|本期目录/Table of Contents|

[1]黎承军,流小舟 赵建宁,吴苏稼,等.Survivin基因与骨肉瘤关系的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2013,15(03):276-278.[doi:10.3969/j.issn.1672-271X.2013.03.022]
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Survivin基因与骨肉瘤关系的研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第15卷
期数:
2013年03期
页码:
276-278
栏目:
出版日期:
2013-03-30

文章信息/Info

Title:
-
作者:
黎承军; 流小舟 赵建宁; 吴苏稼; 施 鑫
210002 江苏南京,南京军区南京总医院骨科
Author(s):
-
关键词:
Survivin基因; 骨肉瘤; 治疗与预后
Keywords:
-
分类号:
R738.1
DOI:
10.3969/j.issn.1672-271X.2013.03.022
文献标志码:
A
摘要:
骨肉瘤的发生发展与细胞异常增殖和凋亡调节紊乱有着密切的关系,而作为凋亡抑制蛋白(IAP)家族新成员的Survivin是联系细胞周期和细胞凋亡界面的重要因子,其为骨肉瘤的靶向治疗提供了新的途径和良好的前景。
Abstract:
-

参考文献/References:

[1] 高 瞻.核素骨显像在肿瘤临床中的应用[J].东南国防医药,2009,12(6):523-526. [2] Smith BR,Stabile BE.Extreme aggressiveness and lethality of gastric adenocarcinoma in the very young[J].Arch Surg,2009,144(2):506–510. [3] Nedelcu T,Kubista B,Koller A,et al.Livin and Bcl-2 expression in high-grade osteosarcoma[J].Cancer Res Clin Oncol,2008,134(2):237-244. [4] Roshdy N,Mostafa T.Seminal plasma survivin in fertile and infertile males[J].J Uro1,2009,181(3):1269-1272. [5] 林 任,廖前德,吕红斌.Survivin蛋白在人骨肉瘤、骨软骨瘤和正常骨组织中表达的初步研究[J].中国现代医学杂志,2010,20(21):3263-3266. [6] Karam JA,Lotan Y,Ashfaq R,et al.Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder[J].Urology,2007,70(3):482-486. [7] Nikolovska-Coleska Z,Mengher JL,Liang S,et al.Interaction of a cyclic,bivalent smac mimetic with the x-linked inhibitor of poptosis protein[J].Biochemistry,2008,47(37):9811-9982. [8] Kappler M,Rot S,Taubert H,et al.The effects of knockdown ofwild-type surviving,survivin-2B or survivin-delta3 on the radiosensitization in a soft tissue sarcoma cells in vitro under different oxygen conditions[J].Cancer Gene Ther,2007,14(2):994-1001. [9] Tirado OM,Mateo-Lozano S,Notario V.Roscovitine is an effective inducer of apoptosis of Ewing sarcoma family tumor cells in vitro and in vivo[J].Cancer Res,2005,65(20):9320-9327. [10] Wolanin K,Piwocka K.Role of survivin in mitosis[J].Postepy Biochem,2007,53(1):10-18. [11] Knauer SK,Bier C,Habtemichael N,et al.The Survivin-crm1 interaction is essential for chromosomal passenger complex localization and function[J].EMBO Rep,2006,7(1):1259-1265. [12] O'Connor DS,Schechner JS,Adida C,et al.Control of apoptosis during angiogenesis by survivin expression in endothelial cells[J].Am Pathol,2000,156(2):393-398. [13] Tran J,MasterZ,Yu JL,et al.A role for survivin in chemoresistance of endothelial cellsmediated by VEGF[J].Proc NatlAcad SciUSA,2002,99(7):4349-4354. [14] Coma S,Noe V,Lavarino C,et al.Use of siRNAs and antisense oligonucleotides against survivin RNA to inhibit steps leading to tumor angiogenesis[J].Oligonucleotides,2004,14(2):100-113. [15] Zhang HZ,Wang Y,Gao P,et al.Silencing stathmin gene expression by survivin promoter-driven siRNA vector to reverse malignant phenotype of tumorcells[J].Cancer Biol Ther,2006,5(11):1457-1461. [16] Osaka E,Suzuki T,Osaka S,et al.Survivin expression levels as independent predictors of survival for osteosarcoma patients[J].J Orthop Res,2007,25(1):116-121. [17] Liang X,Da M,Zhuang Z,et al.Effects of Survivin on cell proliferation and apoptosis in MG-63 cells in vitro[J].Cell Biol Int,2009,33(1):119-124. [18] Wu YF,Liang XJ,Liu YY,et al.Antisense oligonucleotide targeting survivin inhibits growth by inducing apoptosis in human osteosarcoma cells MG-63[J].Neoplasm,2010,57(6):501-506. [19] AignerA.Gene silencing through RNA interference(RNAi)in vivo:strategies based on the direct application of siRNAs[J].J Biotech,2006,124(1):12-25. [20] 杨彤涛,李存孝,张 勇,等.靶向survivin的siRNA对骨肉瘤细胞MG63的抑制作用[J].中国肿瘤生物治疗杂志,2008,15(2):125-128. [21] 饶耀剑,刘慧娟,夏仁云.survivin反义寡核苷酸抑制骨肉瘤细胞增殖及增加化疗敏感性的作用[J].医学研究生学报,2006,19(2):132-135. [22] Zou J,Gan M,Mao N,et al.Sensitization of osteosarcoma cell line SaOS-2 to chemotheraphy by downregulating surviving [J].Arch Med Res,2010,41(3):162-169. [23] 易 磊,郭风劲,陈安民,等.低分子量肝素对骨肉瘤细胞增殖和survivin表达的影响[J].肿瘤学杂志,2007,13(4):277-279.

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备注/Memo

备注/Memo:
基金项目: 全军医药卫生科研基金攻关课题(06G020)
更新日期/Last Update: 2013-05-20