|本期目录/Table of Contents|

[1]许德兵,吴凌云综述,宋 勇审校.miRNA与肺癌关系的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2014,16(01):73-75,80.
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miRNA与肺癌关系的研究进展()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第16卷
期数:
2014年01期
页码:
73-75,80
栏目:
出版日期:
2014-02-20

文章信息/Info

Title:
-
作者:
许德兵1吴凌云2综述宋 勇3审校
1.210002江苏南京,南京军区南京总医院干部保健科;2.210002江苏南京,解放军81医院药剂科;3.210002 江苏南京,南京军区南京总医院呼吸内科
Author(s):
-
关键词:
肺癌miRNA诊断
Keywords:
-
分类号:
R605.97
DOI:
-
文献标志码:
A
摘要:
miRNA是一类长约21~25个核苷酸的小分子非编码RNA,能调节转录后靶基因的表达,它在机体内对生长发育、细胞繁殖、代谢、凋亡等生理过程发挥着重要作用。miRNA具有癌基因或抑癌基因的双重作用,其表达水平的变化与肿瘤形成密切相关。肺癌是危害人类健康的恶性肿瘤之一,由于常常不能及时诊断,大部分肺癌患者发现时多已经是晚期,因而预后较差。近年来,miRNA与肺癌的关系备受关注。
Abstract:
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参考文献/References:

[1] Sterlacci W,Fiegl M,Tzankov A.Prognostic and predictive value of cell cycle deregulation in non-small-cell lung cancer[J].Pathobiology,2012,79(4):175-194.
[2] 陈一天,徐益琛,黄桂春,等.转移相关基因1蛋白在非小细胞肺癌组织中的表达及与预后的相关性[J].医学研究生学报,2013,26(7):717-720.
[3] Berezikov E,Guryev V,Vande Belt J,et al.Phylgdenetic shadowing and computational identification of human microRNA genes[J].Cell,2005,120(1):21-24.
[4] Williams AE.Functional aspects of animal microRNAs[J].Cell Mol Life Sci,2008,65(4):545-562.
[5] 周亚星,吴文溪.miRNA调控树突状细胞成熟机制研究进展[J].医学综述,2013,19(1):34-37.
[6] 钱 莘,丁金勇,敖绪军,等.小鼠支气管肺泡干细胞miRNAs表达谱的鉴定[J].肿瘤学杂志,2011,17(9):657-661.
[7] Cho WC.Updates in cancer research:insights from the AACR 100th AnnualMeeting[J].Expert Rev Mol Diagn,2009,9(5),411-416.
[8] Seike M,Goto A,Okano T,et al.MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers[J].Proc Natl Acad Sci USA,2009,106(29):12085-12090.
[9] 印 洁,李玉枫,宋 勇,等.miR-21在肺癌血管生成中的作用及培美曲塞对其影响[J].医学研究生学报,2012,25(5):476-480.
[10] 王 璇,时姗姗,马恒辉.非小细胞肺癌表皮生长因子受体基因突变的结果分析[J].东南国防医药,2012,14(5):387-389.
[11] 任为正,叶鸿飞,赵 健,等.MicroRNA let-7与肺癌关系的研究进展[J].中国肿瘤生物治疗杂志,2009,16(4):418-421.
[12] 王 鹤,刘志利,德 伟,等.microRNA-335 对人非小细胞肺癌细胞迁移、侵袭及增殖能力的影响[J].南京医科大学学报:自然科学版,2012,32(6):795-799.
[13] Vickers MM,Bar J,Gorn-Hondermann I,et al.Stage-dependent differential expression of microRNAs in colorectal cancer:potential role as markers of metastatic disease[J].Clin Exp Metastasis,2012,29(2):123-132.
[14] Shu M,Zheng X,Wu S,et al.Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells[J].Mol Cancer,2011,10:59.
[15] Xu Y,Zhao F,Wang Z,et al.MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-wand specificity protein 1 [J].Oncogene,2012,31(11):1398-1407.
[16] 曾 婷,郝 丽,谢逸欣,等.microRNA-34a与非小细胞肺癌的关系及其可能调节机制[J].中国医药导报,2012,9(23):5-7.
[17] Wang R,Wang ZX,Yang JS,et al.MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14(RAB14)[J].Oncogene,2011,30(23):2644-2658.
[18] Lu J,Getz G,Miska EA,et al.MicroRNA expression profiles classify human cancels[J].Nature,2005,435(7043):834-838.
[19] 王 生,王启鸣,王慧娟,等.microRNA-31在原发性肺癌组织中的表达及临床意义[J].肿瘤防治研究,2012,39(3):281-284.
[20] 李光剑,黄云超,何越峰,等.miRNA标志物在诊断云南省宣威地区早期非吸烟女性肺癌中的价值[J].肿瘤防治研究,2012,39(7):802-806.
[21] Lebanony D,Benjamin H,Gilad S,et al.Diagnostic assay based on hsamiR-205 expression distinguishes squamous from nonsquamous non-smallcell lung carcinoma[J].J Clin Oncol,2009,27(12):2030-2037.
[22] Barshack I,Lithwick-Yanai G,Afek A,et al.MicroRNA expression differentiates between primary lung tumors and metastases to the lung[J].Pathol Res Pract,2010,206(8):578-584.
[23] Bianchi F,Nicassio F,Marzi M,et al.A serum circulating microRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer[J].EMBO Molecular Medicine,2011,3(8):495-503.
[24] Chen X,Ba Y,Ma L,et al.Characterization of microRNAs in serum:a novel class of biomarkers for diagnosis of cancer and other diseases[J].Cell Res,2008,18(10):997-1006.
[25] Rabinowits G,Gercel-Taylor C,Day JM,et al.Exosomal microRNA:a diagnostic marker for lung cancer[J].Clin Lung Cancer,2009,10(1):42-46.
[26] Wei J,Gao W,Zhu CJ,et al.Identification of plasma microRNA-213 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer[J].Chin J Cancer,2011,30(6):407.
[27] 杨小倩,张义宏,孙 波,等.痰液MicroRNAs 检测在非小细胞肺癌诊断中的应用价值[J].临床肺科杂志,2013,18(2):226-229.
[28]Kumar MS,Erkeland SJ,Pester RE,et al.Suppression of non-small cell lung tumor development by the let-7 microRNA family[J].Proc Natl Acad Sci USA,2008,105(10):3903-3908.
[29]Liu X,Sempere LF,Galimberti F,et al.Uncovering growth-suppressive microRNAs in lung cancer[J].Clin Cancer Res,2009,15(4):1177-1183.
[30] Hu Z,Chen X,Zhao Y,et al.Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer[J].J Clin Oncol,2010,28(10):1721-1725.
[31] Rao E,Jiang C,Ji M,et al.The miRNA-17~92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation[J].Leukemia,2012,26(5):1064-1072.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2014-01-20