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[1]陈贤明,黄少华,杨 帆,等.影响鼻咽癌预后的相关因素分析[J].医学研究与战创伤救治(原医学研究生学报),2014,16(06):584-586，604.[doi:10.3969/j.issn.1672-271X.2014.06.008]
　CHEN Xian-ming,HUANG Shao-hua,YANG Fan,et al.Analysis of factors related to the NPC patients prognosis[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2014,16(06):584-586，604.[doi:10.3969/j.issn.1672-271X.2014.06.008]
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影响鼻咽癌预后的相关因素分析()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第16卷
期数:
2014年06期
页码:
584-586，604
栏目:
出版日期:
2014-11-20

文章信息/Info

Title:
Analysis of factors related to the NPC patients prognosis
作者:
陈贤明; 黄少华; 杨 帆; 王茂鑫
350025 福建福州，南京军区福州总医院耳鼻咽喉头颈外科
Author(s):
CHEN Xian-ming; HUANG Shao-hua; YANG Fan; WANG Mao-xin.
Department Of Otolaryngology Head and Neck Surgery，Fuzhou General Hospital of Nanjing Military Command,PLA，Fuzhou,Fujian 350025,China
关键词:
鼻咽癌;  临床表现;  预后
Keywords:
nasopharyngeal carcinoma(NPC);  clinical manifestations;  prognosis
分类号:
R739.6
DOI:
10.3969/j.issn.1672-271X.2014.06.008
文献标志码:
A
摘要:
目的 回顾性分析鼻咽癌患者临床资料，探讨影响鼻咽癌预后的相关因素。方法 总结2006年1月1日-2012年9月1日就诊于南京军区福州总医院的1286例鼻咽癌患者的病理 类型、血清EBV-IgA检测结果、年龄、性别、T分期、N分期、治疗方式、复发、远处转移等临床资料，并随访其生存率。用Kaplan-Meier法进行生存分析，Log-Rank法检验组间生存 率差异。Cox回归模型进行多因素分析。结果 单因素分析结果显示，T分期、N分期、临床分期是影响鼻咽癌的预后因素(P＜0.05)，而性别、病理类型、血清EBV-IgA阳性、治疗方 式等对预后无明显影响(P＞0.05)。多因素分析结果显示，年龄、T分期、N分期、治疗方式是影响鼻咽癌预后的独立危险因素(P＜0.05)。结论 年龄、T分期、N分期、治疗方式是影 响鼻咽癌预后的独立危险因素。T分期、N分期、临床分期越晚，预后越差，综合治疗比单纯放疗预后好，性别、病理类型、血清EBV-IgA阳性对鼻咽癌预后无明显影响。
Abstract:
Objective To investigate the factors related to the NPC patients prognosis.Methods Clinical data of 1286 NPC patients received treatment in Fuzhou General Hospital of Nanjing Military Command from Jan 1,2006 to Sep 1,2012 were studied retrospectively.The data included pathological types,results of serum EBV-IgA,age,T stage,N stage,treatment methods,recurrence and metastasis,and the patients survival condition.Kaplan-Meier was used to survival analysis and Log-Rank was used to test the difference of survival rate among the study groups respectively.In addition,Cox regression mode was used for multiple factors analysis.Results Single factor analysis showed that T stage,N stage and clinical stage were statistical difference in the influence on prognosis(P＜0.05),while the gender,pathological types and positive rate of serum EBV-IgA were not(P＞0.05).Multiple factor analysis exhibited that the age,T stage,N stage,clinic stage and treatment methods were statistical different in the influence on prognosis(P＜0.05).Conclusion It was found that the age,T stage,N stage,treatment were significant correlation with the prognosis of nasopharyngeal carcinoma by multivariate study.The later the T,N stage were,clinical stage,the worse the prognosis were.The comprehensive treatment is better than radiotherapy alone.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2014-11-20