炎性反应综合征(SIRS)的影响。方法 休克67例随机分为早期EN组和肠外营养(TPN)组，检测两组患者肠内营养治疗前、治疗后1、3、5 d血浆中内毒素与TNF-α水平；统计两组SIRS的持续时间与多器官功能障碍(MODS)的发生率。结果 早期EN组患者5 d后血浆内毒素与TNF-α明显低于TPN组(P<0.01)，SIRS的持续时间与MODS的发病率均低于TPN组(P<0.05)。结论 早期肠内营养可显著降低休克后患者血浆内毒素及TNF-α水平，缩短了SIRS的持续时间，降低了MODS的发生率。
Abstract:
Objective To study the therapeutic effects of early enteral nutrition on the serum endotoxin, tumor necrosis fator-α (TNF-α) and systemic inflammatory response syndrome (SIRS) of patients after shock. Methods Sixty-seven patients were randomly divided into early enteral nutrition group and total parenteral nutrition (TPN) group after shock. The serum endotoxin and TNF-α level were detected at 0 d, 1 d, 3 d and 5 d respectively. The duration of SIRS and the morbidity rates of multiple organ dysfunction syndrome (MODS) were compared between two groups. Results The serum endotoxin and TNF-α level of patients suffered from shock in EN group were obviously lower than those in TPN group after 5 days(P<0.01). The duration of SIRS and the morbidity rates of MODS in EN group were lower than those in TPN group(P<0.05). Conclusion Early enteral nutrition can decrease the serum endotoxin and TNF-α level in shock patients, which is redound to attenuate the SIRS and decrease morbidity the rate of MODS.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-05-20