[1]胡星星,周楚瑶,钟正江,等.适应性支持通气在COPD合并呼吸衰竭患者的应用[J].医学研究与战创伤救治(原医学研究生学报),2011,13(05):412-414.
　HU Xing-xing,ZHOU Chu-yao,ZHONG Zheng-jiang,et al.Clinical application of adaptive support ventilation on patients with chronic obstructive pulmonary disease complicating respiratory failure[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2011,13(05):412-414.
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适应性支持通气在COPD合并呼吸衰竭患者的应用()

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第13卷
期数:
2011年05期
页码:
412-414
栏目:
出版日期:
2011-09-20

文章信息/Info

Title:
Clinical application of adaptive support ventilation on patients with chronic obstructive pulmonary disease complicating respiratory failure
文章编号:
1672-271X(2011)05-0412-03
作者:
胡星星1; 周楚瑶2; 钟正江2; 申 红2; 孙 融2; 刘 青2
1.210000 江苏南京，南京大学医学院；2.210002 江苏南京，解放军81医院ICU
Author(s):
HU Xing-xing1; ZHOU Chu-yao2; ZHONG Zheng-jiang2; SHEN Hong2; SUN Rong2; LIU Qing2
1.Medical College of Nanjing University，Nanjing，Jiangsu 210000，China；2.ICU,81 Hospital of PLA，Nanjing，Jiangsu 210002，China
关键词:
适应性支持通气; 慢性阻塞性肺疾病; 呼吸衰竭; 内源性呼气末正压
Keywords:
ASV;  COPD;  respiratory failure;  PEEPi
分类号:
R563.9
DOI:
-
文献标志码:
A
摘要:
目的 比较适应性支持通气(ASV)和同步间歇指令通气(SIMV)对慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者内源性呼气末正压(PEEPi)和呼吸功的影响。 方法 30例有自主呼吸的COPD合并呼吸衰竭患者，在同样的设置下，先予以SIMV模式通气60 min，后改为ASV模式通气60 min，结束后再次回到SIMV模式通气60 min。记录上述三个60 min后的呼吸力学等参数。 结果 ASV模式下的平台压下降明显(P<0.01)；ASV模式PEEPi的发生率较SIMV模式明显下降(P<0.05)；器械附加功(WOBimP)和吸气压力时间乘积(PTP)均小于SIMV下的参数(P<0.01)。结论 在部分支持通气过程中，ASV相对于SIMV，能明显改善高通气力学状态，有利于降低呼吸负荷和呼吸做功。
Abstract:
Objective To analyse the influence of ASV and SIMV on PEEPi and WOBimP of respiratory failure patients with COPD. Methods Thirty patients with COPD complicating respiratory failure were collected and treated with partial mechanical ventilation,which initially in SIMV for 60 mins,then turned to ASV for 60 mins,and finally turned back to SIMV for 60 mins. The parameters of respiratory mechanics were recorded every 60 mins. Results PPLATE was obviously reduced in ASV mode(P<0.01); the occurring rate of PEEPi in ASV was less than that in SIMV mode(P<0.05).WOBimP and PTP in ASV mode were less than those in SIMV mode(P<0.01). Conclusion ASV mode can improve the status of respiratory mechanics in COPD patients with respiratory failure,and it can be in favor of reducing the load and work of respiratory.

参考文献/References:

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2011-09-20