|本期目录/Table of Contents|

[1]曾小娟,杨帆综述,黄惠娟审校.PM2.5对绝经后骨质疏松症的影响研究进展[J].医学研究与战创伤救治(原医学研究生学报),2018,20(05):523-526.[doi:10.3969/j.issn.1672-271X.2018.05.017]
点击复制

PM2.5对绝经后骨质疏松症的影响研究进展()
分享到62.8K

《医学研究与战创伤救治》（原医学研究生学报）[ISSN:1672-271X/CN:32-1713/R]

卷:
第20卷
期数:
2018年05期
页码:
523-526
栏目:
综述
出版日期:
2018-09-18

文章信息/Info

Title:
-
作者:
曾小娟; 杨帆综述; 黄惠娟审校
作者单位：350025福州，南京军区福州总医院妇产科（曾小娟、杨帆、黄惠娟）
Author(s):
-
关键词:
PM2.5; 绝经后骨质疏松症; 炎症机制; 脂肪代谢机制
Keywords:
-
分类号:
R711
DOI:
10.3969/j.issn.1672-271X.2018.05.017
文献标志码:
A
摘要:
绝经后骨质疏松症（PMOP）是中老年女性常见的疾病之一。主要发生在绝经后妇女，因雌激素缺乏导致骨量减少及骨组织结构变化，使骨脆性增加而易于骨折，以及由骨折引起的骨骼变形、疼痛、出现合并症，乃至死亡等问题，是骨质疏松中最常见的一种类型。大气中PM2.5可通过对骨代谢的影响，引发或加剧绝经后骨质疏松，但其具体影响机制尚未明确。文章就PM2.5与PMOP的相关性及作用机制进行综述。
Abstract:
-

参考文献/References:

[1]郭郡浩,姚茹冰,赵智明,等.利塞膦酸钠胶囊治疗绝经后骨质疏松症[J].医学研究生学报,2009,22(2):154-157.
[2]王柄棋,孙雨晴,陈翔,等.绝经后骨质疏松症药物治疗的现状与思考[J].中国骨质疏松杂志,2017,23(6):818-823.
[3]游利.骨质疏松症的现状、筛查和预防[J].中国全科医学,2016,19(14):1616-1619.
[4]朱文瑜.PM2.5事件与中国绿色公共领域的形成[J].科普研究,2015,10(3):40-49.
[5]郑小花,黄惠娟,王榕娟. PM2.5对骨质疏松症的影响研究[J]. 中国骨质疏松杂志,2016,22(1):111-114.
[6]Ogliari KS, Lichtenfels AJ, de Marchi MR, et al. Intrauterine exposure to diesel exhaust diminishes adult ovarian reserve[J]. Fertil Steril,2013,99(6):1681-1688.
[7]Li R, Navab K, Hough G, et al. Effect of exposure to atmospheric ultrafine particles on production of free fatty acids and lipid metabolites in the mouse small intestine[J]. Environ Health Perspect, 2015,123(1):34-41.
[8]Alvr K, Meyer HE, Falch JA, et al. Outdoor air pollution and bone mineral density in elderly men-the Oslo Health Study[J]. Osteoporos Int,2007,18(10):1669-1674.
[9]Brunekreef B, Beelen R, Hoek G, et al. Effects of long-term exposure to traffic-related air pollution on respiratory and cardiovascular mortality in the Netherlands: the NLCS-AIR study[J]. Res Rep Health Eff Inst, 2009,(139):5-71,73-89.
[10]赵妤希,陈义珍,杨欣,等.北京市中心城区PM2.5长期变化趋势和特征[J].生态环境学报,2016,25(9):1493-1498.
[11]王亮,马远征,张妍,等.北京地区9103例体检人群骨密度流行病学调查研究[J].中国骨质疏松杂志,2014,20(8):952-955.
[12]Calderon-Garciduenas L, Mora-Tiscareno A, Francolira M, et al. Exposure tourban air pollution and bone health in clinically healthy six-year-old children[J]. Arh Hig Rada Toksikol,2013,64(1):23-34.
[13]Liu C, Fuertes E, Flexeder Cm, et al. Associations between ambient air pollution and bone turnover markers in 10-year old children: results from the GINIplus and LISAplus studies[J]. Int J Hyg Environ Health,2015,218(1): 58-65.
[14]李雪雪,张红霞,郑昕蕊,等.PM2.5暴露对小鼠卵巢雌、孕激素受体表达的影响[J].现代妇产科进展,2017,26(5):369-372.
[15]Tian L, Zhang W, Lin ZQ, et al. Impact of traffic emissions on local air quality and the potential toxicity of traffic-related particu-lates in Beijing, China[J].Biomed Environ Sc,2012,25(6):663.
[16]赵璨,廖纪萍,王广发.免疫调节在颗粒物质诱导气道炎性反应中的作用[J].中国医学前沿杂志(电子版),2014,6(2):29-33.
[17]Cyphert JM, Nyska A, Mahoney RK, et al. Sumas Mountain chrysotile induces greater lung fibrosis in Fischer344 rats than Libby amphibole, El Dorado tremolite, and Ontario ferroactinolite[J]. Toxicol Sci, 2012, 130(2):405-415.
[18]郑小花,黄惠娟.左归丸联合橄榄油对大鼠去势后骨组织和骨密度的影响[J].东南国防医药,2014,16(1):10-13.
[19]赵熠,蔡育,王贻宁.破骨细胞前体细胞的研究进展[J].国际口腔医学杂志,2011,38(6):670-673.
[20]Islander U, Jochems C, Lagerquist MK, et al. Estrogens in rheumatoid arthritis; the immune system and bone[J]. Mol Cell Endocrinol,2011,335(1):14-29.
[21]邹世恩,张绍芬.细胞因子在绝经后骨质疏松症发病机制中的作用[J].中国骨质疏松杂志,2012,18(4):375-380.
[22]王娜,黄智胜,白艳甫.中药膏方联合火针治疗绝经后骨质疏松症的临床疗效及对血清白细胞介素-6、骨保护素水平的影响[J].河北中医,2016,38(6):817-821.
[23]Papanicolaou DA, Wilder RL, Manolagas SC, et al. The pathophysiologic roles of interleukin-6 in human disease[J]. Ann Intern Med,1998,128:127-137.
[24]Kim JY,Lee EY, Choi I, et al, Effects of the Particulate Matter2.5 (PM2.5) on Lipoprotein Metabolism, Uptake and Degradation, and Embryo Toxicity[J]. Mol Cells,2015,38(12):1096-1104.
[25]徐定波,涂萍,段鹏.绝经后女性骨密度与脂代谢相关性研究[J].中国骨质疏松杂志,2015,21(11):1347-1350.
[26]王景,李小梅,洪苑.脂代谢及血清脂联素水平与绝经后骨质疏松症的相关性研究[J].实用妇产科杂志,2014,30(11):828-830.
[27]Liu C, Bai Y, Xu X, et al. Exaggerated effects of particulate matter airpollution in genetic typeⅡdiabetes mellitus[J].Part Fibre Toxicol,2014,11(1):27.
[28]蔡晓燕,董光富.脂代谢及血清骨钙素水平与骨质疏松症的相关性分析[J].中国骨质疏松杂志,2016,22(6):711-712,730.
[29]王想福,孙凤歧,叶丙霖,等.破骨细胞与骨质疏松症的关系研究进展[J].中国骨质疏松杂志,2015,21(11):1420-1424.
[30]冯志尉,李伟. PPARγ与激素性股骨头坏死的研究进展[J].西部医学,2017,29(7):1032-1036.
[31]宋明宇,王蓉,杨勇,等.地塞米松对骨髓间充质细胞增殖及成骨、成脂分化的效应[J].骨科,2017,8(4):302-308.
[32]齐姗,徐胜前,肖会.过氧化物酶体增殖物激活受体γ在骨质疏松及类风湿关节炎中的研究进展[J].中国医药,2015,(8):1245-1248.
[33]徐帅,李世昌,方幸,赵常红.运动对T2DM中骨钙素介导的能量代谢调控机制[J].中国体育科技,2018,54(01):129-135.
[34]Reinehr T, Roth C. A new link between skeleton, obesity and insulin resistance: relationships between osteocalcin, leptin and insulin resistance in obese children before and after weight loss[J].Int J Obes (Lond),2010,34(5):852-858.
[35]李振.老年女性骨质疏松患者血清中白细胞介素-6、-8、骨钙素和雌二醇的表达及意义[J].中国老年学杂志,2016,36(13):3273-3275.
[36]于一云,付思思,刘磊,等.瘦素通过NLRP3炎性体对小鼠骨髓树突状细胞的作用及机制[J].中国免疫学杂志,2017,33(7):971-975.
[37]Kocyigit H, Bal S,Atay A, et al. Plasma leptin values in postmenopausal women with osteoporosis[J]. Bosn J Basic Med Sci,2013,13(3):192-196.
[38]刘冬梅,刘建民.骨钙素对糖代谢的调控作用[J].中华骨质疏松和骨矿盐疾病杂志,2015,2:97-102.
[39]王景,蒋欣峰,李小梅,等.绝经后老年骨质疏松患者血清脂联素与骨代谢生化指标的相关性[J].中国老年学杂志,2015,35(2):360-361.
[40]柯贤柱,葛鹏,石芳.绝经后骨质疏松患者血清脂联素与瘦素和炎性细胞因子的相关性研究[J].中华关节外科杂志(电子版),2012,6(3):47-49.
[41]Di Mascio L, Voermans C, Uqoezwa M, et al. Identification of adiponectin as a novel hemopoietic stem cell growth factor[J].J Immunol,2007,178(6):3511-3520．

相似文献/References:

[1]林妹珠,倪清丽综述,黄惠娟审校.PM2.5通过ER/RANK通路调节骨代谢的研究进展[J].医学研究与战创伤救治(原医学研究生学报),2020,22(2):178.[doi:10.3969/j.issn.1672-271X.2020.02.014]
　LIN Mei zhu,NI Qing li reviewing,HUANG Hui juan checking.Study on the regulation of bone metabolism by PM2.5 through ER/RANK pathway[J].JOURNAL OF MEDICALRESEARCH —COMBAT TRAUMA CARE,2020,22(05):178.[doi:10.3969/j.issn.1672-271X.2020.02.014]

备注/Memo

备注/Memo:
基金项目：国家自然科学基金(8177061355)
更新日期/Last Update: 2018-09-20