|本期目录/Table of Contents|

[1]王文涛,陈贤明,郭文玲.血脂及凝血功能与突发性耳聋的相关性研究[J].医学研究与战创伤救治(原医学研究生学报),2018,20(02):138-141.[doi:10.3969/j.issn.1672-271X.2018.02.007]
 WANG Wen-tao,CHEN Xian-ming,GUO Wen-ling.The research of the correlation between blood lipid with coagulation function and sudden deafness[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2018,20(02):138-141.[doi:10.3969/j.issn.1672-271X.2018.02.007]
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血脂及凝血功能与突发性耳聋的相关性研究()

《医学研究与战创伤救治》(原医学研究生学报)[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年02期
页码:
138-141
栏目:
出版日期:
2018-03-20

文章信息/Info

Title:
The research of the correlation between blood lipid with coagulation function and sudden deafness
作者:
王文涛陈贤明郭文玲
作者单位:350025福州,南京军区福州总医院耳鼻咽喉头颈外科(王文涛、陈贤明、郭文玲)
Author(s):
WANG Wen-taoCHEN Xian-mingGUO Wen-ling
(Department Of Otolaryngology Head and Neck Surgery,Fuzhou General Hospital of Nanjing Military Region,PLA,Fuzhou 350025, Fujian, China)
关键词:
血脂凝血功能突发性耳聋
Keywords:
blood lipid coagulation function sudden deafness
分类号:
R764.43
DOI:
10.3969/j.issn.1672-271X.2018.02.007
文献标志码:
A
摘要:
目的 研究血脂及凝血功能与突发性耳聋的相关性。方法 选取南京军区福州总医院耳鼻咽喉头颈外科2015年9月至2016年12月的突发性耳聋住院患者201例作为突聋组,选取同时期住院的非耳聋患者201例作为对照组,比较治疗前2组患者血脂[三酰甘油(TG)、胆固醇(TC)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、脂蛋白a(LP-a)]和凝血指标[活化部分凝血酶时间(APTT)、凝血酶原时间(PT)、平均血小板体积(MPV)、纤维蛋白原(Fg)、血小板计数(PLT)],并对突聋组血脂和凝血指标与不同突发性耳聋类型进行相关性分析。结果 血脂指标:突聋组与对照组TG、TC、HDL-C、LDL-C差异具有统计学意义(P<0.05),而LP-a在2组之间差异无统计学意义(P>0.05);凝血指标:2组APTT、MPV差异具有统计学意义(P<0.05),而PT、Fg、PLT在2组中差异无统计学意义(P>0.05)。APTT与不同突聋类型患者均存在显著性相关性(rs=-0.165,P<0.05)。结论 血脂指标TC、TG、HDL-C、LDL-C及凝血指标APTT、MPV异常为突发性耳聋重要发病因素。凝血功能异常与不同听力类型突发性聋患者均相关。
Abstract:
Objective To research the correlation of blood lipid and coagulation function with the pathogenic risk factors of Sudden deafness.Methods 201 cases of sudden deafness that were in department of ENT in Fuzhou general hospital were collected from September 2015 to December 2016 as sudden deafness group. In the same period, 201 cases diagnosed as non-deafness were set as control group. The blood lipid (TG, TC, HDL-C, LDL-C, LP-a) and blood coagulation (APTT, PT, MPV, Fg, PLT) of two groups were compared.Results The difference of the TG, TC, HDL-C and LDL-C between study group and control group existed statistical significance (P<0.05). The difference of the lipoprotein had no statistical significance between study group and control group (P>0.05). The difference of the APTT and the MPV between two groups existed statistical significance (P<0.05). The difference of the PT, Fg and PLT between two groups did not exist statistical significance (P>0.05). APTT correlated with different types of sudden deafness in study group (rs=-0.165, P<0.05).Conclusion Blood lipid parameter TG,TC,HDL-C,LDL-C and coagulation function

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备注/Memo

备注/Memo:
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更新日期/Last Update: 2018-03-20