|本期目录/Table of Contents|

[1]段洪波,田雯艳,张金彪.429例高血压患者眼底改变的发生率及影响因素[J].医学研究与战创伤救治(原医学研究生学报),2016,18(04):402-404,418.[doi:10.3969/j.issn.1672-271X.2016.04.020]
 DUAN Hong-bo,TIAN Wen-yan,ZHANG Jin-biao..Incidence rate of retinal changes among patients with hypertension and its influencing factors in Cangzhou City[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2016,18(04):402-404,418.[doi:10.3969/j.issn.1672-271X.2016.04.020]
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429例高血压患者眼底改变的发生率及影响因素()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第18卷
期数:
2016年04期
页码:
402-404,418
栏目:
出版日期:
2016-08-20

文章信息/Info

Title:
Incidence rate of retinal changes among patients with hypertension and its influencing factors in Cangzhou City
作者:
段洪波田雯艳张金彪
061001河北沧州,沧州中西医结合医院神经内科
Author(s):
DUAN Hong-boTIAN Wen-yanZHANG Jin-biao.
Department of Neurology, Integrative Medicine Hospital of Cangzhou,Cangzhou,Hebei 061001,China
关键词:
高血压眼底改变影响因素
Keywords:
high blood pressure retinal changes factors
分类号:
R544
DOI:
10.3969/j.issn.1672-271X.2016.04.020
文献标志码:
A
摘要:
目的 探讨沧州市高血压患者眼底改变的发生情况及相关影响因素,为高血压性眼底病变的防治提供依据。方法 随机选取沧州市429例高血压患者为研究对象,其中无眼底病变患者131例为对 照组,并发眼底改变患者298例为实验组,实验组患者根据眼底病变情况分为Ⅰ、Ⅱ、Ⅲ、Ⅳ级,分别检测各组患者的血压、甘油三酯(TG)、总胆固醇(TC)、同型半胱氨酸(Hcy)以及蛋白尿,并与 眼底病变的严重程度进行相关性分析。结果 沧州市429例高血压患者眼底病变的发生率为69.46%,与对照组相比,发生眼底病变的高血压患者收缩压较高,血清中TC和Hcy水平较高,尿液中蛋白的检出 率较高,差异均有统计学意义(P<0.05)。Pearson相关分析显示,收缩压、TC、Hcy和蛋白尿水平与高血压患者眼底病变分级呈正相关(P<0.05)。结论 本研究中沧州市高血压患者眼底改变的发生率 达69.46%,其病变严重程度与患者收缩压、TC、Hcy和蛋白尿相关。
Abstract:
Objective To investigate the incidence and related factors in patients with hypertension retinal changes in Cangzhou City, in order to provide the basis for prevention and treatment of disease. Methods 429 cases were randomly selected for the study in patients with hypertension in Cangzhou City, including 131 patients without retinopathy as the control group, 298 cases complicated with retinal changes in patients as the experimental group. The experimental group were divided according to the fundus lesions Ⅰ, Ⅱ, Ⅲ, Ⅳ grade. Patients in each group were measured with blood pressure, triglyceride (TG), total cholesterol (TC), homocysteine (Hcy) and proteinuria, and performed with the severity of retinopathy correlation analysis. Results Incidence rate of patients Cangzhou City with hypertension retinopathy was 69.46%. Compared with the control group, patients with hypertension retinopathy had higher systolic blood pressure, higher serum TC and Hcy levels, urine protein detection rate, and differences were statistically significant (P<0.05). Pearson correlation analysis showed that systolic blood pressure, TC, Hcy and proteinuria in hypertensive patients with retinopathy grade were positively correlated (P<0.05). Conclusion Incidence of fundus changes in patients with hypertension of Cangzhou city is 69.46%, and its severity is associated with the systolic pressure, TC, Hcy and proteinuria.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2016-07-20