|本期目录/Table of Contents|

[1]季春燕.派特灵治疗宫颈持续人乳头瘤病毒感染的临床研究[J].医学研究与战创伤救治(原医学研究生学报),2017,19(05):492-495.[doi:10.3969/j.issn.1672-271X.2017.05.011]
　JI Chun-yan.The clinical observation of Paiteling on treatment of cervical HPV infection[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2017,19(05):492-495.[doi:10.3969/j.issn.1672-271X.2017.05.011]
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派特灵治疗宫颈持续人乳头瘤病毒感染的临床研究()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第19卷
期数:
2017年05期
页码:
492-495
栏目:
出版日期:
2017-09-29

文章信息/Info

Title:
The clinical observation of Paiteling on treatment of cervical HPV infection
作者:
季春燕
作者单位：212001镇江，江苏大学附属医院妇科
Author(s):
JI Chun-yan
(Department of Gynecology，Affiliated Hospital of Jiangsu University, Zhenjiang 212001，Jiangsu, China)
关键词:
人乳头瘤病毒; 派特灵; 疗效
Keywords:
Human papilloma virus;  Paiteling;  Clinical effect
分类号:
R737.33
DOI:
10.3969/j.issn.1672-271X.2017.05.011
文献标志码:
A
摘要:
目的 研究派特灵治疗宫颈人乳头瘤病毒（HPV）感染的疗效。方法 回顾性分析2015年1月至2016年12月在镇江派特生物技术应用指导中心治疗的100例宫颈HPV持续感染患者资料，根据治疗后3个月和6个月复查结果 ，分为慢性炎/宫颈上皮内瘤变（CIN）Ⅰ组56例、CINⅡ-Ⅲ组15例、全子宫切除术后组8例和尖锐湿疣组21例，探讨派特灵治疗HPV感染的疗效及安全性。结果 治疗后3个月复查，73例治愈，治愈率为73%；治疗后6个月复查，86例治愈，治愈率为86%，另有8例好转，治疗有效率为94%。其中，全子宫切除术后组治疗有效率（87.50%）低于慢性炎/CINⅠ组（92.86%）、CINⅡ-Ⅲ组（93.33%）和尖锐湿疣组（100.00%），差异有统计学意义（P＜0.05）。结论 派特灵能有效抑制和清除HPV病毒，缩短HPV感染持续时间，对宫颈病变术后HPV持续感染亦有良好的疗效，对尖锐湿疣治疗效果明显。
Abstract:
Objective To evaluate the treatment efficacy of Paiteling on cervical human papilloma virus infection.Methods A retrospective analysis of 100 patients with persistent cervical HPV infection get TCT and HPV test 3 months and 6 months after Paiteling treatment in Paiteling Center between Jan.2015 and Dec.2016. 100 patients were divided into chronic inflammation/CINⅠgroup (56 cases), CINⅡ-Ⅲ group (15 cases)，post-hysterectomy group (8 cases) and condyloma acuminatum group (21 cases).Results 3 months after the treatment, 73 cases (73%) turned to HPV negative; 6 months after treatment, 84 cases (84%) turned to HPV negative, and another 8 cases of mixed improved with an effective rate of 94%. The effective rate was lower in post-hysterectomy group （87.50%） than chronic inflammation/CINⅠgroup （92.86%）, CINⅡ-Ⅲ group （93.33%） and condyloma acuminatum group （100.00%），and there was statistically significant difference (P<0.05).Conclusion Paiteling can effectively inhibit and remove HPV virus, shorten the duration, and also has good curative effect on persistent HPV infection of cervical lesions after surgery as well as obvious therapeutic effect on condyloma acuminatum.

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2017-09-20