|本期目录/Table of Contents|

[1]吴健,王晶晶综述,杨鲸蓉,等.组蛋白去乙酰化酶抑制剂对食管癌细胞抗肿瘤活性及其相关机制的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2018,20(04):394-398.[doi:10.3969/j.issn.1672-271X.2018.04.015]
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组蛋白去乙酰化酶抑制剂对食管癌细胞抗肿瘤活性及其相关机制的研究进展()
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《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年04期
页码:
394-398
栏目:
综述
出版日期:
2018-07-20

文章信息/Info

Title:
-
作者:
吴健; 王晶晶综述; 杨鲸蓉; 曾志勇审校
作者单位：350025福州，福建医科大学福总临床学院(吴健、王晶晶）；350025福州，福州总医院心胸外科（杨鲸蓉、曾志勇）
Author(s):
-
关键词:
组蛋白去乙酰化酶; 组蛋白去乙酰化酶抑制剂; 食管癌; 肿瘤
Keywords:
-
分类号:
R966
DOI:
10.3969/j.issn.1672-271X.2018.04.015
文献标志码:
A
摘要:
食管癌是威胁人类身体健康的严重疾病之一，传统抗肿瘤药物因选择性差易引起较严重的不良反应。随着近年来临床医学研究水平的不断提高，有关肿瘤致病与发病机制的相关基本过程也逐渐被阐明，新型的抗肿瘤药物组蛋白去乙酰化酶(HDAC)抑制剂在临床中广泛应用开来。HDAC抑制剂能够作用于患者的肿瘤细胞，使肿瘤细胞的增殖受抑制，诱导肿瘤细胞凋亡，具有非常高的临床应用价值。HDAC抑制剂已经在血液／淋巴系统肿瘤治疗方面取得了一定成果，而HDAC抑制剂在食管癌治疗方面的潜力正在被挖掘。HDAC抑制剂能够抑制食管癌细胞生长并诱导
Abstract:
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备注/Memo

备注/Memo:
基金项目：福建省自然科学基金（2017J01223）
更新日期/Last Update: 2018-07-20