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[1]陈芳芳,王国洪,李家亮,等.血清抑制素-A水平与异位妊娠的相关性研究[J].医学研究与战创伤救治(原医学研究生学报),2012,14(05):411-412.
　CHEN Fang-fang,WANG Guo-hong,LI Jia-liang,et al.A study on correlation between the serum levels of inhibin-A and the ectopic pregnancy[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2012,14(05):411-412.
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血清抑制素-A水平与异位妊娠的相关性研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第14卷
期数:
2012年05期
页码:
411-412
栏目:
出版日期:
2012-09-20

文章信息/Info

Title:
A study on correlation between the serum levels of inhibin-A and the ectopic pregnancy
文章编号:
1672-271X(2012)05-0411-02
作者:
陈芳芳; 王国洪; 李家亮; 李晓军
210002 江苏南京，南京军区南京总医院全军临床检验医学研究所
Author(s):
CHEN Fang-fang; WANG Guo-hong; LI Jia-liang; LI Xiao-jun
Department of Neurology,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China
关键词:
异位妊娠; 抑制素-A; β-人绒毛膜促性腺激素; 孕酮
Keywords:
ectopic pregnancy;  inhibin-A;  β-human chorionic gonadotropin;  progesterone
分类号:
R714.22
DOI:
-
文献标志码:
A
摘要:
目的 探讨异位妊娠患者血清中抑制素-A(INH-A)的水平变化及临床意义。方法 采用全自动化学发光免疫分析(CLIA)法对异位妊娠50例(观察组)，正常孕妇50例(对照组)血清中INH-A、β-人绒毛膜促性腺激素(β-HCG)及孕酮水平进行检测。结果 与对照组相比，观察组血清中INH-A(3.6±1.4)、β-HCG(308.5±57.9)、孕酮(29.8±9.4)的水平均明显降低，差异有统计学意义(P<0.01)。结论 血清INH-A对异位妊娠的早期诊断和治疗起到积极的辅助作用。
Abstract:
Objective To investigate the serum levels and clinical significance of INH-A in ectopic pregnancy by chemiluminescence immune assay (CLIA).Methods The serum levels of INH-A,β-HCG and Prog in 50 patients with ectopic pregnancy (the study group) and 50 normal pregnant women (the control group) were detected by CLIA.Results Compared with the control group,the serum levels of INH-A (3.6±1.4),β-HCG (308.5±57.9) and Prog (29.8±9.4) were significantly decressed,the difference was significant (P<0.01).Conclusion INH-A plays an important role in sustaining the normal early pregnancy,and predicts the early pregnancy outcome effectively.It plays an active supporting role in the early diagnosis and treatment of ectopic pregnancy.

参考文献/References:

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[3]杨丽梅,杨 冰,李桂香.血清β-HCG、孕酮在宫外孕诊断中的意义[J].中国妇幼保健,2009,24(10):1382-1383.
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[6]Cartwright J,Duncan WC,Critchley HO,et al.Serum biomarkers of tubalectopic pregnancy:current candidates and future possibilities[J].Reproduction,2009,138(1):9-22.
[7]Luisi S,Florio P,D'Antona D,et al.Maternal serum inhibin A levels are a marker of a viable trophoblast in incomplete and complete miscarriage[J].Eur J Endocrinol,2003,148(2):233-236.
[8]Florio P,Luisi S,Ciarmela P,et al.Inhibins and activins in pregnancy[J].Mol Cellular Endocrinol,2004,225(1-2):93-100.
[9]Muttukrishna S,Jauniaux E,Greenwold N,et al.Curculating levels of inhibin A and follistatin in missed and recurrent miscarriages[J].Hum Reprod,2002,17(12):3072-3078.
[10]Al-Azemi M,Ledger WL,Diejomaoh M,et al.Measurement of inhibin A and inhibin pro-alphaC in early human pregnancy and their role in the prediction of pregnancy outcome in patients with recurrent pregnancy loss[J].Fertil Steril,2003,80(6):1473-1479.
[11]Hauzman E,Fedorcsák P,Klinga K,et al.Use of serum inhibin A and human chorionic gonadotropin measurements to predict the outcome of in vitro fertilization pregnancies[J].Fertil Steril,2004,81(1):66-72.
[12]Seifer DB,Lambert-Messerlian GM,Canick JA,et al.Serum inhibin levels are lower in ectopic than intrauterine spontaneously conceived pregnancies[J].Fertil Steril,1996,65(3):667-669.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2012-09-20