[1]汤学勤,张艳峰,赵红梅,等.高龄2型糖尿病合并缺血性脑血管病患者的临床特征分析[J].医学研究与战创伤救治(原医学研究生学报),2015,17(05):499-501.[doi:10.3969/j.issn.1672-271X.2015.05.016]
　TANG Xue-qin,ZHANG Yan-feng,ZHAO Hong-mei,et al.Analysis of the clinical characteristics of elderly type 2 diabetes mellitus patients with ischemic cerebrovascular disease[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2015,17(05):499-501.[doi:10.3969/j.issn.1672-271X.2015.05.016]
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高龄2型糖尿病合并缺血性脑血管病患者的临床特征分析()

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第17卷
期数:
2015年05期
页码:
499-501
栏目:
出版日期:
2015-09-30

文章信息/Info

Title:
Analysis of the clinical characteristics of elderly type 2 diabetes mellitus patients with ischemic cerebrovascular disease
作者:
汤学勤1; 张艳峰1; 赵红梅1; 梁春海1; 郝雅娟1; 黄先涛2
1.075000 河北张家口，张家口市第五医院内科；2.075000 河北张家口，河北北方学院附属第一医院医务部
Author(s):
TANG Xue-qin1;  ZHANG Yan-feng1;  ZHAO Hong-mei1;  LIANG Chun-hai1;  HAO Ya-juan1;  HUANG Xian-tao2.
1.The Fifth Hospital of Zhangjiakou City， Zhangjiakou ， Hebei 075000， China； 2.The First Affiliated Hospital of Hebei North University， Zhangjiakou， Hebei 075000， China
关键词:
缺血性脑血管病; 2型糖尿病; 临床特征; 高龄患者
Keywords:
ischemic cerebrovascular disease;  type 2 diabetes;  clinical characteristics;  elderly patients
分类号:
R587.1；R743.3
DOI:
10.3969/j.issn.1672-271X.2015.05.016
文献标志码:
A
摘要:
目的 探讨高龄2型糖尿病合并缺血性脑血管病患者的临床特征。方法 选取某院2013年1月-2014年1月高龄2型糖尿病合并缺血性脑血管病患者50例为观察组，同期单 纯缺血性脑血管高龄患者50例为对照组，检测两组的各项血脂水平，观察组予以胰岛素、适当运动及合理控制饮食控制血糖后，两组均予以阿司匹林与奥扎格雷钠治疗，两组均治 疗2周，比较两组的各项血生化指标水平及临床有效率、神经功能缺损程度。结果 观察组的尿酸（UA）、纤维蛋白原（FIB）、三酰甘油（TG）、血胆固醇（TC）水平显著高于对 照组（P<0.05），而高密度脂蛋白（HDL）显著低于对照组(P<0.05)；观察组、对照组的临床有效率分别为88.0%、58.0%，差异具有统计学意义（P<0.05）；两组治疗后的神经功能 缺损评分情况均有显著改善，对照组神经功能缺损的评分显著优于观察组（P<0.05）。结论 2型糖尿病合并缺血性脑血管病患者常合并FIB、UA及血脂代谢异常，治疗效果较差， 应积极控制血糖、血脂水平。
Abstract:
Objective To investigate the clinical characteristics of elderly type 2 diabetes mellitus patients with ischemic cerebrovascular disease. Methods Selected 50 cases of elderly type 2 diabetic patients with ischemic cerebral vascular disease as the observation group in our hospital from January 2013 to January 2014， the 50 cases of patients with selected purely ischemic cerebral vascular as control group. The level of blood lipid indexes were detected in two groups. The observation group were treated with insulin， proper exercise and reasonable diet to control blood glucose. Two groups were treated with aspirin and sodium ozagrel for 2 weeks. Compare blood biochemical indexes， clinical comparison of efficiency and degree of nervous functional defect in two groups. Result Uric acid (UA)， fibrinogen (FIB)， triglyceride (TG)， serum cholesterol (TC) levels of the observation group were significantly higher than that in the control group (P<0.05). High density lipoprotein (HDL) were significantly lower than that of control group (P<0.05). The effective rate of the observation group and the control group were 88.0%， 58.0% respectively with difference statistically significant (P<0.05). After treatment， theneural function of the two groups defect score were significantly improved， of nerve function defect score in the observation group was significantly lower than that in the control group (P<0.05). Conclusion Type 2 diabetes mellitus complicated with ischemic cerebral vascular disease patients often associated with FIB， UA and dyslipidemia and the treatment result is bad. It should actively control blood sugar， blood lipid level.

参考文献/References:

[1]朱廷彦，崔延东.急性脑血管病合并2型糖尿病106例临床分析[J].中国实用医刊，2010，37(12)：437-438.
[2]卢舜飞，朱满莲.老年2型糖尿病合并脑梗死的相关危险因素分析[J].中国现代医生，2013，51(31)：1256-1258.
[3]杜大勇，许 航，张红梅，等.缺血性脑血管病合并2型糖尿病患者全脑血管造影特点分析[J].中风与神经疾病杂志，2014，31(1)：61-63.
[4]刘婕好，王丽娟，刘 煜.2型糖尿病合并心脑血管病变202例相关危险因素评价[J].中国老年学杂志，2012，32(6)：332-333.
[5]袁 远，徐 燕，高旭光.匹伐他汀与阿托伐他汀对缺血性脑卒中患者血脂调控的临床对比研究[J].中华老年心脑血管病杂志，2013，15(10)：1024-1026.
[6]张丽敏，王庆开，叶苗苗，等.2型糖尿病炎症因子水平与心脑血管病变的相关性[J].中国老年学杂志，2013，33(5)：1256-1258.
[7]裘丽红，李武艳，李晓娜，等.2型糖尿病合并急性缺血性脑血管病患者颈动脉斑块稳定性及相关因素分析[J].中国实用神经疾病杂志，2013，16(8)：27-29.
[8]丁 琼.2型糖尿病合并脑梗死患者60例血脂水平及预后分析[J].中国老年学杂志，2011，31(17)：1256-1258.
[9]畅 坚，蔡艺灵，张 磊，等.糖尿病和非糖尿病缺血性脑血管病患者血管病变的分布特征[J].中国脑血管病杂志，2010，8(6)：303-307.
[10]赵言兵，刘友娟.2型糖尿病合并脑血管病98例临床分析[J].中国实用医刊，2014，33(11)：240-242.
[11]Wei WQ，Leibson CL，Ransom JE.et al.The absence of longitudinal data limits the accuracy of high-throughput clinical phenotyping for identifying type 2 diabetes mellitus subjects[J].Int J Med Inform，2013，82(4)：239-247.
[12]Zhu C，Liang QL，Hu P，et al.Phospholipidomic identification of potential plasma biomarkers associated with type 2 diabetes mellitus and diabetic nephropathy[J].Talanta，2011，85(4)：1711-1720.
[13]Sertoglu E，Kurt I，Tapan S，et al.Comparison of plasma and erythrocyte membrane fatty acid compositions in patients with end-stage renal disease and type 2 diabetes mellitus[J].Chem Phys Lipids，2014，178：11-17.

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备注/Memo

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更新日期/Last Update: 2015-09-20