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[1]张 康,高 翔,李文平,等.大骨瓣减压与常规骨瓣减压治疗重型颅脑损伤的对照研究[J].医学研究与战创伤救治(原医学研究生学报),2015,17(03):256-258.[doi:10.3969/j.issn.1672-271X.2015.03.010]
　ZHANG Kang,GAO Xiang,LI Wen-ping,et al.Large bone flap decompression with conventional bone disc decompression treatment of severe craniocerebral injury clinical control study[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(03):256-258.[doi:10.3969/j.issn.1672-271X.2015.03.010]
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大骨瓣减压与常规骨瓣减压治疗重型颅脑损伤的对照研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年03期
页码:
256-258
栏目:
出版日期:
2015-05-20

文章信息/Info

Title:
Large bone flap decompression with conventional bone disc decompression treatment of severe craniocerebral injury clinical control study
作者:
张 康; 高 翔; 李文平; 薛彦平
212001 江苏镇江，解放军359医院神经外科
Author(s):
ZHANG Kang;  GAO Xiang;  LI Wen-ping;  XUE Yan-ping.
Department of Neurosurgery， 359 Hospital of PLA， Zhenjiang， Jiangsu 212001， China
关键词:
标准大骨瓣减压; 常规骨瓣减压; 重型颅脑损伤
Keywords:
standard big bone flap decompression;  conventional bone disc decompression;  severe craniocerebral injury
分类号:
R651.15
DOI:
10.3969/j.issn.1672-271X.2015.03.010
文献标志码:
A
摘要:
目的 探讨大骨瓣减压与常规骨瓣减压治疗重型颅脑损伤的临床效果。方法 随机将重型颅脑损伤136例分两组，每组68例。观察组采用标准大骨瓣减压治疗，对照组采用常规骨瓣减压治疗。比较两组临床疗效，治疗前后神经功能缺损评分和格拉斯哥预后分级评分（GOS），观察术前和术后第1、3、7 天颅内压变化情况。结果 ①观察组良好率（51.47%）显著高于对照组（19.12%），差异有统计学意义(P＜0.05)；②两组术前颅内压比较差异无统计学意义(P＞0.05)，两组术后第1、3、7 天颅内压较术前显著降低(P＜0.05)，且观察组颅内压降低幅度优于对照组(P＜0.05)；③治疗后，观察组患者神经功能缺损评分、GOS 改善程度、并发症发生率显著优于对照组(均P＜0.05)。结论 采用大骨瓣减压治疗重型颅脑损伤，能够明显降低术后颅内压，显著改善患者预后效果，值得在临床中推广应用。
Abstract:
Objective To study the big bone flap decompression with conventional bone disc decompression for treatment of severe head injury. Methods 136 cases of severe craniocerebral injury patients were randomly divided into two groups， 68 cases in each group. Observation group with a standard big bone flap subjected to decompression therapy and the control group B with normal bone disc subjected to decompression therapy. Compare two groups of clinical curative effect， neural function defect scale before and after the treatment and prognosis of Glasgow grading scores， observe the preoperative and postoperative intracranial pressure changes in 1， 3， 7 days. Results ①The cure rate of observation group (51.47%) was significantly higher than that of control group (19.12%) (P<0.05); ②The preoperative intracranial pressure between the two groups had no statistical significance (P>0.05)， two groups of postoperative intracranial pressure 1， 3， 7 days a preoperative decreased significantly (P<0.05)， intracranial pressure reduction due to the control group and observation group (P<0.05); ③After treatment， the observation group of patients with nerve function defect score， GOS score improvement degree， complication incidence was significantly better than that of control group (all P<0.05). Conclusion The big bone flap decompression treatment of severe head injury， can significantly reduce postoperative intracranial pressure， the prognosis of patients with significant improvement effect， is worth popularizing in clinical application.

参考文献/References:

[1]Lesko MM，Jenks T，O’Brien SJ，et al.Comparing model performance for survival prediction using total Glasgow Coma Scale and its components in traumatic brain injury[J]．J Neurotrauma，2013，30(1)：17-22．
[2]Lavinio A，Menon DK．Intracranial pressure：why we monitor it，how to monitor it，what to do with the number and what’s the future[J]．Curr Opin Anaesthesiol，2011，24(2)：117-123．
[3]谢 隽，标准大骨瓣减压与常规骨瓣减压术治疗重型颅脑损伤对比观察[J]．山东医药，2011，51(18)：107-108．
[4]樊欣鑫，李宇龙，万 兴．神经干细胞移植治疗颅脑损伤后神经功能缺失的研究进展[J]．现代医学，2013，41(4)：274-278．
[5]高 亮．正确评价颅内压监测在重型创伤性颅脑损伤救治中的地位[J]．中华创伤杂志，2013，29(2)：100-102．
[6]王 康，孙晓川，刘 科．重型颅脑损伤颅内压监测临床研究进展[J]．创伤外科杂志，2014，16(4)：370-372．
[7]王 宇，李锦平，杨新乾．标准大骨瓣减压治疗恶性大脑中动脉梗塞的疗效分析[J]．中国医药导刊，2013，15(3)：373-374．
[8]张建忠，龙连圣，辛志平．中重型颅脑损伤并发脑梗死的危险因素分析[J]．东南国防医药，2013，15(3)：234-237．
[9]叶 青．标准去骨瓣减压与常规去骨瓣减压治疗重型颅脑外伤的对比研究[J]．实用心脑肺血管病杂志，2012，20(2)：339-340．
[10]杨 磊．标准大骨瓣开颅减压术治疗重型颅脑损伤疗效分析[J]．河北医药，2010，32(8)：948-949.
[11]谭永康，许晓波，施小龙，等．标准大骨瓣开颅减压术在治疗重型颅脑外伤并发脑疝中的应用[J]．立体定向和功能性神经外科杂志，2011，24(2)：114-116.

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更新日期/Last Update: 2015-05-20